Genes
Page 10 of 264, showing 20 records out of 5271 total, starting on record 181, ending on 200
Public Gene Name | Sequence Name | WB ID | Description | Module | Actions |
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B0563.1 | B0563.1 | WBGene00015261 |
lemone_42_gene |
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B0563.7 | B0563.7 | WBGene00015264 |
lemone_96_gene |
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B0564.11 | B0564.11 | WBGene00023421 |
lemone_16_gene |
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B0564.4 | B0564.4 | WBGene00007204 |
lemone_2_gene |
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B0564.7 | B0564.7 | WBGene00007207 |
lemone_128_gene |
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bar-1 | C54D1.6 | WBGene00000238 |
bar-1 encodes a beta-catenin; during C. elegans development, BAR-1 likely functions as a transcriptional coactivator whose activity is required for Q neuroblast migration, P12 cell fate specification, and P3.p through P8.p vulval cell fate specification at two different stages of development; in specifying vulval cell fates, bar-1 interacts with Wnt and MAPK signaling pathways to regulate proper expression of the LIN-39 homeodomain transcription factor, overexpresion of which can partially rescue the bar-1 mutant phenotype; in yeast two-hybrid assays, BAR-1 interacts strongly with the POP-1/TCF transcription factor, and when fused to the Gal4 DNA binding domain, BAR-1 can function in yeast as a transcriptional coactivator; during larval development, BAR-1 expression begins in P3.p through P8.p at the late L1 stage and then disappears from these cells by the mid-L3 stage; BAR-1 is also expressed in P12, in the seam cells, and in cells of the somatic gonad; BAR-1 subcellular localization, assessed using an integrated transgene, reveals localization to the cytoplasm, nucleus, and cell junctions; genetic mosaic analyses indicate that, in P4.p and in P12, bar-1 acts cell autonomously to specify cell fates.
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lemone_299_regulator |
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bas-1 | C05D2.4 | WBGene00000239 |
bas-1 encodes a serotonin- and dopamine-synthetic aromatic amino acid decarboxylase (AAADC) that is required for the synthesis of serotonin from 5-hydroxytryptophan in vivo; mutations of bas-1 impair the turning step in male mating, the migration of AVM, SDQR, ALM, and BDU neurons during development.
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lemone_70_gene |
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bath-10 | Y49F6C.4 | WBGene00021726 |
lemone_251_gene |
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bath-15 | C08C3.2 | WBGene00015590 |
lemone_66_gene |
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bath-26 | T07H3.6 | WBGene00020329 |
lemone_125_gene |
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bath-31 | F12E12.4 | WBGene00017405 |
lemone_50_gene |
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bath-33 | C08E3.3 | WBGene00015595 |
lemone_146_gene |
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bath-38 | F52H3.3 | WBGene00009945 |
lemone_68_gene |
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bath-41 | F37A4.9 | WBGene00018137 |
The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
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lemone_21_gene |
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bath-5 | F59H6.11 | WBGene00019141 |
lemone_66_gene |
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bath-9 | Y49F6C.3 | WBGene00021725 |
lemone_153_gene |
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bbs-5 | R01H10.6 | WBGene00010974 |
lemone_108_gene |
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bbs-8 | T25F10.5 | WBGene00000244 |
bbs-8 encodes a tetratricopeptide repeat (TPR)-containing protein that is orthologous to the human Bardet-Biedl syndrome protein, BBS8; in C. elegans, bbs-8 activity is required for cilia biogenesis and function; accordingly, bbs-8 mutant animals display odorant chemotaxis defects and exhibit both aberrant motility and abnormal localization of at least two intraflagellar transport (IFT) protein markers; a BBS-8::GFP translational fusion is expressed exclusively in ciliated head and tail neurons, where it localizes predominantly to the base of cilia, known as the ciliary transition zone; BBS-8::GFP is also observed moving bidirectionally (anterograde and retrograde) along the ciliary axoneme; DNA sequences upstream of bbs-8 contain X box DNA binding sites, suggesting that bbs-8 expression may be regulated by the DAF-19 RFX-type transcription factor.
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lemone_17_gene |
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bbs-9 | C48B6.8 | WBGene00016744 |
lemone_173_gene |
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bcat-1 | K02A4.1 | WBGene00001149 |
bcat-1 encodes a branched-chain amino acid aminotransferase that, by homology, is predicted to catalyze the first reaction in the catabolism of essential branched-chain amino acids such as leucine, isoleucine, and valine; in C. elegans, large-scale RNA-mediated interference (RNAi) screens indicate that bcat-1 activity is required for embryonic and larval development.
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lemone_14_gene |
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