Gene: Sopen11g003420
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen11g003420
- Transcript Identifier Sopen11g003420.1
- Gene Type Coding gene
- Location Spenn-ch11 : 1918190-1927222 : negative
Gene Family Information
- ID HOM05D001201
- #Genes/#Species 520/96
- Phylogenetic origin
- ID ORTHO05D001100
- #Genes/#Species 487/96
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid Sopen11g003420.1
Descriptions
- Description Encodes a DNA glycosylase DEMETER (DME). Responsible for endosperm maternal-allele-specific hypomethylation at the MEDEA (MEA) gene. DME can excise 5-methylcytosine in vitro and when expressed in E. coli. DME establishes MEA imprinting by removing 5-methylcytosine to activate the maternal allele. | DEMETER (DME) | CONTAINS InterPro DOMAIN/s: DNA glycosylase , Endonuclease III-like, iron-sulphur cluster loop motif , HhH-GPD domain | BEST Arabidopsis thaliana protein match is: demeter-like 1
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) | 
|---|---|---|---|---|
| GO:0006349 | ISO | PLAZA Integrative Orthology | regulation of gene expression by genetic imprinting | AT5G04560 | 
| GO:0010216 | ISO | PLAZA Integrative Orthology | maintenance of DNA methylation | AT4G34060 | 
| GO:0010150 | ISO | PLAZA Integrative Orthology | leaf senescence | AT4G34060 | 
| GO:0009793 | ISO | PLAZA Integrative Orthology | embryo development ending in seed dormancy | AT5G04560 | 
| GO:0006306 | ISO | PLAZA Integrative Orthology | DNA methylation | AT5G04560 | 
| GO:0009836 | ISO | PLAZA Integrative Orthology | fruit ripening, climacteric | Solyc11g007580.3 | 
| GO:0010154 | ISO | PLAZA Integrative Orthology | fruit development | Solyc11g007580.3 | 
| GO:0006281 | IEA | InterPro | DNA repair | |
| GO:0006284 | IEA | InterPro | base-excision repair | |
| GO:0080111 | IEA | InterPro | DNA demethylation | 
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) | 
|---|---|---|---|---|
| GO:0051747 | ISO | PLAZA Integrative Orthology | cytosine C-5 DNA demethylase activity | AT4G34060 | 
| GO:0003906 | ISO | PLAZA Integrative Orthology | DNA-(apurinic or apyrimidinic site) endonuclease activity | AT5G04560 | 
| GO:0019104 | IEA | InterPro | DNA N-glycosylase activity | |
| GO:0051539 | IEA | InterPro | 4 iron, 4 sulfur cluster binding | |
| GO:0003824 | IEA | InterPro | catalytic activity | |
| GO:0035514 | IEA | InterPro | DNA demethylase activity | 
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) | 
|---|---|---|---|---|
| GO:0043078 | ISO | PLAZA Integrative Orthology | polar nucleus | AT5G04560 | 
| GO:0005634 | ISO | PLAZA Integrative Orthology | nucleus | AT4G34060 | 
Color Legend
| Experimental Evidence | 
| Computational Reviewed Evidence | 
| Electronic Evidence | 
| InterPro | Description | 
|---|---|
| IPR023170 | Helix-hairpin-helix, base-excision DNA repair, C-terminal | 
| IPR044811 | DNA glycosylase, plant | 
| IPR028925 | Demeter, RRM-fold domain | 
| IPR003265 | HhH-GPD domain | 
| IPR011257 | DNA glycosylase | 
| IPR003651 | Endonuclease III-like, iron-sulphur cluster loop motif | 
| IPR028924 | Permuted single zf-CXXC unit | 
| Mapman id | Description | 
|---|---|
| 12.5.3.1 | Chromatin organisation.DNA methylation.ROS1-mediated DNA demethylation.methylcytosine-specific DNA glycosylase (ROS1) |