Module
- Number
- 173
- Regulatory Genes
- 6
- Module Genes
- 15
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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unc-42 | F58E6.10 | WBGene00006778 | 398 |
unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
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aptf-1 | K06A1.1 | WBGene00019424 | 240 |
K06A1.1 encodes an AP-2-like transcription factor.
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nhr-167 | C49F5.4 | WBGene00008208 | 199 | View | |
hlh-15 | C43H6.8 | WBGene00001959 | 161 | View | |
Y34B4A.8 | Y34B4A.8 | WBGene00021324 | 155 | View | |
odr-3 | C34D1.3 | WBGene00003850 | 148 |
odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
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CLR Predictions
5 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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bbs-9 | C48B6.8 | WBGene00016744 | View | |
C25E10.11 | C25E10.11 | WBGene00016100 | View | |
F43C1.1 | F43C1.1 | WBGene00009647 | View | |
F45H7.6 | F45H7.6 | WBGene00009738 | View | |
F46B6.2 | F46B6.2 | WBGene00009768 | View | |
F55A4.3 | F55A4.3 | WBGene00018855 | View | |
F58B4.2 | F58B4.2 | WBGene00010235 | View | |
F59B2.9 | F59B2.9 | WBGene00010311 |
This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
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grl-11 | ZK512.9 | WBGene00001720 |
grl-11 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; GRL-11 is expressed in larval pharynx; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
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hlh-15 | C43H6.8 | WBGene00001959 | View | |
ift-74 | C18H9.8 | WBGene00016005 | View | |
ins-21 | M04D8.1 | WBGene00002104 |
ins-21 encodes an insulin-like peptide.
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oac-51 | W03B1.7 | WBGene00020976 | View | |
T15D6.12 | T15D6.12 | WBGene00011786 | View | |
ZK994.6 | ZK994.6 | WBGene00022842 | View |