Module
- Number
- 251
- Regulatory Genes
- 6
- Module Genes
- 4
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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eya-1 | C49A1.4 | WBGene00001377 | 321 |
eya-1 encodes a protein orthologous to the Eyes absent/Eya Drosophila protein which is involved in eye development and has protein tyrosine phosphatase ; RNA interference and mutant studies indicate that eya-1 is involved in embryonic and larval tissue morphogenesis as well as larval viability; eya-1 mutants show increased embryonic cell deaths due to activation of the cell death pathway; eya-1 functions redundantly with vab-3/eyeless to control larval viability and anterior body morphogenesis; GFP studies show that eya-1 is expressed in a subset of nuclei during embryonic morphogenesis; the human genes EYA1 and EYA4, when mutated, lead to disease syndromes.
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lir-2 | F18A1.4 | WBGene00003045 | 202 |
lir-2 encodes a LIN-26-like zinc-finger protein that shares a unique C2H2 motif together with LIR-1, LIR-3, and LIN-26; lir-2 is the upstream gene in an operon with lir-1 which is, in turn, the upstream gene in a second, overlapping operon with lin-26; as loss of lir-2 function via RNAi results in no obvious abnormalities, the precise role of lir-2 in C. elegans development and/or behavior is not yet known; lir-2 transcripts are ubiquitous in early embryos (2-200-cell stages).
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hmg-11 | T05A7.4 | WBGene00001976 | 165 | View | |
K05F1.5 | K05F1.5 | WBGene00019407 | 149 | View | |
F42G2.6 | F42G2.6 | WBGene00018355 | 147 | View | |
F13C5.2 | F13C5.2 | WBGene00017423 | 120 | View |