InterPro domain: IPR011257

General Information

  • Identifier IPR011257
  • Description DNA glycosylase
  • Number of genes 2110
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006281   GO:0003824  

Abstract

DNA glycosylases act to repair oxidative damage in DNA. These proteins are redundant as there are several different types of DNA glycosylases that are able to compensate for one another. Examples include the endonuclease III subfamily, the mismatch glycosylases subfamily, the 3-methyladenine DNA glycosylases I subfamily, and the DNA repair glycosylases subfamily [ 1 ].


1. DNA N-glycosylase deficient mice: a tale of redundancy. Mutat. Res. 531, 165-75

Species distribution

Gene table