Gene: AT5G04560
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT5G04560
- Transcript Identifier AT5G04560.3
- Gene Type Coding gene
- Location Chr5 : 1310671-1318091 : positive
Gene Family Information
- ID HOM05D001201
- #Genes/#Species 520/96
- Phylogenetic origin
- ID ORTHO05D001100
- #Genes/#Species 487/96
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT5G04560.3
- symbol DME
- full_name DEMETER
- uniprot Q8LK56
Descriptions
- Description HhH-GPD base excision DNA repair family protein
- Computational description DEMETER (DME); CONTAINS InterPro DOMAIN/s: DNA glycosylase (InterPro:IPR011257), Endonuclease III-like, iron-sulphur cluster loop motif (InterPro:IPR003651), HhH-GPD domain (InterPro:IPR003265); BEST Arabidopsis thaliana protein match is: demeter-like 1 (TAIR:AT2G36490.1); Has 3638 Blast hits to 3482 proteins in 1335 species: Archae - 238; Bacteria - 2315; Metazoa - 178; Fungi - 96; Plants - 343; Viruses - 0; Other Eukaryotes - 468 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0048229 | ISO | PLAZA Integrative Orthology | gametophyte development | Os01g0218032 |
| GO:0009836 | ISO | PLAZA Integrative Orthology | fruit ripening, climacteric | Solyc11g007580.3 |
| GO:0010154 | ISO | PLAZA Integrative Orthology | fruit development | Solyc11g007580.3 |
| GO:0006281 | IEA | GOA Database | DNA repair | |
| GO:0006281 | IEA | InterPro | DNA repair | |
| GO:0080111 | IEA | Gene Ontology | DNA demethylation | |
| GO:0080111 | IEA | InterPro | DNA demethylation | |
| GO:0006284 | IEA | Gene Ontology | base-excision repair | |
| GO:0006284 | IEA | InterPro | base-excision repair | |
| GO:0006306 | IDA | Gene Ontology | DNA methylation | 1 |
| GO:0006349 | IMP | Gene Ontology | regulation of gene expression by genetic imprinting | 2 |
| GO:0009793 | IMP | Gene Ontology | embryo development ending in seed dormancy | 3 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0051539 | IEA | GOA Database | 4 iron, 4 sulfur cluster binding | |
| GO:0051539 | IEA | InterPro | 4 iron, 4 sulfur cluster binding | |
| GO:0003824 | IEA | GOA Database | catalytic activity | |
| GO:0003824 | IEA | InterPro | catalytic activity | |
| GO:0035514 | IEA | Gene Ontology | DNA demethylase activity | |
| GO:0035514 | IEA | InterPro | DNA demethylase activity | |
| GO:0019104 | IEA | GOA Database | DNA N-glycosylase activity | |
| GO:0019104 | IDA ISS | Gene Ontology | DNA N-glycosylase activity | 1 3 |
| GO:0019104 | IEA | InterPro | DNA N-glycosylase activity | |
| GO:0016787 | IEA | GOA Database | hydrolase activity | |
| GO:0003677 | IEA | GOA Database | DNA binding | |
| GO:0051536 | IEA | GOA Database | iron-sulfur cluster binding | |
| GO:0003906 | IDA | Gene Ontology | DNA-(apurinic or apyrimidinic site) endonuclease activity | 1 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005634 | IEA | GOA Database | nucleus | |
| GO:0005634 | ISS, ISM | Gene Ontology | nucleus | 3 |
| GO:0043078 | IDA | Gene Ontology | polar nucleus | 3 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR003265 | HhH-GPD domain |
| IPR044811 | DNA glycosylase, plant |
| IPR028924 | Permuted single zf-CXXC unit |
| IPR011257 | DNA glycosylase |
| IPR023170 | Helix-hairpin-helix, base-excision DNA repair, C-terminal |
| IPR028925 | Demeter, RRM-fold domain |
| IPR003651 | Endonuclease III-like, iron-sulphur cluster loop motif |