Module
- Number
- 20
- Regulatory Genes
- 5
- Module Genes
- 34
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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rab-3 | C18A3.6 | WBGene00004267 | 867 |
rab-3 encodes a rab3 homolog, a member of the Ras GTPase superfamily, and affects sensitivity to aldicarb and the distribution of synaptic vesicle populations and thereby affects synaptic transmission, track amplitude and speed of movement, chemotaxis to isoamyl alcohol, affects pharyngeal pump durations, and may only slightly affect male mating behavior; requires aex-3 for localization to synapse-rich regions in axons and it is expressed in most or all neurons.
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C12D12.5 | C12D12.5 | WBGene00015716 | 392 | View | |
zbed-6 | F25H8.6 | WBGene00009133 | 235 |
zbed-6 encodes a protein that contains a BED-type zinc finger domain; loss of zbed-6 activity in large-scale RNAi screens indicates that zbed-6 is required for larval development.
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F17A9.3 | F17A9.3 | WBGene00017535 | 152 | View | |
nhr-230 | Y17D7A.1 | WBGene00012446 | 104 | View |
CLR Predictions
55 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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acn-1 | C42D8.5 | WBGene00000039 |
acn-1 encodes an ACE-like protein required for larval development and adult morphogenesis, and probably for cell fusion in larval seam cells; ACN-1 lacks not only the HExxH consensus metallopeptidase motif, but also other active site residues found in the sequence HEAI/VxD of mammalian and insect ACEs; acn-1 is expressed in hypodermal cells, vulval precursor cells, and ray papillae in the male tail; the hypodermal expression of acn-1 appears to be controlled by nhr-23 and nhr-25.
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BE10.2 | BE10.2 | WBGene00007210 | View | |
bus-8 | T23F2.1 | WBGene00044623 |
bus-8 is an uncloned gene required for colonization by Microbacterium nematophilum and the tail-swelling response to M. nematophilum infection; bus-8 is also required for cuticle integrity, normal cuticle antigens, completely normal traction during movement, and viability.
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C05E7.1 | C05E7.1 | WBGene00007343 | View | |
C05E7.2 | C05E7.2 | WBGene00007344 | View | |
C14A4.9 | C14A4.9 | WBGene00007560 | View | |
C15C6.1 | C15C6.1 | WBGene00007600 | View | |
clec-180 | F32E10.3 | WBGene00017991 | View | |
D2096.6 | D2096.6 | WBGene00017073 | View | |
elo-4 | C40H1.4 | WBGene00001242 |
The elo-4 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; its function in vivo is unknown.
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F11E6.8 | F11E6.8 | WBGene00008711 | View | |
F22F4.1 | F22F4.1 | WBGene00017716 | View | |
F30H5.3 | F30H5.3 | WBGene00017937 | View | |
F33D4.6 | F33D4.6 | WBGene00017998 | View | |
F35B3.4 | F35B3.4 | WBGene00018031 | View | |
F41E6.11 | F41E6.11 | WBGene00018292 | View | |
F56D3.1 | F56D3.1 | WBGene00018969 | View | |
F58E6.1 | F58E6.1 | WBGene00010251 |
The F58E6.1 encodes a protein that may be involved in apoptosis.
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F58H1.2 | F58H1.2 | WBGene00010285 | View | |
K04H4.2 | K04H4.2 | WBGene00010573 |
K04H4.2 encodes, by alternative splicing, three proteins ranging from 628 to 1446 residues in length; K04H4.2 proteins are predicted to be secreted, with an N-terminal chitin-binding peritrophin-A domain followed by up to 15 cysteine-rich domains; the general organization of K04H4.2 protein resembles that of T10E10.4; in mass RNAi assays, K04H4.2 is required for larval growth and locomotion; K04H4.2 transcription is upregulated by hypoxia, in parallel with ketn-1.
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K08B12.1 | K08B12.1 | WBGene00019520 | View | |
K10D3.4 | K10D3.4 | WBGene00010738 | View | |
lgc-27 | Y74E4A.1 | WBGene00022283 | View | |
M03F4.6 | M03F4.6 | WBGene00019759 | View | |
phg-1 | F27E5.4 | WBGene00004017 | View | |
pqn-13 | C14C11.8 | WBGene00004104 |
The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
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ptr-1 | C24B5.3 | WBGene00004216 |
ptr-1 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; individually, PTR-1 is weakly required for normal molting from L4 to adult stages; however, PTR-1, in conjunction with either PTR-16 alone or with PTR-6 and PTR-10, is strongly required for both molting and viability, with double ptr-1/-16 or triple ptr-1/-6/-10 RNAi animals showing pronounced molting defects and lethality; PTR-1 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development.
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T03G6.1 | T03G6.1 | WBGene00020194 | View | |
T19A5.3 | T19A5.3 | WBGene00020554 | View | |
W04G3.1 | W04G3.1 | WBGene00012255 | View | |
Y64H9A.2 | Y64H9A.2 | WBGene00022024 | View | |
Y75B7AR.1 | Y75B7AR.1 | WBGene00022287 | View | |
ZC123.1 | ZC123.1 | WBGene00022517 | View | |
ZK682.5 | ZK682.5 | WBGene00022789 | View |