InterPro domain: IPR023170

General Information

  • Identifier IPR023170
  • Description Helix-hairpin-helix, base-excision DNA repair, C-terminal
  • Number of genes 863
  • Gene duplication stats Loading...

Abstract

This entry represents the extreme C terminus of the helix-hairpin-helix base-excision DNA repair enzyme family, including the DNA glycosylases and lyases [ 1 , 2 , 3 ].


1. Structures of end products resulting from lesion processing by a DNA glycosylase/lyase. Chem. Biol. 11, 1643-9
2. Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure. EMBO J. 14, 4108-20
3. Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. Science 362, 834-839

Species distribution

Gene table