Genes
Page 2 of 264, showing 20 records out of 5271 total, starting on record 21, ending on 40
| Public Gene Name | Sequence Name | WB ID | Description | Module | Actions |
|---|---|---|---|---|---|
| acdh-12 | E04F6.5 | WBGene00017125 |
E04F6.5 is orthologous to the human gene ACYL-CoA DEHYDROGENASE, VERY LONG-CHAIN (OMIM:201475), which when mutated leads to VLCAD deficiency, an inborn error of mitochondrial beta-oxidation.
|
lemone_43_gene |
View |
| acdh-2 | C17C3.12 | WBGene00015894 |
acdh-2 encodes a short-chain acyl-CoA dehydrogenase; ACDH-2 is predicted to be a mitochondrial enzyme that catalyzes the first step of fatty acid beta-oxidation and thus plays a key role in energy production; steady-state acdh-2 mRNA levels are under the control of the MDT-15 mediator complex subunit; in addition, gene expression studies indicate that acdh-2 expression is downregulated in fasted animals; loss of acdh-2 activity via large-scale RNAi experiments does not result in any obvious defects.
|
lemone_318_gene |
View |
| acdh-4 | T10E9.9 | WBGene00020419 |
lemone_53_gene |
View | |
| acdh-6 | C02D5.1 | WBGene00015335 |
lemone_102_gene |
View | |
| acdh-8 | K05F1.3 | WBGene00019406 |
lemone_147_gene |
View | |
| acdh-9 | F28A10.6 | WBGene00017874 |
lemone_244_gene |
View | |
| ace-3 | Y48B6A.8 | WBGene00000037 |
ace-3 encodes one of four C. elegans acetylcholinesterases (AChE); ACE-3 represents ~5% of the total AChE activity in C. elegans and in vitro, hydrolyzes acetylthio-, butyrylthio-, and propionylthiocholine substrates with equal efficiency; although loss-of-function mutations in ace-3 result in no obvious defects, animals doubly mutant with ace-1 or ace-2 have slight defects in backward locomotion and animals triply mutant for ace-1, -2, and -3 arrest as unhatched, yet fully developed, embryos; ace-3 is the downstream gene in an operon with a fourth AChE-encoding gene, ace-4, and transcriptional reporter fusions with ace-4 upstream sequences direct expression in pharyngeal muscles pm3, 4, 5, and 7, the two CAN (canal associated neuron) cells, midbody dorsal body wall muscles in larvae, and several neurons in the head and anal ganglion
|
lemone_65_gene |
View |
| acl-2 | T06E8.1 | WBGene00011543 |
T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
|
lemone_43_gene |
View |
| acl-7 | Y46G5A.21 | WBGene00012911 |
Y46G5A.21 is orthologous to the human gene GLYCERONEPHOSPHATE O-ACYLTRANSFERASE (GNPAT; OMIM:602744), which when mutated leads to disease.
|
lemone_119_gene |
View |
| acl-9 | ZK40.1 | WBGene00022646 |
lemone_26_gene |
View | |
| acn-1 | C42D8.5 | WBGene00000039 |
acn-1 encodes an ACE-like protein required for larval development and adult morphogenesis, and probably for cell fusion in larval seam cells; ACN-1 lacks not only the HExxH consensus metallopeptidase motif, but also other active site residues found in the sequence HEAI/VxD of mammalian and insect ACEs; acn-1 is expressed in hypodermal cells, vulval precursor cells, and ray papillae in the male tail; the hypodermal expression of acn-1 appears to be controlled by nhr-23 and nhr-25.
|
lemone_20_gene |
View |
| aco-1 | ZK455.1 | WBGene00000040 |
aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment.
|
lemone_101_gene |
View |
| aco-2 | F54H12.1 | WBGene00000041 |
aco-2 encodes an aconitase homolog that is required for embryonic viability, fertility, locomotion, and vulval morphogenesis, and perhaps for normal lifespan; ACO-2 is predicted to be mitochondrial.
|
lemone_113_gene |
View |
| acr-11 | D2092.3 | WBGene00000050 |
A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
|
lemone_17_gene |
View |
| acr-14 | T05C12.2 | WBGene00000053 |
acr-14 encodes a protein that contains neurotransmitter-gated ion-channel ligand-binding and transmembrane domains.
|
lemone_17_gene |
View |
| acr-15 | F25G6.4 | WBGene00000054 |
A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
|
lemone_96_gene |
View |
| acr-18 | F28F8.1 | WBGene00000057 |
acr-18 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-18 falls into the 'DEG-3' class of nAChR subunits, apparently unique to nematodes, which includes DEG-3, DES-2, ACR-5, ACR-17, ACR-20, and ACR-23.
|
lemone_181_gene |
View |
| acs-16 | F37C12.7 | WBGene00018152 |
lemone_47_gene |
View | |
| act-3 | T04C12.4 | WBGene00000065 |
act-3 encodes an invertebrate actin, highly similar to ACT-1, ACT-2, and ACT-4, that functions in body wall muscle; act-3 functions with two other action isoforms, act-1 and act-2, to control cytoplasmic microfilament function in the early embryo.
|
lemone_124_gene |
View |
| act-5 | T25C8.2 | WBGene00000067 |
an ortholog of human cytoplasmic actin; and is expressed only in microvillous intestinal cells and excretory cell.
|
lemone_130_gene |
View |
