Child MapMan terms
- Original MapMan term
- 19
- Description
- Protein homeostasis
- Type
- mapman
MapMan | description | genes | species | aco | aof | ash | ath | atr | bdi | calsi | cam | cre | egu | hvu | lpe | mac | mco | mpo | msi | obr | osa | osaindica | oth | pab | ped | peq | ppa | ptr | sbi | sit | sly | smo | spo | ssp | tae | ttu | vvi | zjn | zma | zma-b104 | zma-ph207 | zosmarina |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
19.2 | Protein homeostasis.ubiquitin-proteasome system | 21869 | 37 | 460 | 432 | 382 | 599 | 334 | 558 | 809 | 459 | 156 | 627 | 563 | 595 | 824 | 123 | 253 | 0 | 474 | 569 | 506 | 428 | 600 | 672 | 439 | 509 | 767 | 553 | 565 | 593 | 563 | 364 | 1378 | 1934 | 1129 | 430 | 480 | 690 | 0 | 656 | 396 |
19.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation | 14838 | 37 | 311 | 273 | 263 | 433 | 215 | 384 | 555 | 295 | 71 | 422 | 392 | 411 | 604 | 50 | 152 | 0 | 315 | 395 | 341 | 275 | 433 | 450 | 306 | 296 | 524 | 389 | 392 | 440 | 350 | 234 | 899 | 1390 | 781 | 287 | 333 | 482 | 0 | 436 | 259 |
19.4 | Protein homeostasis.proteolysis | 13729 | 37 | 315 | 242 | 201 | 348 | 293 | 366 | 439 | 342 | 91 | 237 | 405 | 381 | 348 | 80 | 158 | 0 | 309 | 377 | 345 | 250 | 474 | 356 | 262 | 266 | 456 | 360 | 386 | 372 | 364 | 223 | 1001 | 1359 | 765 | 318 | 211 | 404 | 0 | 403 | 222 |
19.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation) | 8556 | 37 | 168 | 147 | 152 | 258 | 116 | 227 | 281 | 163 | 30 | 237 | 240 | 246 | 356 | 23 | 81 | 0 | 168 | 230 | 202 | 156 | 265 | 263 | 166 | 157 | 290 | 241 | 243 | 229 | 206 | 126 | 515 | 824 | 464 | 161 | 207 | 303 | 0 | 267 | 148 |
19.2.2.1.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities | 7114 | 37 | 142 | 118 | 127 | 217 | 98 | 190 | 240 | 138 | 17 | 198 | 193 | 200 | 305 | 11 | 63 | 0 | 140 | 201 | 172 | 130 | 204 | 211 | 136 | 116 | 244 | 203 | 203 | 195 | 162 | 103 | 427 | 696 | 390 | 133 | 183 | 257 | 0 | 224 | 127 |
19.4.2 | Protein homeostasis.proteolysis.serine-type peptidase activities | 5920 | 37 | 114 | 122 | 92 | 178 | 116 | 169 | 207 | 142 | 50 | 121 | 171 | 157 | 146 | 39 | 64 | 0 | 131 | 146 | 140 | 101 | 197 | 153 | 127 | 129 | 207 | 153 | 156 | 168 | 155 | 101 | 443 | 495 | 299 | 171 | 118 | 177 | 0 | 176 | 89 |
19.2.2.1.5.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities | 5179 | 37 | 104 | 86 | 94 | 152 | 66 | 139 | 193 | 92 | 7 | 146 | 143 | 143 | 245 | 5 | 36 | 0 | 100 | 146 | 122 | 91 | 143 | 149 | 98 | 77 | 180 | 148 | 147 | 143 | 112 | 75 | 279 | 507 | 282 | 95 | 153 | 206 | 0 | 173 | 102 |
19.1 | Protein homeostasis.protein quality control | 4848 | 37 | 108 | 110 | 95 | 116 | 81 | 112 | 187 | 111 | 36 | 146 | 127 | 122 | 172 | 36 | 57 | 0 | 106 | 119 | 109 | 86 | 111 | 158 | 92 | 131 | 162 | 118 | 123 | 113 | 149 | 103 | 351 | 378 | 213 | 88 | 106 | 170 | 0 | 165 | 81 |
19.2.2.8 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes | 4300 | 37 | 94 | 78 | 73 | 125 | 70 | 106 | 204 | 80 | 11 | 135 | 104 | 115 | 172 | 12 | 46 | 0 | 98 | 113 | 95 | 79 | 127 | 131 | 93 | 89 | 173 | 95 | 101 | 154 | 92 | 75 | 258 | 389 | 223 | 85 | 80 | 129 | 0 | 122 | 74 |
19.4.3 | Protein homeostasis.proteolysis.aspartic-type peptidase activities | 3535 | 37 | 109 | 41 | 41 | 70 | 73 | 90 | 101 | 105 | 3 | 15 | 128 | 90 | 80 | 2 | 44 | 0 | 87 | 130 | 100 | 70 | 175 | 87 | 52 | 40 | 93 | 102 | 117 | 97 | 72 | 52 | 262 | 439 | 250 | 52 | 5 | 110 | 0 | 105 | 46 |
19.4.3.1 | Protein homeostasis.proteolysis.aspartic-type peptidase activities.A1-class protease (Pepsin) | 3535 | 37 | 109 | 41 | 41 | 70 | 73 | 90 | 101 | 105 | 3 | 15 | 128 | 90 | 80 | 2 | 44 | 0 | 87 | 130 | 100 | 70 | 175 | 87 | 52 | 40 | 93 | 102 | 117 | 97 | 72 | 52 | 262 | 439 | 250 | 52 | 5 | 110 | 0 | 105 | 46 |
19.2.2.8.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes | 3411 | 37 | 72 | 63 | 59 | 103 | 50 | 79 | 178 | 70 | 6 | 103 | 84 | 85 | 137 | 8 | 36 | 0 | 82 | 95 | 76 | 64 | 105 | 107 | 74 | 60 | 144 | 77 | 83 | 126 | 70 | 62 | 198 | 297 | 162 | 68 | 71 | 102 | 0 | 97 | 58 |
19.2.2.1.5.3.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities.RING-H2-class E3 ligase | 2676 | 37 | 46 | 27 | 47 | 87 | 32 | 73 | 87 | 37 | 1 | 79 | 78 | 76 | 134 | 1 | 18 | 0 | 45 | 85 | 63 | 36 | 90 | 64 | 53 | 32 | 88 | 85 | 84 | 73 | 56 | 35 | 111 | 303 | 148 | 41 | 93 | 119 | 0 | 89 | 60 |
19.4.5 | Protein homeostasis.proteolysis.metallopeptidase activities | 2601 | 37 | 54 | 47 | 43 | 58 | 49 | 68 | 72 | 55 | 31 | 57 | 63 | 79 | 63 | 31 | 34 | 0 | 59 | 61 | 64 | 52 | 72 | 71 | 47 | 71 | 89 | 58 | 64 | 57 | 102 | 43 | 181 | 252 | 134 | 56 | 59 | 72 | 0 | 75 | 58 |
19.2.2.8.1.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components | 2520 | 37 | 51 | 46 | 47 | 76 | 44 | 60 | 116 | 49 | 2 | 81 | 49 | 58 | 109 | 4 | 31 | 0 | 55 | 63 | 51 | 54 | 70 | 89 | 63 | 41 | 121 | 60 | 61 | 98 | 59 | 53 | 151 | 181 | 108 | 55 | 60 | 82 | 0 | 73 | 49 |
19.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation | 2477 | 37 | 59 | 58 | 44 | 57 | 43 | 69 | 78 | 57 | 26 | 75 | 63 | 61 | 80 | 22 | 33 | 0 | 61 | 65 | 60 | 51 | 61 | 82 | 48 | 64 | 90 | 62 | 63 | 60 | 72 | 50 | 156 | 193 | 122 | 58 | 40 | 69 | 0 | 75 | 50 |
19.2.6 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome | 2460 | 37 | 47 | 50 | 39 | 57 | 43 | 59 | 99 | 61 | 35 | 69 | 61 | 61 | 72 | 34 | 36 | 0 | 53 | 59 | 58 | 54 | 50 | 79 | 51 | 78 | 82 | 54 | 60 | 48 | 77 | 41 | 192 | 178 | 108 | 43 | 66 | 77 | 0 | 79 | 50 |
19.4.2.2 | Protein homeostasis.proteolysis.serine-type peptidase activities.S10-class serine carboxypeptidase (SCPL) | 2153 | 37 | 34 | 45 | 24 | 54 | 44 | 72 | 81 | 62 | 8 | 49 | 68 | 66 | 44 | 3 | 11 | 0 | 53 | 56 | 53 | 37 | 92 | 56 | 56 | 20 | 62 | 58 | 57 | 60 | 30 | 25 | 169 | 211 | 129 | 58 | 57 | 57 | 0 | 66 | 26 |
19.2.2.8.1.4.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component FBX | 1942 | 37 | 41 | 33 | 36 | 62 | 32 | 46 | 81 | 38 | 2 | 63 | 36 | 41 | 87 | 4 | 24 | 0 | 43 | 49 | 40 | 39 | 55 | 69 | 49 | 34 | 103 | 45 | 46 | 82 | 46 | 39 | 113 | 139 | 84 | 45 | 42 | 61 | 0 | 54 | 39 |
19.3 | Protein homeostasis.autophagy | 1832 | 37 | 44 | 49 | 30 | 50 | 35 | 44 | 74 | 43 | 15 | 46 | 37 | 43 | 60 | 14 | 30 | 0 | 41 | 43 | 36 | 37 | 48 | 52 | 36 | 48 | 73 | 41 | 41 | 55 | 63 | 32 | 132 | 120 | 72 | 39 | 41 | 68 | 0 | 69 | 31 |
19.2.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation | 1678 | 37 | 42 | 40 | 29 | 37 | 29 | 47 | 54 | 40 | 15 | 50 | 35 | 40 | 56 | 11 | 21 | 0 | 42 | 47 | 41 | 37 | 42 | 60 | 32 | 38 | 60 | 40 | 44 | 39 | 46 | 34 | 113 | 131 | 84 | 41 | 27 | 47 | 0 | 55 | 32 |
19.4.1 | Protein homeostasis.proteolysis.cysteine-type peptidase activities | 1546 | 37 | 36 | 30 | 23 | 38 | 34 | 37 | 53 | 38 | 6 | 42 | 41 | 51 | 56 | 6 | 15 | 0 | 30 | 37 | 38 | 24 | 28 | 40 | 34 | 24 | 62 | 45 | 46 | 47 | 31 | 24 | 109 | 165 | 78 | 37 | 25 | 43 | 0 | 45 | 28 |
19.2.2.1.5.3.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities.RING-HC-class E3 ligase | 1471 | 37 | 33 | 29 | 28 | 32 | 20 | 37 | 69 | 34 | 4 | 43 | 35 | 37 | 61 | 3 | 12 | 0 | 32 | 35 | 34 | 30 | 30 | 50 | 29 | 31 | 57 | 40 | 39 | 39 | 38 | 24 | 93 | 115 | 77 | 29 | 37 | 56 | 0 | 55 | 24 |
19.2.6.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle | 1445 | 37 | 27 | 29 | 20 | 32 | 25 | 37 | 57 | 37 | 19 | 40 | 36 | 37 | 43 | 19 | 20 | 0 | 30 | 35 | 35 | 35 | 28 | 45 | 31 | 43 | 52 | 30 | 37 | 28 | 46 | 24 | 114 | 113 | 65 | 26 | 37 | 43 | 0 | 44 | 26 |
19.2.4 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD) | 1260 | 37 | 22 | 33 | 23 | 30 | 22 | 27 | 47 | 27 | 16 | 33 | 31 | 36 | 40 | 14 | 20 | 0 | 26 | 26 | 26 | 27 | 29 | 35 | 20 | 37 | 47 | 29 | 29 | 29 | 40 | 25 | 86 | 106 | 66 | 25 | 24 | 42 | 0 | 44 | 21 |
19.1.5 | Protein homeostasis.protein quality control.cytosolic Hsp70 chaperone system | 1237 | 37 | 27 | 28 | 24 | 32 | 15 | 32 | 41 | 30 | 4 | 31 | 31 | 33 | 48 | 5 | 9 | 0 | 31 | 32 | 34 | 26 | 28 | 46 | 21 | 31 | 45 | 31 | 33 | 31 | 31 | 24 | 93 | 95 | 54 | 14 | 26 | 50 | 0 | 45 | 26 |
19.2.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways | 1120 | 37 | 27 | 25 | 18 | 30 | 17 | 24 | 39 | 26 | 13 | 38 | 24 | 33 | 39 | 7 | 17 | 0 | 26 | 30 | 26 | 26 | 31 | 34 | 18 | 43 | 33 | 26 | 28 | 24 | 33 | 19 | 66 | 85 | 64 | 23 | 23 | 31 | 0 | 32 | 22 |
19.2.3.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities | 1103 | 37 | 27 | 27 | 18 | 25 | 17 | 32 | 37 | 27 | 6 | 34 | 21 | 25 | 37 | 4 | 13 | 0 | 29 | 32 | 28 | 24 | 33 | 42 | 20 | 22 | 37 | 26 | 30 | 26 | 33 | 22 | 74 | 87 | 56 | 28 | 15 | 32 | 0 | 37 | 20 |
19.4.5.6 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities | 981 | 37 | 20 | 20 | 17 | 21 | 18 | 23 | 30 | 23 | 10 | 23 | 24 | 30 | 25 | 14 | 10 | 0 | 24 | 24 | 26 | 17 | 25 | 27 | 18 | 22 | 26 | 25 | 29 | 19 | 39 | 15 | 82 | 88 | 50 | 20 | 24 | 26 | 0 | 31 | 16 |
19.2.6.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle | 960 | 37 | 18 | 20 | 18 | 23 | 17 | 21 | 40 | 23 | 15 | 28 | 23 | 23 | 28 | 14 | 15 | 0 | 22 | 23 | 22 | 18 | 21 | 32 | 19 | 34 | 29 | 23 | 22 | 19 | 29 | 16 | 72 | 60 | 40 | 16 | 27 | 33 | 0 | 34 | 23 |
19.4.2.1 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families | 941 | 37 | 22 | 10 | 20 | 52 | 25 | 28 | 36 | 15 | 2 | 4 | 27 | 20 | 32 | 1 | 9 | 0 | 14 | 25 | 23 | 5 | 18 | 13 | 15 | 15 | 55 | 27 | 33 | 45 | 22 | 26 | 70 | 75 | 40 | 50 | 3 | 29 | 0 | 21 | 14 |
19.1.1 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery | 922 | 37 | 21 | 22 | 20 | 19 | 18 | 20 | 37 | 21 | 10 | 31 | 21 | 20 | 30 | 11 | 15 | 0 | 20 | 22 | 20 | 18 | 18 | 32 | 20 | 25 | 29 | 23 | 23 | 19 | 37 | 18 | 69 | 60 | 36 | 19 | 19 | 29 | 0 | 30 | 20 |
19.2.6.2.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components | 900 | 37 | 14 | 17 | 14 | 19 | 15 | 21 | 41 | 22 | 12 | 25 | 23 | 23 | 25 | 12 | 13 | 0 | 19 | 22 | 22 | 24 | 22 | 26 | 22 | 26 | 34 | 17 | 22 | 17 | 26 | 14 | 67 | 69 | 39 | 15 | 23 | 33 | 0 | 33 | 12 |
19.2.2.1.5.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RBR-type E3 ligase activities | 815 | 37 | 12 | 13 | 9 | 38 | 12 | 22 | 11 | 22 | 6 | 12 | 22 | 32 | 16 | 2 | 9 | 0 | 18 | 26 | 24 | 18 | 16 | 19 | 8 | 11 | 20 | 27 | 26 | 18 | 15 | 7 | 74 | 116 | 63 | 11 | 11 | 19 | 0 | 22 | 8 |
19.4.2.6 | Protein homeostasis.proteolysis.serine-type peptidase activities.S54-class protease (RBL)) | 778 | 37 | 17 | 18 | 14 | 20 | 13 | 22 | 19 | 20 | 8 | 23 | 19 | 24 | 21 | 9 | 11 | 0 | 19 | 19 | 19 | 18 | 18 | 24 | 15 | 21 | 21 | 21 | 20 | 18 | 21 | 12 | 57 | 59 | 39 | 15 | 17 | 24 | 0 | 28 | 15 |
19.2.2.1.5.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.U-Box E3 ligase activities | 759 | 37 | 17 | 9 | 17 | 20 | 14 | 19 | 26 | 14 | 1 | 27 | 20 | 17 | 34 | 1 | 12 | 0 | 14 | 21 | 20 | 15 | 33 | 28 | 23 | 15 | 31 | 19 | 19 | 20 | 25 | 13 | 52 | 50 | 29 | 19 | 15 | 21 | 0 | 17 | 12 |
19.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation) | 707 | 37 | 16 | 18 | 13 | 18 | 8 | 21 | 23 | 26 | 15 | 14 | 15 | 25 | 19 | 7 | 9 | 0 | 17 | 18 | 13 | 14 | 14 | 17 | 18 | 21 | 19 | 20 | 18 | 21 | 15 | 11 | 42 | 72 | 36 | 15 | 15 | 19 | 0 | 14 | 11 |
19.2.2.1.5.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.U-Box E3 ligase activities.E3 ubiquitin ligase (PUB) | 676 | 35 | 16 | 7 | 16 | 19 | 12 | 17 | 23 | 12 | 0 | 25 | 17 | 15 | 32 | 0 | 10 | 0 | 12 | 19 | 18 | 12 | 28 | 27 | 20 | 13 | 30 | 17 | 17 | 19 | 23 | 12 | 46 | 44 | 25 | 15 | 14 | 19 | 0 | 15 | 10 |
19.1.8 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities | 662 | 35 | 14 | 11 | 13 | 19 | 15 | 15 | 37 | 10 | 0 | 29 | 16 | 21 | 25 | 0 | 10 | 0 | 10 | 15 | 10 | 13 | 16 | 14 | 12 | 4 | 28 | 16 | 16 | 17 | 11 | 18 | 38 | 80 | 30 | 15 | 20 | 22 | 0 | 21 | 1 |
19.4.2.9 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex | 652 | 37 | 16 | 16 | 12 | 15 | 11 | 17 | 21 | 16 | 7 | 15 | 25 | 16 | 19 | 7 | 12 | 0 | 14 | 18 | 15 | 12 | 12 | 16 | 14 | 29 | 21 | 14 | 16 | 15 | 23 | 13 | 45 | 48 | 31 | 13 | 11 | 16 | 0 | 17 | 14 |
19.2.2.8.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.target protein binding component SKP1/ASK1 | 630 | 37 | 14 | 12 | 7 | 21 | 2 | 13 | 49 | 15 | 1 | 14 | 29 | 21 | 18 | 1 | 2 | 0 | 22 | 26 | 18 | 3 | 30 | 9 | 8 | 11 | 14 | 11 | 16 | 18 | 5 | 4 | 30 | 93 | 42 | 8 | 7 | 14 | 0 | 19 | 3 |
19.2.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation) | 623 | 37 | 10 | 11 | 11 | 14 | 9 | 17 | 20 | 16 | 10 | 15 | 19 | 15 | 16 | 7 | 8 | 0 | 16 | 19 | 17 | 13 | 13 | 17 | 10 | 19 | 19 | 19 | 17 | 16 | 21 | 10 | 46 | 58 | 31 | 12 | 9 | 16 | 0 | 16 | 11 |
19.1.7 | Protein homeostasis.protein quality control.Hsp60 chaperone system | 612 | 37 | 13 | 14 | 13 | 14 | 10 | 14 | 13 | 17 | 8 | 13 | 17 | 14 | 19 | 5 | 6 | 0 | 14 | 15 | 13 | 11 | 13 | 21 | 10 | 21 | 18 | 16 | 15 | 14 | 28 | 15 | 50 | 45 | 28 | 13 | 9 | 21 | 0 | 20 | 12 |
19.4.1.1 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C1-class protease (Papain) | 584 | 36 | 16 | 10 | 6 | 15 | 12 | 17 | 18 | 16 | 0 | 14 | 21 | 23 | 17 | 1 | 4 | 0 | 10 | 12 | 14 | 4 | 8 | 9 | 11 | 6 | 32 | 21 | 19 | 15 | 9 | 7 | 39 | 84 | 33 | 14 | 6 | 14 | 0 | 19 | 8 |
19.2.1.2 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway | 579 | 37 | 15 | 13 | 9 | 11 | 8 | 13 | 23 | 16 | 5 | 21 | 10 | 14 | 23 | 4 | 6 | 0 | 17 | 19 | 16 | 17 | 16 | 16 | 9 | 21 | 17 | 17 | 18 | 12 | 14 | 9 | 40 | 36 | 27 | 12 | 13 | 15 | 0 | 15 | 12 |
19.2.3.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities | 575 | 37 | 15 | 13 | 11 | 12 | 12 | 15 | 17 | 13 | 9 | 16 | 14 | 15 | 19 | 7 | 8 | 0 | 13 | 15 | 13 | 13 | 9 | 18 | 12 | 16 | 23 | 14 | 14 | 13 | 13 | 12 | 39 | 44 | 28 | 13 | 12 | 15 | 0 | 18 | 12 |
19.2.2.8.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes | 563 | 36 | 14 | 9 | 9 | 13 | 14 | 18 | 20 | 8 | 1 | 20 | 15 | 22 | 23 | 0 | 4 | 0 | 10 | 12 | 12 | 10 | 15 | 16 | 10 | 8 | 16 | 11 | 11 | 17 | 10 | 6 | 42 | 71 | 45 | 9 | 7 | 14 | 0 | 14 | 7 |
19.1.6 | Protein homeostasis.protein quality control.Hsp90 chaperone system | 557 | 37 | 14 | 12 | 9 | 11 | 7 | 12 | 37 | 14 | 5 | 15 | 9 | 13 | 20 | 6 | 7 | 0 | 12 | 14 | 13 | 11 | 16 | 16 | 11 | 19 | 19 | 12 | 15 | 13 | 15 | 12 | 43 | 30 | 18 | 13 | 18 | 18 | 0 | 19 | 9 |
19.1.5.2 | Protein homeostasis.protein quality control.cytosolic Hsp70 chaperone system.co-chaperone (Hsp40) | 552 | 37 | 10 | 12 | 9 | 15 | 8 | 15 | 15 | 13 | 2 | 13 | 14 | 14 | 20 | 3 | 3 | 0 | 14 | 15 | 16 | 15 | 17 | 20 | 10 | 17 | 19 | 14 | 16 | 13 | 14 | 10 | 43 | 36 | 20 | 7 | 14 | 24 | 0 | 26 | 6 |
19.2.2.1.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).polyubiquitination | 537 | 37 | 14 | 12 | 9 | 13 | 9 | 11 | 29 | 11 | 3 | 19 | 12 | 14 | 22 | 2 | 4 | 0 | 13 | 13 | 13 | 10 | 21 | 17 | 11 | 11 | 19 | 14 | 13 | 11 | 11 | 9 | 35 | 40 | 24 | 12 | 13 | 17 | 0 | 18 | 8 |
19.2.4.2 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction | 528 | 37 | 8 | 10 | 8 | 12 | 9 | 11 | 14 | 12 | 5 | 14 | 17 | 18 | 15 | 5 | 8 | 0 | 11 | 11 | 11 | 11 | 10 | 14 | 8 | 12 | 17 | 13 | 14 | 10 | 16 | 10 | 40 | 58 | 36 | 10 | 9 | 16 | 0 | 18 | 7 |
19.1.1.2 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system | 527 | 37 | 12 | 13 | 11 | 10 | 10 | 11 | 25 | 12 | 7 | 16 | 13 | 11 | 16 | 7 | 9 | 0 | 11 | 12 | 12 | 10 | 10 | 15 | 9 | 15 | 15 | 14 | 14 | 10 | 20 | 12 | 41 | 33 | 17 | 10 | 13 | 20 | 0 | 20 | 11 |
19.2.2.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.MUB conjugation | 524 | 37 | 17 | 14 | 11 | 14 | 9 | 10 | 21 | 8 | 3 | 18 | 9 | 11 | 35 | 3 | 4 | 0 | 11 | 12 | 11 | 9 | 14 | 17 | 13 | 10 | 18 | 11 | 10 | 17 | 9 | 9 | 36 | 36 | 23 | 12 | 16 | 16 | 0 | 16 | 11 |
19.3.3 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system | 522 | 37 | 17 | 18 | 7 | 17 | 10 | 11 | 19 | 15 | 6 | 13 | 9 | 11 | 18 | 5 | 8 | 0 | 11 | 14 | 11 | 9 | 10 | 13 | 13 | 14 | 21 | 11 | 11 | 14 | 18 | 10 | 43 | 31 | 13 | 12 | 12 | 19 | 0 | 16 | 12 |
19.2.2.1.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-conjugating E2 protein (UBC) | 520 | 37 | 12 | 14 | 10 | 12 | 8 | 14 | 21 | 10 | 7 | 20 | 16 | 13 | 23 | 6 | 7 | 0 | 8 | 8 | 7 | 9 | 13 | 20 | 10 | 11 | 16 | 11 | 13 | 16 | 16 | 11 | 29 | 38 | 26 | 12 | 7 | 19 | 0 | 18 | 9 |
19.4.2.3 | Protein homeostasis.proteolysis.serine-type peptidase activities.S1-class protease (Deg) | 490 | 37 | 9 | 10 | 9 | 16 | 10 | 11 | 14 | 9 | 14 | 11 | 11 | 11 | 10 | 10 | 8 | 0 | 10 | 9 | 10 | 10 | 19 | 16 | 11 | 18 | 15 | 11 | 10 | 11 | 22 | 10 | 38 | 31 | 20 | 12 | 10 | 14 | 0 | 13 | 7 |
19.3.2 | Protein homeostasis.autophagy.ATG9-2-18 membrane shuttling complex | 486 | 37 | 9 | 14 | 8 | 11 | 11 | 13 | 24 | 11 | 3 | 11 | 10 | 14 | 16 | 4 | 7 | 0 | 11 | 11 | 10 | 11 | 10 | 13 | 8 | 13 | 16 | 11 | 10 | 12 | 18 | 10 | 36 | 36 | 24 | 11 | 11 | 13 | 0 | 16 | 9 |
19.3.4 | Protein homeostasis.autophagy.autophagic cargo receptor activities | 483 | 37 | 8 | 10 | 8 | 14 | 7 | 12 | 19 | 9 | 3 | 14 | 10 | 10 | 17 | 2 | 11 | 0 | 12 | 10 | 7 | 10 | 21 | 17 | 8 | 12 | 22 | 11 | 11 | 21 | 16 | 7 | 32 | 30 | 20 | 8 | 9 | 20 | 0 | 19 | 6 |
19.2.6.1.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components | 482 | 37 | 7 | 10 | 10 | 12 | 9 | 11 | 22 | 10 | 7 | 14 | 13 | 12 | 15 | 7 | 8 | 0 | 11 | 13 | 12 | 7 | 8 | 17 | 9 | 20 | 15 | 12 | 10 | 10 | 13 | 8 | 35 | 33 | 22 | 7 | 12 | 16 | 0 | 17 | 8 |
19.4.5.8 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities | 481 | 37 | 10 | 7 | 6 | 12 | 8 | 11 | 11 | 9 | 6 | 13 | 7 | 16 | 14 | 7 | 7 | 0 | 10 | 10 | 11 | 9 | 4 | 16 | 8 | 17 | 15 | 11 | 11 | 13 | 17 | 8 | 38 | 60 | 29 | 6 | 15 | 10 | 0 | 10 | 9 |
19.2.6.1.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components | 478 | 37 | 11 | 10 | 8 | 11 | 8 | 10 | 18 | 13 | 8 | 14 | 10 | 11 | 13 | 7 | 7 | 0 | 11 | 10 | 10 | 11 | 13 | 15 | 10 | 14 | 14 | 11 | 12 | 9 | 16 | 8 | 37 | 27 | 18 | 9 | 15 | 17 | 0 | 17 | 15 |
19.2.2.8.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.BTB/POZ substrate adaptor components | 473 | 35 | 13 | 7 | 8 | 11 | 13 | 15 | 18 | 6 | 0 | 18 | 13 | 19 | 18 | 0 | 3 | 0 | 7 | 9 | 9 | 8 | 14 | 11 | 9 | 6 | 14 | 9 | 9 | 15 | 6 | 4 | 35 | 65 | 41 | 8 | 5 | 11 | 0 | 11 | 5 |
19.2.2.1.5.3.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities.RING-v-class E3 ligase | 461 | 36 | 9 | 11 | 10 | 13 | 5 | 12 | 15 | 10 | 1 | 14 | 13 | 12 | 24 | 0 | 1 | 0 | 11 | 14 | 14 | 10 | 12 | 18 | 8 | 3 | 17 | 11 | 12 | 15 | 10 | 7 | 32 | 33 | 25 | 12 | 8 | 15 | 0 | 13 | 11 |
19.2.6.2.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components | 459 | 37 | 12 | 10 | 5 | 11 | 8 | 14 | 13 | 12 | 6 | 13 | 10 | 11 | 16 | 6 | 6 | 0 | 9 | 11 | 11 | 9 | 6 | 15 | 8 | 16 | 16 | 10 | 12 | 10 | 18 | 9 | 36 | 38 | 22 | 10 | 12 | 7 | 0 | 8 | 13 |
19.2.1.2.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.N-terminal modification | 453 | 37 | 13 | 8 | 7 | 9 | 6 | 11 | 18 | 14 | 3 | 16 | 8 | 11 | 20 | 2 | 4 | 0 | 13 | 16 | 14 | 15 | 13 | 13 | 7 | 6 | 13 | 15 | 16 | 9 | 10 | 7 | 33 | 27 | 20 | 10 | 10 | 13 | 0 | 13 | 10 |
19.3.2.1 | Protein homeostasis.autophagy.ATG9-2-18 membrane shuttling complex.components | 441 | 37 | 8 | 13 | 7 | 10 | 10 | 12 | 22 | 10 | 3 | 10 | 9 | 13 | 15 | 4 | 6 | 0 | 10 | 10 | 9 | 10 | 9 | 12 | 7 | 11 | 15 | 10 | 9 | 11 | 16 | 8 | 32 | 33 | 22 | 10 | 10 | 12 | 0 | 15 | 8 |
19.2.3.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin | 426 | 37 | 11 | 9 | 8 | 10 | 8 | 9 | 16 | 8 | 8 | 14 | 17 | 8 | 14 | 8 | 8 | 0 | 8 | 8 | 8 | 7 | 12 | 13 | 9 | 13 | 18 | 8 | 8 | 11 | 14 | 9 | 23 | 26 | 18 | 11 | 10 | 14 | 0 | 13 | 9 |
19.2.3.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex | 426 | 37 | 11 | 9 | 8 | 10 | 8 | 9 | 16 | 8 | 8 | 14 | 17 | 8 | 14 | 8 | 8 | 0 | 8 | 8 | 8 | 7 | 12 | 13 | 9 | 13 | 18 | 8 | 8 | 11 | 14 | 9 | 23 | 26 | 18 | 11 | 10 | 14 | 0 | 13 | 9 |
19.1.2 | Protein homeostasis.protein quality control.ribosome-associated chaperone activities | 421 | 37 | 7 | 7 | 5 | 10 | 5 | 8 | 13 | 10 | 4 | 13 | 22 | 9 | 15 | 5 | 4 | 0 | 8 | 10 | 8 | 4 | 13 | 12 | 8 | 15 | 11 | 9 | 9 | 9 | 10 | 6 | 34 | 36 | 26 | 5 | 10 | 17 | 0 | 18 | 6 |
19.4.1.7 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C97-class peptidase (PPPDE) | 406 | 37 | 8 | 9 | 7 | 10 | 7 | 10 | 12 | 10 | 3 | 16 | 9 | 12 | 19 | 4 | 4 | 0 | 9 | 10 | 9 | 8 | 6 | 10 | 12 | 7 | 16 | 11 | 11 | 10 | 9 | 7 | 37 | 28 | 16 | 8 | 9 | 13 | 0 | 13 | 7 |
19.1.1.1 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system | 395 | 37 | 9 | 9 | 9 | 9 | 8 | 9 | 12 | 9 | 3 | 15 | 8 | 9 | 14 | 4 | 6 | 0 | 9 | 10 | 8 | 8 | 8 | 17 | 11 | 10 | 14 | 9 | 9 | 9 | 17 | 6 | 28 | 27 | 19 | 9 | 6 | 9 | 0 | 10 | 9 |
19.2.2.1.5.3.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities.E3 ubiquitin ligase (SINA) | 379 | 35 | 12 | 11 | 6 | 15 | 5 | 12 | 14 | 8 | 0 | 4 | 11 | 13 | 15 | 0 | 2 | 0 | 7 | 7 | 8 | 11 | 7 | 10 | 5 | 4 | 14 | 8 | 8 | 13 | 4 | 5 | 30 | 45 | 25 | 10 | 8 | 9 | 0 | 9 | 4 |
19.4.5.7 | Protein homeostasis.proteolysis.metallopeptidase activities.carboxypeptidase activities | 376 | 37 | 9 | 6 | 8 | 7 | 7 | 10 | 16 | 7 | 5 | 8 | 17 | 10 | 7 | 4 | 5 | 0 | 9 | 8 | 8 | 9 | 20 | 10 | 9 | 11 | 10 | 7 | 8 | 8 | 20 | 6 | 16 | 27 | 21 | 10 | 7 | 10 | 0 | 10 | 6 |
19.4.2.4 | Protein homeostasis.proteolysis.serine-type peptidase activities.S16-class protease (LON) | 363 | 37 | 7 | 8 | 6 | 9 | 5 | 8 | 13 | 8 | 3 | 7 | 9 | 8 | 7 | 5 | 5 | 0 | 9 | 8 | 9 | 9 | 13 | 11 | 5 | 14 | 11 | 9 | 9 | 6 | 11 | 8 | 29 | 29 | 16 | 5 | 8 | 15 | 0 | 14 | 7 |
19.2.2.1.5.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.HECT-type E3 ligase activities | 361 | 37 | 9 | 10 | 7 | 7 | 6 | 10 | 10 | 10 | 3 | 13 | 8 | 8 | 10 | 3 | 6 | 0 | 8 | 8 | 6 | 6 | 12 | 15 | 7 | 13 | 13 | 9 | 11 | 14 | 10 | 8 | 22 | 23 | 16 | 8 | 4 | 11 | 0 | 12 | 5 |
19.2.2.1.5.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.HECT-type E3 ligase activities.monomeric E3 ubiquitin ligase (HECT) | 361 | 37 | 9 | 10 | 7 | 7 | 6 | 10 | 10 | 10 | 3 | 13 | 8 | 8 | 10 | 3 | 6 | 0 | 8 | 8 | 6 | 6 | 12 | 15 | 7 | 13 | 13 | 9 | 11 | 14 | 10 | 8 | 22 | 23 | 16 | 8 | 4 | 11 | 0 | 12 | 5 |
19.1.6.1 | Protein homeostasis.protein quality control.Hsp90 chaperone system.chaperone (Hsp90) | 354 | 37 | 8 | 7 | 6 | 7 | 4 | 8 | 27 | 9 | 3 | 5 | 6 | 9 | 11 | 4 | 5 | 0 | 9 | 9 | 9 | 8 | 11 | 10 | 6 | 14 | 11 | 7 | 9 | 7 | 9 | 6 | 30 | 18 | 12 | 8 | 11 | 12 | 0 | 13 | 6 |
19.2.1.3 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway | 346 | 37 | 7 | 8 | 6 | 14 | 6 | 7 | 11 | 7 | 6 | 12 | 8 | 11 | 10 | 1 | 8 | 0 | 6 | 7 | 7 | 7 | 10 | 13 | 6 | 15 | 11 | 6 | 6 | 8 | 13 | 6 | 16 | 27 | 17 | 7 | 6 | 11 | 0 | 12 | 7 |
19.2.1.3.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex | 346 | 37 | 7 | 8 | 6 | 14 | 6 | 7 | 11 | 7 | 6 | 12 | 8 | 11 | 10 | 1 | 8 | 0 | 6 | 7 | 7 | 7 | 10 | 13 | 6 | 15 | 11 | 6 | 6 | 8 | 13 | 6 | 16 | 27 | 17 | 7 | 6 | 11 | 0 | 12 | 7 |
19.2.2.5.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.MUB conjugation.conjugation E2 protein | 345 | 37 | 11 | 10 | 8 | 8 | 6 | 7 | 14 | 5 | 2 | 11 | 6 | 8 | 23 | 2 | 3 | 0 | 7 | 8 | 7 | 6 | 7 | 12 | 8 | 7 | 11 | 7 | 6 | 12 | 7 | 6 | 23 | 27 | 17 | 7 | 11 | 9 | 0 | 9 | 7 |
19.2.4.1 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).HRD1 E3 ubiquitin ligase complex | 341 | 37 | 7 | 12 | 6 | 9 | 6 | 7 | 15 | 7 | 5 | 10 | 6 | 7 | 12 | 5 | 6 | 0 | 6 | 6 | 6 | 7 | 8 | 8 | 6 | 12 | 14 | 7 | 7 | 9 | 10 | 6 | 22 | 23 | 13 | 7 | 9 | 14 | 0 | 15 | 6 |
19.3.1 | Protein homeostasis.autophagy.ATG1-13 autophagosome assembly control complex | 341 | 37 | 10 | 7 | 7 | 8 | 7 | 8 | 12 | 8 | 3 | 8 | 8 | 8 | 9 | 3 | 4 | 0 | 7 | 8 | 8 | 7 | 7 | 9 | 7 | 9 | 14 | 8 | 9 | 8 | 11 | 5 | 21 | 23 | 15 | 8 | 9 | 16 | 0 | 18 | 4 |
19.1.7.1 | Protein homeostasis.protein quality control.Hsp60 chaperone system.chaperone (Hsp60) | 337 | 37 | 8 | 8 | 8 | 9 | 6 | 9 | 7 | 9 | 4 | 8 | 9 | 8 | 10 | 3 | 3 | 0 | 8 | 8 | 7 | 5 | 4 | 13 | 3 | 10 | 10 | 9 | 9 | 9 | 14 | 9 | 26 | 30 | 20 | 7 | 1 | 10 | 0 | 9 | 7 |
19.4.2.1.1 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT1) | 337 | 31 | 6 | 0 | 8 | 9 | 10 | 12 | 11 | 5 | 0 | 0 | 14 | 7 | 15 | 0 | 1 | 0 | 7 | 12 | 9 | 0 | 8 | 4 | 7 | 3 | 18 | 10 | 13 | 26 | 4 | 10 | 27 | 38 | 15 | 6 | 0 | 11 | 0 | 6 | 5 |
19.2.3.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.SUMO deconjugation | 336 | 37 | 5 | 8 | 6 | 9 | 5 | 12 | 8 | 8 | 2 | 10 | 11 | 12 | 9 | 3 | 3 | 0 | 10 | 9 | 10 | 6 | 6 | 8 | 6 | 12 | 11 | 13 | 10 | 9 | 10 | 6 | 19 | 33 | 18 | 5 | 2 | 8 | 0 | 6 | 8 |
19.2.2.1.5.4.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RBR-type E3 ligase activities.plant-specific E3 ubiquitin ligase (RSL/RFA) | 330 | 36 | 5 | 4 | 4 | 20 | 7 | 9 | 4 | 11 | 3 | 4 | 4 | 12 | 7 | 0 | 2 | 0 | 6 | 10 | 9 | 7 | 8 | 7 | 3 | 4 | 10 | 10 | 11 | 9 | 7 | 1 | 34 | 48 | 23 | 5 | 4 | 7 | 0 | 7 | 4 |
19.2.2.8.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes | 326 | 37 | 8 | 6 | 5 | 9 | 6 | 9 | 6 | 2 | 4 | 12 | 5 | 8 | 12 | 4 | 6 | 0 | 6 | 6 | 7 | 5 | 7 | 8 | 9 | 21 | 13 | 7 | 7 | 11 | 12 | 7 | 18 | 21 | 16 | 8 | 2 | 13 | 0 | 11 | 9 |
19.2.1.2.1.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.N-terminal modification.cysteine oxidase (PCO) | 324 | 37 | 9 | 5 | 4 | 5 | 3 | 8 | 15 | 11 | 1 | 13 | 6 | 7 | 17 | 1 | 1 | 0 | 10 | 13 | 11 | 11 | 9 | 10 | 5 | 4 | 9 | 11 | 13 | 6 | 4 | 4 | 24 | 18 | 13 | 7 | 10 | 10 | 0 | 10 | 6 |
19.3.2.1.3 | Protein homeostasis.autophagy.ATG9-2-18 membrane shuttling complex.components.component ATG18 | 314 | 37 | 6 | 11 | 5 | 8 | 7 | 9 | 18 | 6 | 2 | 6 | 6 | 9 | 10 | 2 | 4 | 0 | 7 | 7 | 6 | 7 | 6 | 8 | 5 | 8 | 11 | 7 | 6 | 9 | 12 | 6 | 18 | 24 | 15 | 8 | 9 | 9 | 0 | 12 | 5 |
19.1.4 | Protein homeostasis.protein quality control.plastidial Hsp70 chaperone system | 310 | 37 | 8 | 11 | 8 | 8 | 6 | 6 | 9 | 6 | 4 | 9 | 6 | 7 | 11 | 2 | 5 | 0 | 7 | 7 | 8 | 3 | 6 | 11 | 6 | 14 | 9 | 7 | 7 | 7 | 15 | 8 | 17 | 20 | 13 | 6 | 5 | 11 | 0 | 11 | 6 |
19.1.2.1 | Protein homeostasis.protein quality control.ribosome-associated chaperone activities.NAC chaperone heterodimer | 309 | 37 | 5 | 5 | 3 | 7 | 3 | 6 | 10 | 8 | 2 | 10 | 20 | 7 | 13 | 3 | 2 | 0 | 6 | 8 | 6 | 2 | 9 | 9 | 6 | 11 | 9 | 6 | 7 | 6 | 6 | 4 | 24 | 30 | 22 | 4 | 9 | 9 | 0 | 9 | 3 |
19.4.5.6.6 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M20-class IAA-amino acid hydrolase | 306 | 37 | 4 | 6 | 5 | 7 | 6 | 8 | 11 | 8 | 2 | 8 | 7 | 10 | 8 | 2 | 1 | 0 | 8 | 8 | 9 | 2 | 7 | 9 | 6 | 3 | 9 | 10 | 12 | 7 | 6 | 6 | 25 | 31 | 16 | 8 | 9 | 9 | 0 | 9 | 4 |
19.2.2.1.5.4.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RBR-type E3 ligase activities.E3 ubiquitin ligase (RBR-Ariadne) | 304 | 37 | 4 | 6 | 3 | 15 | 2 | 9 | 5 | 7 | 2 | 5 | 12 | 8 | 7 | 1 | 5 | 0 | 8 | 9 | 9 | 8 | 7 | 9 | 3 | 6 | 7 | 12 | 9 | 6 | 6 | 4 | 27 | 31 | 17 | 4 | 7 | 10 | 0 | 12 | 2 |
19.4.5.8.1 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH mitochondrial protease complexes | 302 | 37 | 6 | 3 | 4 | 6 | 5 | 7 | 7 | 5 | 4 | 8 | 5 | 12 | 9 | 4 | 4 | 0 | 6 | 6 | 7 | 6 | 2 | 11 | 5 | 8 | 7 | 7 | 7 | 9 | 9 | 3 | 24 | 48 | 22 | 3 | 8 | 6 | 0 | 4 | 5 |
19.2.3.1.2.7 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.deubiquitinase (OTU6-12) | 288 | 37 | 7 | 7 | 6 | 7 | 5 | 9 | 7 | 6 | 3 | 7 | 8 | 8 | 10 | 3 | 3 | 0 | 7 | 8 | 6 | 7 | 1 | 10 | 6 | 7 | 11 | 7 | 7 | 8 | 6 | 7 | 17 | 23 | 14 | 7 | 8 | 8 | 0 | 10 | 7 |
19.4.2.7 | Protein homeostasis.proteolysis.serine-type peptidase activities.S28-class serine carboxypeptidase | 287 | 37 | 4 | 10 | 3 | 7 | 4 | 5 | 12 | 6 | 2 | 5 | 7 | 7 | 6 | 1 | 4 | 0 | 5 | 5 | 5 | 5 | 17 | 9 | 5 | 2 | 16 | 7 | 5 | 6 | 10 | 3 | 19 | 27 | 14 | 11 | 5 | 16 | 0 | 10 | 2 |
19.1.1.2.1 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.ERdj3B-BiP-SDF2 chaperone complex | 281 | 37 | 7 | 7 | 6 | 5 | 4 | 6 | 16 | 6 | 3 | 10 | 5 | 7 | 10 | 4 | 4 | 0 | 6 | 6 | 6 | 5 | 4 | 6 | 3 | 8 | 8 | 7 | 7 | 5 | 10 | 5 | 25 | 18 | 11 | 4 | 8 | 11 | 0 | 11 | 7 |
19.2.2.1.6.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).polyubiquitination.ligating E3 protein (RGLG) | 276 | 36 | 7 | 5 | 3 | 5 | 4 | 6 | 20 | 6 | 1 | 9 | 5 | 7 | 11 | 0 | 2 | 0 | 6 | 7 | 7 | 4 | 11 | 9 | 5 | 4 | 11 | 8 | 7 | 4 | 4 | 4 | 23 | 25 | 14 | 6 | 5 | 7 | 0 | 9 | 5 |
19.4.5.7.3 | Protein homeostasis.proteolysis.metallopeptidase activities.carboxypeptidase activities.M28-class carboxypeptidase | 273 | 37 | 7 | 4 | 7 | 5 | 5 | 8 | 14 | 5 | 1 | 5 | 15 | 8 | 5 | 2 | 3 | 0 | 7 | 6 | 6 | 7 | 13 | 6 | 7 | 7 | 6 | 5 | 6 | 6 | 16 | 4 | 9 | 21 | 18 | 8 | 5 | 6 | 0 | 6 | 4 |
19.1.3 | Protein homeostasis.protein quality control.mitochondrial Hsp70 chaperone system | 268 | 37 | 8 | 8 | 6 | 6 | 7 | 8 | 8 | 6 | 2 | 9 | 8 | 8 | 9 | 3 | 3 | 0 | 7 | 7 | 6 | 3 | 3 | 10 | 5 | 8 | 7 | 7 | 8 | 6 | 10 | 5 | 15 | 21 | 14 | 4 | 2 | 8 | 0 | 7 | 6 |
19.2.2.1.6.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).polyubiquitination.Ubc13-Uev1 conjugating E2 complex | 261 | 37 | 7 | 7 | 6 | 8 | 5 | 5 | 9 | 5 | 2 | 10 | 7 | 7 | 11 | 2 | 2 | 0 | 7 | 6 | 6 | 6 | 10 | 8 | 6 | 7 | 8 | 6 | 6 | 7 | 7 | 5 | 12 | 15 | 10 | 6 | 8 | 10 | 0 | 9 | 3 |
19.1.5.1 | Protein homeostasis.protein quality control.cytosolic Hsp70 chaperone system.chaperone (Hsp70) | 256 | 35 | 6 | 6 | 6 | 7 | 0 | 7 | 6 | 7 | 1 | 4 | 6 | 8 | 12 | 1 | 2 | 0 | 7 | 7 | 8 | 1 | 5 | 9 | 4 | 7 | 12 | 7 | 7 | 9 | 8 | 7 | 16 | 29 | 15 | 1 | 4 | 5 | 0 | 0 | 9 |
19.2.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).ubiquitin-fold protein (SUMO) | 255 | 37 | 7 | 6 | 5 | 9 | 2 | 9 | 4 | 12 | 8 | 3 | 3 | 12 | 5 | 1 | 2 | 0 | 6 | 8 | 4 | 5 | 3 | 4 | 11 | 6 | 5 | 9 | 6 | 6 | 6 | 3 | 15 | 36 | 12 | 6 | 5 | 5 | 0 | 4 | 2 |
19.2.2.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-fold protein (UBQ) | 245 | 30 | 1 | 0 | 2 | 9 | 0 | 7 | 0 | 0 | 1 | 0 | 13 | 15 | 5 | 1 | 5 | 0 | 4 | 5 | 7 | 0 | 28 | 6 | 5 | 9 | 10 | 10 | 10 | 3 | 11 | 1 | 5 | 42 | 17 | 3 | 0 | 4 | 0 | 2 | 4 |
19.1.8.1 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-I protein | 240 | 30 | 3 | 5 | 5 | 6 | 8 | 6 | 13 | 4 | 0 | 12 | 5 | 11 | 10 | 0 | 0 | 0 | 3 | 7 | 4 | 6 | 5 | 3 | 4 | 0 | 12 | 7 | 7 | 5 | 0 | 10 | 17 | 33 | 8 | 0 | 7 | 7 | 0 | 7 | 0 |
19.1.1.1.1 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system.CNX-CRT cycle | 231 | 37 | 5 | 5 | 6 | 5 | 4 | 5 | 9 | 5 | 2 | 10 | 5 | 5 | 9 | 2 | 2 | 0 | 5 | 6 | 5 | 4 | 5 | 9 | 6 | 7 | 9 | 5 | 5 | 5 | 8 | 3 | 17 | 15 | 11 | 5 | 5 | 6 | 0 | 6 | 5 |
19.4.5.6.5 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M1-class neutral/aromatic-hydroxyl amino acid aminopeptidase | 230 | 37 | 5 | 4 | 3 | 3 | 3 | 5 | 9 | 5 | 3 | 6 | 6 | 8 | 6 | 3 | 3 | 0 | 6 | 5 | 6 | 5 | 2 | 10 | 3 | 4 | 7 | 5 | 5 | 3 | 16 | 3 | 19 | 22 | 12 | 4 | 6 | 5 | 0 | 6 | 4 |
19.2.2.8.1.4.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component SKP2 | 229 | 35 | 5 | 4 | 4 | 6 | 6 | 5 | 7 | 4 | 0 | 9 | 4 | 5 | 7 | 0 | 6 | 0 | 4 | 4 | 3 | 6 | 18 | 6 | 6 | 4 | 8 | 6 | 6 | 5 | 7 | 5 | 10 | 17 | 10 | 2 | 9 | 7 | 0 | 7 | 7 |
19.1.5.5 | Protein homeostasis.protein quality control.cytosolic Hsp70 chaperone system.nucleotide exchange factor (BAG) | 220 | 35 | 4 | 6 | 5 | 4 | 4 | 5 | 9 | 5 | 0 | 8 | 6 | 6 | 10 | 0 | 1 | 0 | 5 | 5 | 5 | 5 | 3 | 8 | 4 | 2 | 8 | 5 | 5 | 5 | 4 | 3 | 21 | 15 | 10 | 4 | 4 | 12 | 0 | 10 | 4 |
19.4.5.5 | Protein homeostasis.proteolysis.metallopeptidase activities.M48 families | 220 | 37 | 3 | 3 | 3 | 3 | 3 | 12 | 5 | 5 | 4 | 4 | 3 | 11 | 4 | 2 | 4 | 0 | 3 | 4 | 4 | 5 | 7 | 2 | 3 | 3 | 5 | 3 | 3 | 3 | 5 | 4 | 9 | 40 | 13 | 3 | 2 | 14 | 0 | 13 | 3 |
19.2.2.3.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB maturation | 218 | 37 | 3 | 5 | 3 | 4 | 4 | 6 | 5 | 7 | 3 | 6 | 6 | 6 | 4 | 3 | 3 | 0 | 6 | 8 | 7 | 4 | 1 | 7 | 3 | 3 | 4 | 9 | 7 | 4 | 6 | 2 | 22 | 20 | 12 | 3 | 4 | 6 | 0 | 8 | 4 |
19.3.3.1 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ubiquitin-fold protein (ATG8) | 212 | 37 | 9 | 10 | 3 | 9 | 3 | 4 | 10 | 9 | 1 | 6 | 3 | 4 | 10 | 1 | 2 | 0 | 5 | 5 | 4 | 3 | 1 | 4 | 6 | 7 | 11 | 4 | 4 | 7 | 6 | 4 | 21 | 9 | 2 | 6 | 4 | 6 | 0 | 5 | 4 |
19.4.2.8 | Protein homeostasis.proteolysis.serine-type peptidase activities.mitochondrion Clp-type protease complex | 211 | 37 | 4 | 4 | 4 | 4 | 2 | 5 | 10 | 5 | 5 | 6 | 4 | 4 | 5 | 3 | 3 | 0 | 5 | 5 | 5 | 4 | 8 | 7 | 5 | 8 | 5 | 5 | 5 | 6 | 14 | 3 | 13 | 12 | 8 | 5 | 6 | 5 | 0 | 6 | 3 |
19.4.1.3 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C13-class asparaginyl endopeptidase (Legumain) | 206 | 35 | 3 | 2 | 4 | 4 | 4 | 4 | 4 | 4 | 1 | 0 | 6 | 9 | 8 | 0 | 1 | 0 | 4 | 5 | 5 | 4 | 6 | 8 | 2 | 4 | 6 | 4 | 4 | 16 | 4 | 2 | 10 | 29 | 15 | 4 | 5 | 5 | 0 | 5 | 5 |
19.2.4.4 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).delivery to proteasome | 200 | 37 | 4 | 7 | 5 | 5 | 3 | 6 | 8 | 5 | 2 | 4 | 4 | 5 | 7 | 2 | 2 | 0 | 5 | 5 | 5 | 5 | 4 | 8 | 4 | 8 | 8 | 5 | 4 | 5 | 4 | 5 | 14 | 12 | 7 | 4 | 4 | 6 | 0 | 6 | 3 |
19.2.1.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Ac/N-degron pathway | 195 | 37 | 5 | 4 | 3 | 5 | 3 | 4 | 5 | 3 | 2 | 5 | 6 | 8 | 6 | 2 | 3 | 0 | 3 | 4 | 3 | 2 | 5 | 5 | 3 | 7 | 5 | 3 | 4 | 4 | 6 | 4 | 10 | 22 | 20 | 4 | 4 | 5 | 0 | 5 | 3 |
19.2.1.1.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Ac/N-degron pathway.Doa10 E3 ubiquitin ligase complex | 195 | 37 | 5 | 4 | 3 | 5 | 3 | 4 | 5 | 3 | 2 | 5 | 6 | 8 | 6 | 2 | 3 | 0 | 3 | 4 | 3 | 2 | 5 | 5 | 3 | 7 | 5 | 3 | 4 | 4 | 6 | 4 | 10 | 22 | 20 | 4 | 4 | 5 | 0 | 5 | 3 |
19.4.2.9.1 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.proteolytic core component ClpP1|3-6 | 195 | 37 | 5 | 5 | 3 | 5 | 3 | 5 | 6 | 4 | 2 | 5 | 14 | 4 | 4 | 2 | 4 | 0 | 4 | 6 | 5 | 4 | 3 | 2 | 6 | 10 | 6 | 4 | 4 | 5 | 8 | 4 | 11 | 12 | 9 | 4 | 2 | 6 | 0 | 4 | 5 |
19.2.4.2.1 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction.platform ATPase (CDC48) | 193 | 35 | 0 | 3 | 3 | 3 | 2 | 4 | 4 | 4 | 1 | 4 | 10 | 11 | 4 | 2 | 3 | 0 | 4 | 3 | 3 | 4 | 0 | 4 | 1 | 6 | 5 | 5 | 5 | 5 | 4 | 2 | 15 | 34 | 19 | 3 | 2 | 5 | 0 | 4 | 2 |
19.2.4.3 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate processing | 191 | 37 | 3 | 4 | 4 | 4 | 4 | 3 | 10 | 3 | 4 | 5 | 4 | 6 | 6 | 2 | 4 | 0 | 4 | 4 | 4 | 4 | 7 | 5 | 2 | 5 | 8 | 4 | 4 | 5 | 10 | 4 | 10 | 13 | 10 | 4 | 2 | 6 | 0 | 5 | 5 |
19.2.2.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.UFM conjugation | 190 | 36 | 5 | 5 | 4 | 4 | 4 | 4 | 7 | 4 | 3 | 4 | 7 | 4 | 7 | 0 | 4 | 0 | 5 | 4 | 4 | 5 | 3 | 7 | 6 | 4 | 5 | 4 | 4 | 5 | 8 | 4 | 11 | 15 | 6 | 4 | 7 | 4 | 0 | 5 | 4 |
19.2.2.8.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.BTB/POZ substrate adaptor components.component LRB | 190 | 35 | 3 | 2 | 1 | 3 | 8 | 9 | 5 | 2 | 0 | 5 | 9 | 12 | 4 | 0 | 1 | 0 | 2 | 2 | 2 | 2 | 9 | 4 | 1 | 2 | 4 | 2 | 2 | 5 | 2 | 1 | 10 | 38 | 25 | 3 | 1 | 3 | 0 | 3 | 3 |
19.2.2.1.7 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin receptor regulatory protein (DA1) | 187 | 37 | 4 | 4 | 3 | 8 | 2 | 5 | 5 | 4 | 1 | 4 | 4 | 4 | 7 | 1 | 1 | 0 | 4 | 4 | 4 | 5 | 3 | 7 | 4 | 9 | 7 | 4 | 4 | 5 | 4 | 3 | 20 | 13 | 8 | 4 | 4 | 5 | 0 | 6 | 3 |
19.4.5.6.1 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M24-class methionyl aminopeptidase (MAP1) | 186 | 37 | 5 | 3 | 4 | 4 | 4 | 5 | 5 | 5 | 2 | 4 | 5 | 5 | 5 | 4 | 2 | 0 | 5 | 5 | 5 | 5 | 3 | 1 | 4 | 5 | 3 | 5 | 5 | 3 | 6 | 3 | 18 | 18 | 13 | 3 | 2 | 3 | 0 | 6 | 3 |
19.4.2.1.5 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT5) | 184 | 32 | 5 | 3 | 4 | 6 | 4 | 7 | 6 | 3 | 0 | 0 | 4 | 6 | 7 | 0 | 1 | 0 | 1 | 6 | 8 | 0 | 4 | 1 | 2 | 2 | 15 | 6 | 8 | 6 | 4 | 9 | 11 | 14 | 13 | 7 | 0 | 5 | 0 | 3 | 3 |
19.4.5.4 | Protein homeostasis.proteolysis.metallopeptidase activities.M16 families | 182 | 37 | 5 | 3 | 2 | 5 | 6 | 4 | 5 | 3 | 3 | 3 | 4 | 4 | 3 | 2 | 3 | 0 | 5 | 7 | 7 | 4 | 5 | 9 | 3 | 9 | 2 | 4 | 4 | 4 | 6 | 3 | 13 | 12 | 8 | 4 | 2 | 6 | 0 | 6 | 4 |
19.2.2.5.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.MUB conjugation.ubiquitin-fold protein (MUB) | 179 | 37 | 6 | 4 | 3 | 6 | 3 | 3 | 7 | 3 | 1 | 7 | 3 | 3 | 12 | 1 | 1 | 0 | 4 | 4 | 4 | 3 | 7 | 5 | 5 | 3 | 7 | 4 | 4 | 5 | 2 | 3 | 13 | 9 | 6 | 5 | 5 | 7 | 0 | 7 | 4 |
19.4.5.8.2 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH plastidial protease complexes | 179 | 37 | 4 | 4 | 2 | 6 | 3 | 4 | 4 | 4 | 2 | 5 | 2 | 4 | 5 | 3 | 3 | 0 | 4 | 4 | 4 | 3 | 2 | 5 | 3 | 9 | 8 | 4 | 4 | 4 | 8 | 5 | 14 | 12 | 7 | 3 | 7 | 4 | 0 | 6 | 4 |
19.2.4.2.2 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction.NPL4-UFD1 CDC48-cofactor heterodimer | 178 | 37 | 3 | 2 | 2 | 5 | 4 | 4 | 4 | 5 | 2 | 5 | 5 | 4 | 5 | 1 | 2 | 0 | 4 | 5 | 5 | 4 | 5 | 6 | 3 | 2 | 5 | 5 | 6 | 2 | 4 | 3 | 17 | 15 | 11 | 2 | 3 | 7 | 0 | 9 | 2 |
19.4.5.3 | Protein homeostasis.proteolysis.metallopeptidase activities.M10-class metalloprotease (Matrixin) | 178 | 36 | 3 | 3 | 2 | 5 | 2 | 4 | 2 | 4 | 1 | 2 | 4 | 4 | 4 | 0 | 1 | 0 | 4 | 4 | 4 | 4 | 10 | 2 | 2 | 2 | 24 | 4 | 5 | 6 | 4 | 2 | 7 | 13 | 5 | 8 | 5 | 3 | 0 | 3 | 16 |
19.1.2.1.1 | Protein homeostasis.protein quality control.ribosome-associated chaperone activities.NAC chaperone heterodimer.subunit alpha | 170 | 36 | 2 | 2 | 1 | 5 | 2 | 3 | 4 | 6 | 1 | 5 | 7 | 4 | 7 | 2 | 1 | 0 | 4 | 5 | 4 | 0 | 4 | 5 | 4 | 6 | 5 | 3 | 4 | 3 | 2 | 2 | 12 | 23 | 16 | 3 | 4 | 4 | 0 | 4 | 1 |
19.4.2.8.2 | Protein homeostasis.proteolysis.serine-type peptidase activities.mitochondrion Clp-type protease complex.chaperone component ClpX | 169 | 37 | 3 | 3 | 3 | 3 | 1 | 4 | 9 | 4 | 4 | 5 | 3 | 3 | 4 | 2 | 2 | 0 | 4 | 4 | 4 | 4 | 7 | 6 | 3 | 6 | 4 | 4 | 4 | 5 | 10 | 2 | 12 | 9 | 6 | 4 | 6 | 4 | 0 | 6 | 2 |
19.2.2.8.2.2.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.BTB/POZ substrate adaptor components.component BT | 167 | 35 | 6 | 3 | 4 | 5 | 3 | 4 | 7 | 1 | 0 | 8 | 1 | 4 | 9 | 0 | 1 | 0 | 3 | 4 | 4 | 4 | 2 | 4 | 4 | 3 | 6 | 4 | 4 | 6 | 2 | 1 | 14 | 15 | 10 | 3 | 4 | 6 | 0 | 7 | 1 |
19.2.2.1.6.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).polyubiquitination.Ubc13-Uev1 conjugating E2 complex.component Uev1 | 165 | 37 | 5 | 4 | 4 | 5 | 3 | 3 | 6 | 3 | 1 | 5 | 5 | 5 | 7 | 1 | 1 | 0 | 5 | 4 | 4 | 4 | 9 | 7 | 4 | 3 | 4 | 4 | 4 | 3 | 5 | 3 | 9 | 9 | 6 | 3 | 6 | 5 | 0 | 5 | 1 |
19.2.3.1.1.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP5|8-11) | 161 | 35 | 3 | 3 | 3 | 5 | 3 | 4 | 5 | 3 | 1 | 5 | 4 | 4 | 7 | 0 | 2 | 0 | 4 | 4 | 4 | 4 | 4 | 8 | 3 | 0 | 7 | 4 | 4 | 3 | 6 | 4 | 14 | 12 | 8 | 4 | 2 | 3 | 0 | 4 | 3 |
19.2.2.2.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO E3 ligase activities | 159 | 37 | 3 | 4 | 3 | 2 | 2 | 6 | 3 | 4 | 2 | 4 | 5 | 5 | 5 | 1 | 3 | 0 | 5 | 4 | 3 | 4 | 4 | 4 | 1 | 9 | 5 | 3 | 4 | 4 | 2 | 3 | 12 | 15 | 10 | 2 | 5 | 3 | 0 | 3 | 2 |
19.2.3.1.1.7 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP15-21) | 159 | 35 | 4 | 4 | 3 | 5 | 3 | 4 | 7 | 4 | 0 | 5 | 2 | 4 | 9 | 0 | 1 | 0 | 4 | 4 | 4 | 3 | 3 | 3 | 4 | 5 | 7 | 4 | 4 | 4 | 3 | 2 | 10 | 12 | 8 | 5 | 1 | 5 | 0 | 6 | 3 |
19.4.5.8.1.2 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH mitochondrial protease complexes.FtsH3/10 matrix-AAA protease heterodimers | 154 | 37 | 5 | 1 | 2 | 4 | 3 | 3 | 3 | 4 | 2 | 5 | 2 | 4 | 5 | 2 | 2 | 0 | 3 | 4 | 4 | 5 | 2 | 6 | 2 | 5 | 4 | 4 | 4 | 6 | 6 | 2 | 13 | 14 | 9 | 1 | 6 | 3 | 0 | 1 | 3 |
19.1.7.3 | Protein homeostasis.protein quality control.Hsp60 chaperone system.Hsp60-co-chaperone (Hsp10) | 153 | 37 | 3 | 2 | 3 | 4 | 3 | 2 | 3 | 5 | 2 | 2 | 4 | 3 | 5 | 1 | 2 | 0 | 3 | 3 | 3 | 3 | 5 | 4 | 6 | 6 | 6 | 4 | 3 | 3 | 10 | 4 | 12 | 6 | 3 | 4 | 3 | 8 | 0 | 6 | 4 |
19.1.1.1.1.2 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system.CNX-CRT cycle.lectin chaperone (CRT) | 152 | 37 | 4 | 3 | 4 | 3 | 3 | 3 | 6 | 4 | 1 | 7 | 3 | 3 | 5 | 1 | 1 | 0 | 4 | 5 | 4 | 3 | 2 | 6 | 4 | 2 | 6 | 4 | 4 | 3 | 2 | 3 | 14 | 9 | 7 | 4 | 4 | 4 | 0 | 4 | 3 |
19.2.4.4.1 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).delivery to proteasome.shuttle protein (RAD23) | 149 | 37 | 3 | 5 | 3 | 4 | 2 | 5 | 5 | 4 | 1 | 4 | 3 | 4 | 6 | 1 | 1 | 0 | 4 | 4 | 4 | 4 | 2 | 6 | 3 | 6 | 6 | 4 | 3 | 4 | 2 | 4 | 9 | 9 | 5 | 3 | 4 | 5 | 0 | 5 | 2 |
19.4.5.8.1.1 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH mitochondrial protease complexes.component FtsH4|11 | 148 | 36 | 1 | 2 | 2 | 2 | 2 | 4 | 4 | 1 | 2 | 3 | 3 | 8 | 4 | 2 | 2 | 0 | 3 | 2 | 3 | 1 | 0 | 5 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 1 | 11 | 34 | 13 | 2 | 2 | 3 | 0 | 3 | 2 |
19.2.3.1.1.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP12-13) | 146 | 36 | 4 | 4 | 2 | 2 | 1 | 4 | 3 | 4 | 1 | 4 | 5 | 4 | 4 | 0 | 1 | 0 | 4 | 4 | 4 | 3 | 5 | 8 | 2 | 3 | 4 | 4 | 4 | 5 | 4 | 3 | 7 | 11 | 8 | 3 | 2 | 5 | 0 | 7 | 3 |
19.4.1.5 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C26-class gamma-glutamyl peptidase | 145 | 36 | 6 | 2 | 2 | 5 | 7 | 3 | 3 | 3 | 0 | 4 | 3 | 2 | 5 | 1 | 2 | 0 | 3 | 3 | 3 | 4 | 4 | 4 | 4 | 3 | 2 | 4 | 5 | 2 | 4 | 4 | 8 | 15 | 6 | 2 | 3 | 6 | 0 | 4 | 4 |
19.4.2.1.2 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT2) | 145 | 34 | 6 | 3 | 4 | 6 | 3 | 3 | 5 | 3 | 0 | 0 | 3 | 3 | 4 | 0 | 4 | 0 | 3 | 3 | 3 | 3 | 2 | 3 | 1 | 7 | 6 | 4 | 4 | 5 | 7 | 3 | 12 | 10 | 6 | 3 | 1 | 6 | 0 | 4 | 2 |
19.2.2.1.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-activating E1 protein (UBA) | 143 | 37 | 1 | 2 | 3 | 2 | 1 | 4 | 3 | 3 | 1 | 3 | 4 | 4 | 3 | 1 | 2 | 0 | 3 | 4 | 4 | 4 | 7 | 7 | 4 | 4 | 3 | 4 | 4 | 2 | 4 | 2 | 11 | 14 | 9 | 2 | 3 | 5 | 0 | 5 | 1 |
19.4.5.4.2 | Protein homeostasis.proteolysis.metallopeptidase activities.M16 families.peptidase (Nardilysin-like) | 140 | 37 | 3 | 2 | 1 | 4 | 5 | 3 | 4 | 2 | 3 | 2 | 3 | 3 | 2 | 1 | 2 | 0 | 4 | 6 | 6 | 3 | 5 | 6 | 2 | 7 | 2 | 3 | 3 | 3 | 4 | 2 | 10 | 9 | 6 | 3 | 2 | 5 | 0 | 5 | 4 |
19.1.2.1.2 | Protein homeostasis.protein quality control.ribosome-associated chaperone activities.NAC chaperone heterodimer.subunit beta | 139 | 37 | 3 | 3 | 2 | 2 | 1 | 3 | 6 | 2 | 1 | 5 | 13 | 3 | 6 | 1 | 1 | 0 | 2 | 3 | 2 | 2 | 5 | 4 | 2 | 5 | 4 | 3 | 3 | 3 | 4 | 2 | 12 | 7 | 6 | 1 | 5 | 5 | 0 | 5 | 2 |
19.1.8.2 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-II protein | 139 | 34 | 1 | 2 | 2 | 2 | 5 | 1 | 15 | 2 | 0 | 3 | 4 | 1 | 5 | 0 | 10 | 0 | 2 | 1 | 1 | 1 | 3 | 3 | 4 | 3 | 1 | 1 | 2 | 2 | 11 | 2 | 4 | 22 | 7 | 4 | 3 | 5 | 0 | 4 | 0 |
19.2.3.1.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.deubiquitinase (OTU3-4) | 138 | 37 | 3 | 3 | 2 | 2 | 3 | 3 | 5 | 4 | 1 | 4 | 3 | 4 | 3 | 2 | 2 | 0 | 3 | 4 | 4 | 3 | 4 | 3 | 3 | 5 | 6 | 4 | 4 | 2 | 3 | 2 | 9 | 12 | 8 | 4 | 2 | 3 | 0 | 4 | 2 |
19.1.6.2 | Protein homeostasis.protein quality control.Hsp90 chaperone system.Hsp90-co-chaperone (P23) | 137 | 37 | 4 | 4 | 2 | 2 | 2 | 3 | 6 | 3 | 1 | 6 | 2 | 3 | 6 | 1 | 1 | 0 | 3 | 3 | 3 | 2 | 3 | 4 | 4 | 4 | 5 | 3 | 3 | 4 | 4 | 4 | 9 | 10 | 5 | 3 | 5 | 4 | 0 | 4 | 2 |
19.2.2.3.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB ligase E3 activities | 137 | 37 | 3 | 2 | 3 | 3 | 2 | 4 | 4 | 4 | 3 | 4 | 2 | 3 | 5 | 1 | 2 | 0 | 3 | 3 | 3 | 4 | 4 | 4 | 2 | 6 | 4 | 4 | 4 | 4 | 6 | 4 | 10 | 9 | 4 | 3 | 2 | 3 | 0 | 3 | 3 |
19.4.2.9.2 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.non-proteolytic core component ClpR | 137 | 37 | 4 | 4 | 3 | 3 | 3 | 3 | 9 | 3 | 3 | 4 | 3 | 3 | 4 | 3 | 3 | 0 | 3 | 3 | 2 | 2 | 2 | 4 | 3 | 7 | 5 | 3 | 3 | 3 | 7 | 2 | 7 | 9 | 5 | 3 | 2 | 1 | 0 | 3 | 3 |
19.1.5.3 | Protein homeostasis.protein quality control.cytosolic Hsp70 chaperone system.nucleotide exchange factor & co-chaperone (Hsp110) | 136 | 37 | 4 | 3 | 3 | 3 | 2 | 3 | 8 | 3 | 1 | 4 | 3 | 3 | 5 | 1 | 2 | 0 | 3 | 3 | 3 | 3 | 2 | 5 | 2 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 8 | 9 | 6 | 1 | 3 | 6 | 0 | 6 | 5 |
19.2.2.8.3.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.COP1-SPA substrate adaptor subcomplex | 133 | 34 | 4 | 2 | 3 | 4 | 3 | 3 | 2 | 1 | 0 | 5 | 1 | 2 | 7 | 0 | 2 | 0 | 3 | 2 | 3 | 2 | 3 | 2 | 5 | 11 | 7 | 3 | 3 | 6 | 4 | 3 | 6 | 6 | 6 | 4 | 0 | 4 | 0 | 6 | 5 |
19.4.5.8.2.1 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH plastidial protease complexes.component FtsH1|2|5|6|8 | 133 | 37 | 3 | 3 | 1 | 4 | 2 | 3 | 3 | 3 | 2 | 4 | 1 | 3 | 4 | 2 | 2 | 0 | 3 | 3 | 3 | 3 | 1 | 3 | 2 | 7 | 6 | 3 | 3 | 3 | 6 | 4 | 12 | 9 | 5 | 2 | 6 | 2 | 0 | 4 | 3 |
19.1.1.2.1.1 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.ERdj3B-BiP-SDF2 chaperone complex.chaperone component BiP | 132 | 37 | 4 | 3 | 3 | 3 | 2 | 3 | 7 | 3 | 1 | 4 | 3 | 3 | 5 | 1 | 2 | 0 | 3 | 3 | 3 | 3 | 2 | 3 | 1 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 8 | 9 | 6 | 1 | 3 | 6 | 0 | 6 | 5 |
19.4.5.1 | Protein homeostasis.proteolysis.metallopeptidase activities.M3-class metalloprotease | 132 | 36 | 3 | 4 | 4 | 4 | 4 | 3 | 2 | 3 | 1 | 3 | 3 | 3 | 3 | 2 | 3 | 0 | 3 | 3 | 3 | 3 | 0 | 3 | 3 | 3 | 5 | 3 | 3 | 3 | 9 | 3 | 13 | 9 | 6 | 4 | 2 | 2 | 0 | 1 | 3 |
19.2.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO activating E1 heterodimer | 130 | 37 | 3 | 4 | 2 | 4 | 2 | 2 | 13 | 3 | 2 | 4 | 4 | 2 | 3 | 2 | 2 | 0 | 2 | 2 | 2 | 4 | 2 | 4 | 3 | 3 | 4 | 2 | 3 | 3 | 3 | 2 | 9 | 9 | 6 | 2 | 3 | 3 | 0 | 3 | 4 |
19.2.3.1.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP1-2) | 128 | 35 | 1 | 5 | 1 | 2 | 1 | 7 | 4 | 3 | 0 | 2 | 3 | 1 | 1 | 0 | 1 | 0 | 6 | 8 | 4 | 3 | 4 | 3 | 1 | 3 | 2 | 4 | 5 | 2 | 2 | 1 | 8 | 18 | 12 | 1 | 2 | 3 | 0 | 3 | 1 |
19.4.4 | Protein homeostasis.proteolysis.threonine-type peptidase activities | 127 | 37 | 2 | 2 | 2 | 4 | 21 | 2 | 6 | 2 | 1 | 2 | 2 | 4 | 3 | 2 | 1 | 0 | 2 | 3 | 3 | 3 | 2 | 5 | 2 | 2 | 5 | 2 | 3 | 3 | 4 | 3 | 6 | 8 | 4 | 2 | 4 | 2 | 0 | 2 | 1 |
19.4.4.1 | Protein homeostasis.proteolysis.threonine-type peptidase activities.T3-class gamma-glutamyl transpeptidase (GGT) | 127 | 37 | 2 | 2 | 2 | 4 | 21 | 2 | 6 | 2 | 1 | 2 | 2 | 4 | 3 | 2 | 1 | 0 | 2 | 3 | 3 | 3 | 2 | 5 | 2 | 2 | 5 | 2 | 3 | 3 | 4 | 3 | 6 | 8 | 4 | 2 | 4 | 2 | 0 | 2 | 1 |
19.2.1.2.2 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.Arg/N-recognin activities | 126 | 37 | 2 | 5 | 2 | 2 | 2 | 2 | 5 | 2 | 2 | 5 | 2 | 3 | 3 | 2 | 2 | 0 | 4 | 3 | 2 | 2 | 3 | 3 | 2 | 15 | 4 | 2 | 2 | 3 | 4 | 2 | 7 | 9 | 7 | 2 | 3 | 2 | 0 | 2 | 2 |
19.2.2.8.1.4.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component EBF | 126 | 35 | 2 | 3 | 1 | 2 | 2 | 2 | 22 | 2 | 0 | 3 | 5 | 2 | 8 | 0 | 1 | 0 | 2 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | 4 | 2 | 2 | 6 | 2 | 5 | 8 | 6 | 4 | 2 | 3 | 4 | 0 | 4 | 1 |
19.2.2.8.1.4.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component EDL | 126 | 34 | 2 | 3 | 4 | 3 | 2 | 4 | 5 | 2 | 0 | 5 | 1 | 6 | 5 | 0 | 0 | 0 | 3 | 4 | 3 | 4 | 2 | 6 | 4 | 1 | 2 | 4 | 4 | 3 | 2 | 2 | 10 | 10 | 5 | 3 | 2 | 5 | 0 | 4 | 1 |
19.3.1.2 | Protein homeostasis.autophagy.ATG1-13 autophagosome assembly control complex.accessory component ATG13 | 126 | 36 | 2 | 2 | 3 | 2 | 2 | 3 | 5 | 3 | 1 | 4 | 3 | 3 | 3 | 0 | 1 | 0 | 3 | 3 | 3 | 3 | 5 | 2 | 3 | 3 | 5 | 3 | 3 | 2 | 4 | 2 | 10 | 9 | 6 | 1 | 6 | 6 | 0 | 6 | 1 |
19.1.4.2 | Protein homeostasis.protein quality control.plastidial Hsp70 chaperone system.co-chaperone (Hsp40) | 124 | 36 | 4 | 4 | 3 | 4 | 3 | 2 | 3 | 3 | 1 | 2 | 2 | 3 | 5 | 0 | 2 | 0 | 3 | 3 | 4 | 1 | 2 | 4 | 3 | 7 | 4 | 3 | 3 | 3 | 7 | 3 | 3 | 9 | 5 | 2 | 2 | 4 | 0 | 4 | 4 |
19.2.2.1.5.4.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RBR-type E3 ligase activities.E3 ubiquitin ligase (ARA54) | 124 | 36 | 1 | 1 | 1 | 1 | 2 | 3 | 1 | 2 | 1 | 1 | 4 | 10 | 1 | 1 | 1 | 0 | 3 | 6 | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | 5 | 1 | 2 | 1 | 9 | 28 | 17 | 1 | 0 | 1 | 0 | 2 | 1 |
19.1.7.2 | Protein homeostasis.protein quality control.Hsp60 chaperone system.Hsp60-co-chaperone (Hsp20) | 122 | 37 | 2 | 4 | 2 | 1 | 1 | 3 | 3 | 3 | 2 | 3 | 4 | 3 | 4 | 1 | 1 | 0 | 3 | 4 | 3 | 3 | 4 | 4 | 1 | 5 | 2 | 3 | 3 | 2 | 4 | 2 | 12 | 9 | 5 | 2 | 5 | 3 | 0 | 5 | 1 |
19.2.4.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction.NPL4-UFD1 CDC48-cofactor heterodimer.component UFD1 | 120 | 36 | 2 | 1 | 1 | 3 | 3 | 3 | 3 | 4 | 1 | 3 | 2 | 3 | 3 | 0 | 1 | 0 | 3 | 4 | 4 | 3 | 2 | 4 | 2 | 1 | 3 | 4 | 5 | 1 | 2 | 2 | 17 | 12 | 9 | 1 | 1 | 3 | 0 | 3 | 1 |
19.2.2.1.5.3.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities.E3 ubiquitin ligase (DA2) | 119 | 36 | 2 | 6 | 1 | 2 | 2 | 3 | 5 | 2 | 1 | 4 | 5 | 3 | 5 | 1 | 0 | 0 | 3 | 3 | 2 | 3 | 2 | 3 | 2 | 3 | 2 | 3 | 3 | 1 | 2 | 3 | 10 | 8 | 5 | 1 | 5 | 6 | 0 | 6 | 1 |
19.2.2.8.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.scaffold component CUL1/CUL2 | 118 | 36 | 5 | 3 | 2 | 3 | 1 | 3 | 7 | 3 | 1 | 4 | 3 | 3 | 5 | 1 | 1 | 0 | 2 | 3 | 3 | 1 | 0 | 7 | 1 | 3 | 4 | 3 | 3 | 7 | 2 | 2 | 8 | 9 | 5 | 2 | 2 | 2 | 0 | 2 | 2 |
19.2.3.1.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP3-4) | 115 | 37 | 4 | 3 | 2 | 2 | 1 | 3 | 4 | 3 | 1 | 3 | 3 | 3 | 4 | 1 | 1 | 0 | 3 | 3 | 3 | 3 | 2 | 5 | 2 | 3 | 2 | 3 | 3 | 2 | 4 | 2 | 7 | 8 | 6 | 2 | 2 | 4 | 0 | 5 | 3 |
19.3.4.5 | Protein homeostasis.autophagy.autophagic cargo receptor activities.adaptor protein (PUX7/8/9/13) | 115 | 35 | 2 | 3 | 2 | 4 | 2 | 3 | 3 | 3 | 0 | 3 | 3 | 3 | 4 | 0 | 2 | 0 | 3 | 3 | 2 | 3 | 2 | 4 | 2 | 1 | 5 | 3 | 3 | 3 | 4 | 1 | 7 | 9 | 6 | 2 | 3 | 5 | 0 | 5 | 2 |
19.2.2.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO conjugation E2 enzyme (SCE1) | 112 | 35 | 2 | 2 | 2 | 1 | 1 | 3 | 0 | 6 | 3 | 1 | 3 | 5 | 4 | 3 | 1 | 0 | 3 | 3 | 3 | 0 | 3 | 4 | 2 | 2 | 4 | 5 | 4 | 6 | 2 | 2 | 3 | 9 | 6 | 2 | 1 | 7 | 0 | 3 | 1 |
19.2.2.2.4.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO E3 ligase activities.E3 ligase (SIZ1) | 112 | 35 | 2 | 3 | 2 | 1 | 1 | 4 | 3 | 3 | 1 | 3 | 4 | 4 | 4 | 0 | 1 | 0 | 3 | 3 | 2 | 3 | 2 | 4 | 1 | 5 | 4 | 2 | 3 | 3 | 0 | 2 | 9 | 12 | 8 | 1 | 4 | 2 | 0 | 2 | 1 |
19.4.2.9.4 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.chaperone component ClpC | 110 | 36 | 2 | 3 | 1 | 2 | 1 | 4 | 2 | 4 | 0 | 2 | 3 | 4 | 5 | 1 | 1 | 0 | 2 | 4 | 3 | 3 | 1 | 4 | 1 | 5 | 2 | 2 | 4 | 2 | 2 | 3 | 7 | 12 | 8 | 1 | 2 | 2 | 0 | 3 | 2 |
19.2.2.8.1.4.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component ADO | 108 | 33 | 2 | 3 | 3 | 3 | 2 | 3 | 3 | 3 | 0 | 3 | 2 | 3 | 3 | 0 | 1 | 0 | 3 | 3 | 3 | 3 | 0 | 5 | 3 | 0 | 4 | 3 | 3 | 2 | 2 | 3 | 8 | 8 | 5 | 3 | 1 | 5 | 0 | 6 | 1 |
19.2.4.2.4 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction.membrane protein retrotranslocation factor (DFM1) | 108 | 37 | 4 | 4 | 2 | 3 | 2 | 2 | 5 | 2 | 2 | 3 | 2 | 2 | 4 | 2 | 2 | 0 | 2 | 2 | 2 | 2 | 4 | 2 | 3 | 3 | 5 | 2 | 2 | 2 | 4 | 3 | 5 | 6 | 4 | 4 | 2 | 2 | 0 | 4 | 2 |
19.2.2.3.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB activating E1 heterodimer | 107 | 37 | 2 | 2 | 2 | 3 | 2 | 2 | 9 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 0 | 2 | 2 | 2 | 2 | 3 | 4 | 2 | 4 | 4 | 2 | 2 | 3 | 4 | 2 | 5 | 9 | 6 | 2 | 2 | 3 | 0 | 2 | 2 |
19.4.5.5.3 | Protein homeostasis.proteolysis.metallopeptidase activities.M48 families.zinc metalloprotease (OMA1) | 107 | 36 | 1 | 1 | 1 | 1 | 1 | 10 | 2 | 2 | 2 | 1 | 1 | 9 | 1 | 1 | 1 | 0 | 1 | 2 | 2 | 3 | 2 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 4 | 34 | 9 | 1 | 1 | 1 | 0 | 1 | 1 |
19.3.1.1 | Protein homeostasis.autophagy.ATG1-13 autophagosome assembly control complex.kinase component ATG1 | 106 | 36 | 4 | 3 | 2 | 4 | 3 | 3 | 4 | 2 | 1 | 1 | 2 | 3 | 2 | 1 | 1 | 0 | 2 | 3 | 2 | 2 | 0 | 3 | 2 | 3 | 6 | 3 | 3 | 3 | 3 | 1 | 3 | 9 | 5 | 5 | 2 | 4 | 0 | 5 | 1 |
19.1.3.1 | Protein homeostasis.protein quality control.mitochondrial Hsp70 chaperone system.chaperone (mtHsc70) | 105 | 35 | 4 | 3 | 2 | 2 | 2 | 3 | 3 | 3 | 1 | 5 | 5 | 3 | 3 | 1 | 1 | 0 | 2 | 3 | 3 | 0 | 2 | 4 | 2 | 4 | 2 | 2 | 3 | 2 | 2 | 2 | 8 | 10 | 6 | 1 | 0 | 2 | 0 | 2 | 2 |
19.3.4.6 | Protein homeostasis.autophagy.autophagic cargo receptor activities.adaptor protein (DSK2) | 104 | 36 | 1 | 2 | 2 | 2 | 1 | 2 | 7 | 2 | 1 | 4 | 2 | 2 | 5 | 1 | 1 | 0 | 4 | 2 | 2 | 2 | 1 | 4 | 2 | 4 | 3 | 2 | 2 | 9 | 2 | 1 | 7 | 6 | 4 | 2 | 0 | 4 | 0 | 4 | 2 |
19.2.4.1.2 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).HRD1 E3 ubiquitin ligase complex.E2 ubiquitin-conjugating component Ubc7/13/14 | 102 | 37 | 2 | 4 | 2 | 3 | 2 | 2 | 4 | 2 | 1 | 5 | 2 | 2 | 4 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 4 | 2 | 2 | 4 | 2 | 2 | 3 | 6 | 4 | 3 | 2 | 5 | 0 | 6 | 2 |
19.4.2.1.4 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT4) | 102 | 23 | 1 | 2 | 2 | 14 | 3 | 2 | 5 | 1 | 0 | 0 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 8 | 3 | 4 | 3 | 3 | 1 | 13 | 1 | 0 | 25 | 0 | 1 | 0 | 2 | 0 |
19.1.4.3 | Protein homeostasis.protein quality control.plastidial Hsp70 chaperone system.nucleotide exchange factor (CGE) | 101 | 37 | 2 | 4 | 3 | 2 | 2 | 2 | 3 | 2 | 2 | 4 | 2 | 2 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 3 | 4 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 3 | 8 | 5 | 4 | 2 | 3 | 4 | 0 | 4 | 1 |
19.2.1.1.1.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Ac/N-degron pathway.Doa10 E3 ubiquitin ligase complex.E3 ubiquitin ligase component Doa10 | 100 | 35 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 0 | 2 | 3 | 6 | 2 | 0 | 1 | 0 | 1 | 2 | 2 | 1 | 3 | 2 | 1 | 5 | 2 | 1 | 2 | 1 | 2 | 2 | 4 | 16 | 16 | 2 | 2 | 2 | 0 | 2 | 1 |
19.2.3.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.SUMO deconjugation.protease (ELS) | 100 | 35 | 0 | 3 | 2 | 3 | 1 | 3 | 2 | 3 | 1 | 2 | 3 | 3 | 2 | 2 | 1 | 0 | 3 | 3 | 2 | 3 | 1 | 3 | 3 | 2 | 3 | 3 | 3 | 2 | 3 | 2 | 9 | 9 | 5 | 1 | 0 | 3 | 0 | 4 | 2 |
19.4.5.6.4 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M18-class aspartyl aminopeptidase (DAP) | 100 | 37 | 2 | 2 | 2 | 2 | 3 | 2 | 3 | 2 | 1 | 2 | 4 | 2 | 3 | 2 | 1 | 0 | 2 | 2 | 2 | 2 | 7 | 3 | 2 | 5 | 3 | 2 | 2 | 2 | 5 | 2 | 6 | 6 | 3 | 3 | 2 | 2 | 0 | 2 | 2 |
19.3.4.3 | Protein homeostasis.autophagy.autophagic cargo receptor activities.adapter protein (ATI1/2) | 98 | 33 | 3 | 2 | 2 | 2 | 1 | 4 | 4 | 2 | 0 | 3 | 1 | 3 | 5 | 0 | 1 | 0 | 3 | 2 | 1 | 2 | 4 | 4 | 2 | 0 | 2 | 3 | 3 | 2 | 0 | 2 | 8 | 6 | 4 | 1 | 3 | 6 | 0 | 6 | 1 |
19.2.6.2.2.10 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN11 | 97 | 37 | 2 | 3 | 1 | 1 | 2 | 2 | 4 | 2 | 1 | 3 | 3 | 3 | 2 | 1 | 2 | 0 | 2 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 2 | 1 | 2 | 1 | 4 | 1 | 4 | 8 | 5 | 1 | 4 | 5 | 0 | 4 | 1 |
19.1.3.2 | Protein homeostasis.protein quality control.mitochondrial Hsp70 chaperone system.co-chaperone (Hsp40) | 96 | 33 | 3 | 3 | 2 | 2 | 3 | 3 | 3 | 2 | 0 | 3 | 2 | 3 | 4 | 0 | 1 | 0 | 3 | 2 | 1 | 2 | 0 | 3 | 2 | 2 | 3 | 3 | 3 | 2 | 6 | 1 | 3 | 8 | 6 | 2 | 0 | 4 | 0 | 3 | 3 |
19.2.2.1.6.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).polyubiquitination.Ubc13-Uev1 conjugating E2 complex.component Ubc13 | 96 | 37 | 2 | 3 | 2 | 3 | 2 | 2 | 3 | 2 | 1 | 5 | 2 | 2 | 4 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 1 | 2 | 4 | 4 | 2 | 2 | 4 | 2 | 2 | 3 | 6 | 4 | 3 | 2 | 5 | 0 | 4 | 2 |
19.2.2.3.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB conjugation E2 protein (RCE1) | 96 | 37 | 2 | 2 | 1 | 2 | 1 | 3 | 2 | 3 | 1 | 2 | 2 | 2 | 3 | 1 | 1 | 0 | 3 | 3 | 3 | 2 | 3 | 2 | 2 | 5 | 4 | 2 | 2 | 4 | 5 | 1 | 8 | 6 | 4 | 3 | 1 | 2 | 0 | 2 | 1 |
19.3.3.5 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG12-ATG5 ATG8-PE-ligase E3 heterodimer | 95 | 37 | 3 | 3 | 1 | 3 | 2 | 3 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 0 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 3 | 2 | 2 | 3 | 4 | 2 | 8 | 9 | 3 | 2 | 4 | 2 | 0 | 2 | 2 |
19.2.6.2.1.4 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT4 | 94 | 37 | 2 | 2 | 1 | 2 | 1 | 4 | 3 | 2 | 1 | 3 | 2 | 3 | 3 | 1 | 1 | 0 | 1 | 2 | 2 | 2 | 2 | 3 | 1 | 3 | 4 | 2 | 2 | 2 | 2 | 2 | 7 | 9 | 6 | 2 | 3 | 2 | 0 | 1 | 3 |
19.5 | Protein homeostasis.protein repair | 93 | 37 | 2 | 2 | 2 | 2 | 1 | 2 | 4 | 2 | 5 | 5 | 2 | 2 | 4 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 3 | 2 | 8 | 2 | 2 | 2 | 1 | 4 | 2 | 5 | 6 | 3 | 1 | 2 | 1 | 0 | 2 | 1 |
19.5.1 | Protein homeostasis.protein repair.protein-L-isoaspartate methyltransferase | 93 | 37 | 2 | 2 | 2 | 2 | 1 | 2 | 4 | 2 | 5 | 5 | 2 | 2 | 4 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 3 | 2 | 8 | 2 | 2 | 2 | 1 | 4 | 2 | 5 | 6 | 3 | 1 | 2 | 1 | 0 | 2 | 1 |
19.3.4.2 | Protein homeostasis.autophagy.autophagic cargo receptor activities.adapter protein (NBR1) | 92 | 34 | 1 | 2 | 1 | 1 | 1 | 2 | 3 | 2 | 0 | 2 | 3 | 2 | 2 | 0 | 4 | 0 | 2 | 2 | 2 | 2 | 11 | 4 | 1 | 2 | 3 | 2 | 2 | 2 | 2 | 1 | 8 | 6 | 4 | 1 | 3 | 3 | 0 | 3 | 0 |
19.4.5.6.3 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M17-class leucyl aminopeptidase (LAP) | 92 | 37 | 3 | 2 | 2 | 3 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 0 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | 3 | 2 | 2 | 2 | 3 | 2 | 1 | 6 | 6 | 3 | 1 | 3 | 6 | 0 | 7 | 2 |
19.2.2.8.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.scaffold component CUL3 | 90 | 36 | 1 | 2 | 1 | 2 | 1 | 3 | 2 | 2 | 1 | 2 | 2 | 3 | 5 | 0 | 1 | 0 | 3 | 3 | 3 | 2 | 1 | 5 | 1 | 2 | 2 | 2 | 2 | 2 | 4 | 2 | 7 | 6 | 4 | 1 | 2 | 3 | 0 | 3 | 2 |
19.2.2.8.3.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.COP10-DET1 (CDD) subcomplex | 90 | 36 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 0 | 2 | 4 | 1 | 1 | 2 | 2 | 2 | 0 | 1 | 2 | 2 | 1 | 2 | 2 | 2 | 5 | 2 | 2 | 2 | 2 | 4 | 2 | 9 | 7 | 5 | 2 | 1 | 5 | 0 | 2 | 2 |
19.2.6.1.1.4 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-4 | 89 | 37 | 1 | 1 | 2 | 2 | 3 | 2 | 9 | 2 | 1 | 2 | 3 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 1 | 4 | 1 | 4 | 2 | 2 | 2 | 1 | 2 | 1 | 7 | 5 | 3 | 2 | 4 | 3 | 0 | 3 | 1 |
19.4.1.4 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C15-class pyrrolidone-carboxylate peptidase | 89 | 36 | 1 | 3 | 2 | 2 | 1 | 1 | 11 | 3 | 1 | 4 | 1 | 1 | 4 | 0 | 1 | 0 | 2 | 3 | 3 | 2 | 1 | 3 | 2 | 2 | 3 | 2 | 3 | 2 | 2 | 2 | 5 | 3 | 2 | 2 | 2 | 3 | 0 | 2 | 2 |
19.1.1.2.1.3 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.ERdj3B-BiP-SDF2 chaperone complex.component SDF2 | 87 | 37 | 2 | 2 | 2 | 1 | 1 | 2 | 5 | 2 | 1 | 4 | 1 | 3 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 3 | 2 | 2 | 2 | 1 | 4 | 1 | 10 | 6 | 3 | 2 | 3 | 2 | 0 | 2 | 1 |
19.2.2.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin maturation | 86 | 36 | 1 | 2 | 1 | 2 | 2 | 2 | 3 | 3 | 1 | 2 | 3 | 3 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 0 | 4 | 1 | 1 | 2 | 3 | 3 | 1 | 2 | 1 | 11 | 6 | 4 | 1 | 2 | 3 | 0 | 3 | 1 |
19.2.2.1.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin maturation.ubiquitin carboxyl-terminal hydrolase (UCH) | 86 | 36 | 1 | 2 | 1 | 2 | 2 | 2 | 3 | 3 | 1 | 2 | 3 | 3 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 0 | 4 | 1 | 1 | 2 | 3 | 3 | 1 | 2 | 1 | 11 | 6 | 4 | 1 | 2 | 3 | 0 | 3 | 1 |
19.2.2.3.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB maturation.ubiquitin carboxyl-terminal hydrolase (UCH1|2) | 86 | 36 | 1 | 2 | 1 | 2 | 2 | 2 | 3 | 3 | 1 | 2 | 3 | 3 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 0 | 4 | 1 | 1 | 2 | 3 | 3 | 1 | 2 | 1 | 11 | 6 | 4 | 1 | 2 | 3 | 0 | 3 | 1 |
19.2.6.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN2 | 86 | 37 | 1 | 1 | 2 | 2 | 1 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 3 | 4 | 1 | 4 | 2 | 2 | 2 | 2 | 2 | 2 | 9 | 6 | 4 | 2 | 3 | 4 | 0 | 4 | 1 |
19.2.6.2.3 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ubiquitin C-terminal hydrolase cofactor | 86 | 36 | 1 | 2 | 1 | 2 | 2 | 2 | 3 | 3 | 1 | 2 | 3 | 3 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 0 | 4 | 1 | 1 | 2 | 3 | 3 | 1 | 2 | 1 | 11 | 6 | 4 | 1 | 2 | 3 | 0 | 3 | 1 |
19.1.4.1 | Protein homeostasis.protein quality control.plastidial Hsp70 chaperone system.chaperone (cpHsc70) | 85 | 35 | 2 | 3 | 2 | 2 | 1 | 2 | 3 | 1 | 1 | 3 | 2 | 2 | 3 | 1 | 2 | 0 | 2 | 2 | 2 | 0 | 1 | 3 | 1 | 5 | 2 | 2 | 2 | 2 | 4 | 2 | 6 | 6 | 4 | 2 | 0 | 3 | 0 | 3 | 1 |
19.2.2.3.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB maturation.ubiquitin carboxyl-terminal hydrolase (UCH3) | 85 | 35 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 3 | 1 | 4 | 2 | 2 | 1 | 1 | 1 | 0 | 3 | 3 | 3 | 2 | 0 | 3 | 1 | 1 | 1 | 3 | 3 | 2 | 2 | 0 | 8 | 9 | 6 | 1 | 1 | 2 | 0 | 4 | 2 |
19.2.2.1.5.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.U-Box E3 ligase activities.bifunctional co-chaperone and E3 ubiquitin ligase (CHIP) | 83 | 37 | 1 | 2 | 1 | 1 | 2 | 2 | 3 | 2 | 1 | 2 | 3 | 2 | 2 | 1 | 2 | 0 | 2 | 2 | 2 | 3 | 5 | 1 | 3 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 6 | 6 | 4 | 4 | 1 | 2 | 0 | 2 | 2 |
19.2.6.1.2.3 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-3 | 82 | 37 | 2 | 2 | 2 | 2 | 1 | 2 | 5 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 3 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 8 | 6 | 3 | 1 | 3 | 4 | 0 | 3 | 1 |
19.4.5.8.1.2.1 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH mitochondrial protease complexes.FtsH3/10 matrix-AAA protease heterodimers.component Fts3|10 | 82 | 36 | 3 | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 3 | 1 | 2 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 3 | 0 | 3 | 1 | 3 | 2 | 2 | 2 | 3 | 4 | 1 | 10 | 6 | 4 | 1 | 2 | 1 | 0 | 1 | 2 |
19.2.2.3.5.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB ligase E3 activities.RUB ligase E3 protein (RBX1) | 81 | 37 | 1 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 1 | 2 | 1 | 2 | 4 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 4 | 1 | 1 | 3 | 3 | 2 | 2 | 2 | 2 | 2 | 6 | 6 | 2 | 2 | 2 | 3 | 0 | 2 | 2 |
19.2.2.8.1.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.UBQ-E2-recruiting component RBX1 | 81 | 37 | 1 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 1 | 2 | 1 | 2 | 4 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 4 | 1 | 1 | 3 | 3 | 2 | 2 | 2 | 2 | 2 | 6 | 6 | 2 | 2 | 2 | 3 | 0 | 2 | 2 |
19.2.6.2.1.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT1 | 81 | 37 | 5 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 3 | 2 | 2 | 3 | 1 | 1 | 0 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 4 | 2 | 2 | 2 | 2 | 2 | 6 | 6 | 2 | 2 | 2 | 1 | 0 | 1 | 2 |
19.2.6.2.2.5 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN6 | 81 | 35 | 1 | 2 | 1 | 1 | 1 | 2 | 4 | 2 | 1 | 3 | 3 | 3 | 2 | 1 | 1 | 0 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 2 | 4 | 2 | 2 | 1 | 2 | 1 | 7 | 8 | 3 | 0 | 0 | 3 | 0 | 4 | 1 |
19.2.2.8.3.4.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.COP1-SPA substrate adaptor subcomplex.regulator component SPA | 80 | 33 | 3 | 1 | 2 | 3 | 2 | 2 | 1 | 0 | 0 | 4 | 1 | 1 | 5 | 0 | 1 | 0 | 2 | 1 | 2 | 1 | 2 | 1 | 4 | 2 | 4 | 2 | 2 | 4 | 2 | 2 | 4 | 3 | 4 | 2 | 0 | 3 | 0 | 4 | 3 |
19.2.5 | Protein homeostasis.ubiquitin-proteasome system.chloroplast-associated protein degradation (CHLORAD) | 80 | 34 | 2 | 2 | 3 | 3 | 2 | 2 | 2 | 1 | 0 | 2 | 2 | 2 | 3 | 0 | 1 | 0 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 2 | 2 | 5 | 6 | 4 | 2 | 0 | 2 | 0 | 3 | 2 |
19.2.6.2.2.6 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN7 | 80 | 36 | 1 | 0 | 1 | 1 | 2 | 2 | 6 | 2 | 1 | 1 | 3 | 2 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 3 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 9 | 6 | 3 | 1 | 3 | 2 | 0 | 2 | 1 |
19.1.1.1.1.1 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system.CNX-CRT cycle.lectin chaperone (CNX) | 79 | 36 | 1 | 2 | 2 | 2 | 1 | 2 | 3 | 1 | 1 | 3 | 2 | 2 | 4 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 3 | 2 | 5 | 3 | 1 | 1 | 2 | 6 | 0 | 3 | 6 | 4 | 1 | 1 | 2 | 0 | 2 | 2 |
19.2.6.1.2.6 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-6 | 79 | 37 | 1 | 2 | 1 | 1 | 1 | 2 | 3 | 3 | 1 | 2 | 1 | 2 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 3 | 1 | 2 | 2 | 2 | 2 | 1 | 4 | 1 | 8 | 3 | 2 | 2 | 2 | 4 | 0 | 5 | 1 |
19.2.3.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.SUMO deconjugation.protease (OTS) | 78 | 31 | 2 | 2 | 1 | 2 | 1 | 3 | 2 | 1 | 0 | 4 | 3 | 2 | 2 | 0 | 1 | 0 | 3 | 2 | 3 | 0 | 0 | 1 | 2 | 5 | 1 | 6 | 3 | 2 | 3 | 1 | 0 | 9 | 6 | 1 | 0 | 1 | 0 | 1 | 2 |
19.2.6.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN1 | 78 | 36 | 1 | 1 | 1 | 2 | 2 | 2 | 6 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 0 | 2 | 3 | 3 | 2 | 1 | 2 | 2 | 2 | 3 | 1 | 3 | 2 | 2 | 1 | 3 | 9 | 5 | 1 | 0 | 2 | 0 | 2 | 1 |
19.2.6.1.1.7 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-7 | 77 | 36 | 1 | 1 | 2 | 1 | 1 | 1 | 4 | 1 | 1 | 2 | 3 | 1 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 3 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 8 | 6 | 4 | 1 | 0 | 4 | 0 | 4 | 2 |
19.2.6.2.2.3 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN3 | 77 | 37 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 3 | 2 | 2 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 4 | 1 | 4 | 4 | 1 | 2 | 2 | 2 | 1 | 4 | 6 | 1 | 2 | 3 | 2 | 0 | 2 | 1 |
19.2.6.2.1.6 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT6 | 76 | 37 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 1 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 1 | 8 | 6 | 3 | 2 | 1 | 1 | 0 | 2 | 2 |
19.2.6.2.2.8 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN9 | 76 | 37 | 1 | 1 | 1 | 2 | 1 | 2 | 4 | 2 | 1 | 2 | 3 | 3 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 1 | 4 | 4 | 3 | 2 | 2 | 2 | 0 | 3 | 1 |
19.1.1.1.4 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system.alpha-1,2 exomannosidase (MNL) | 75 | 35 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 2 | 0 | 2 | 2 | 1 | 2 | 0 | 2 | 2 | 1 | 3 | 2 | 2 | 2 | 5 | 1 | 5 | 6 | 4 | 2 | 0 | 1 | 0 | 2 | 2 |
19.2.2.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.HUB conjugation | 74 | 34 | 2 | 2 | 1 | 2 | 1 | 2 | 3 | 3 | 1 | 1 | 2 | 1 | 3 | 1 | 2 | 0 | 3 | 3 | 2 | 2 | 1 | 3 | 1 | 1 | 3 | 3 | 3 | 0 | 2 | 1 | 6 | 6 | 2 | 0 | 2 | 1 | 0 | 0 | 2 |
19.2.2.4.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.HUB conjugation.ubiquitin-fold protein (HUB) | 74 | 34 | 2 | 2 | 1 | 2 | 1 | 2 | 3 | 3 | 1 | 1 | 2 | 1 | 3 | 1 | 2 | 0 | 3 | 3 | 2 | 2 | 1 | 3 | 1 | 1 | 3 | 3 | 3 | 0 | 2 | 1 | 6 | 6 | 2 | 0 | 2 | 1 | 0 | 0 | 2 |
19.2.6.2.2.11 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN12 | 74 | 36 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 2 | 1 | 2 | 1 | 2 | 1 | 4 | 10 | 8 | 1 | 2 | 3 | 0 | 3 | 1 |
19.1.5.4 | Protein homeostasis.protein quality control.cytosolic Hsp70 chaperone system.nucleotide exchange factor (FES1) | 73 | 35 | 3 | 1 | 1 | 3 | 1 | 2 | 3 | 2 | 0 | 2 | 2 | 2 | 1 | 0 | 1 | 0 | 2 | 2 | 2 | 2 | 1 | 4 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 5 | 6 | 3 | 1 | 1 | 3 | 0 | 3 | 2 |
19.2.1.3.1.2 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex.catalytic component GID2 | 73 | 36 | 2 | 2 | 1 | 3 | 1 | 2 | 2 | 1 | 1 | 2 | 3 | 4 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 4 | 1 | 4 | 4 | 1 | 1 | 1 | 2 | 1 | 3 | 9 | 5 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.2.1.5.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RING-domain E3 ligase activities.RING-C2-class E3 ligase | 73 | 35 | 2 | 2 | 2 | 3 | 2 | 2 | 3 | 1 | 0 | 2 | 1 | 2 | 6 | 0 | 3 | 0 | 2 | 2 | 1 | 1 | 2 | 4 | 1 | 4 | 2 | 1 | 1 | 2 | 2 | 1 | 3 | 3 | 2 | 2 | 2 | 1 | 0 | 1 | 2 |
19.2.6.1.1.5 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-5 | 73 | 36 | 1 | 2 | 2 | 2 | 1 | 2 | 3 | 2 | 1 | 2 | 2 | 2 | 3 | 1 | 2 | 0 | 1 | 1 | 1 | 0 | 2 | 2 | 2 | 3 | 2 | 2 | 1 | 2 | 2 | 1 | 8 | 6 | 4 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.6.2.2.9 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN10 | 73 | 36 | 1 | 2 | 1 | 1 | 1 | 1 | 4 | 3 | 1 | 3 | 1 | 1 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 3 | 0 | 2 | 1 | 3 | 2 | 2 | 1 | 2 | 2 | 8 | 3 | 2 | 1 | 2 | 3 | 0 | 3 | 1 |
19.2.6.2.1.3 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT3 | 72 | 36 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 3 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 4 | 2 | 1 | 2 | 2 | 7 | 2 | 6 | 6 | 4 | 1 | 1 | 1 | 0 | 1 | 3 |
19.4.1.6 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C50-class protease separase (AESP) | 72 | 35 | 1 | 3 | 1 | 1 | 2 | 1 | 4 | 1 | 1 | 2 | 1 | 3 | 2 | 0 | 1 | 0 | 1 | 3 | 3 | 1 | 2 | 3 | 2 | 1 | 1 | 2 | 3 | 1 | 1 | 1 | 7 | 3 | 4 | 6 | 0 | 1 | 0 | 1 | 1 |
19.4.5.8.1.2.2 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH mitochondrial protease complexes.FtsH3/10 matrix-AAA protease heterodimers.component prohibitin | 72 | 34 | 2 | 0 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 1 | 2 | 2 | 2 | 2 | 3 | 1 | 2 | 2 | 2 | 2 | 3 | 2 | 1 | 3 | 8 | 5 | 0 | 4 | 2 | 0 | 0 | 1 |
19.2.2.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO activating E1 heterodimer.large component SAE2 | 71 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 12 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 6 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 3 |
19.2.6.1.2.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-1 | 70 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 1 | 2 | 1 | 3 | 6 | 5 | 2 | 3 | 2 | 0 | 2 | 1 |
19.4.2.1.3 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT3) | 70 | 24 | 2 | 0 | 0 | 15 | 3 | 2 | 4 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 2 | 0 | 0 | 5 | 2 | 2 | 1 | 0 | 1 | 2 | 6 | 2 | 7 | 0 | 2 | 0 | 2 | 1 |
19.2.4.1.1 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).HRD1 E3 ubiquitin ligase complex.E3 ubiquitin ligase component HRD1 | 69 | 37 | 1 | 3 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 8 | 8 | 3 | 1 | 1 | 3 | 0 | 2 | 1 |
19.2.6.2.1.5 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT5 | 69 | 36 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 0 | 2 | 2 | 2 | 2 | 0 | 3 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 4 | 5 | 3 | 2 | 4 | 1 | 0 | 2 | 2 |
19.1.3.3 | Protein homeostasis.protein quality control.mitochondrial Hsp70 chaperone system.nucleotide exchange factor (MGE) | 67 | 37 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 0 | 2 | 2 | 2 | 1 | 1 | 3 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.2.3.3.1.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN1 | 67 | 37 | 1 | 2 | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 2 | 4 | 2 | 3 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 4 | 8 | 4 | 1 | 2 | 1 | 0 | 1 | 2 |
19.2.6.1.1.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-2 | 67 | 35 | 1 | 2 | 1 | 2 | 0 | 1 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 0 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 4 | 6 | 4 | 1 | 2 | 3 | 0 | 2 | 1 |
19.2.6.1.2.5 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-5 | 67 | 37 | 2 | 2 | 1 | 2 | 1 | 1 | 3 | 1 | 1 | 3 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 3 | 2 | 3 | 2 | 2 | 1 | 1 | 2 | 2 | 1 | 5 | 3 | 1 | 1 | 2 | 1 | 0 | 1 | 6 |
19.2.6.2.1.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.ATPase components.regulatory component RPT2 | 67 | 36 | 1 | 2 | 0 | 2 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 3 | 2 | 1 | 2 | 1 | 2 | 1 | 5 | 6 | 4 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.6.2.2.4 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN5 | 67 | 36 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 3 | 2 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 2 | 0 | 1 | 2 | 3 | 2 | 1 | 2 | 2 | 1 | 8 | 3 | 1 | 1 | 1 | 4 | 0 | 3 | 1 |
19.3.3.2 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG8-maturation peptidase (ATG4) | 67 | 37 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 2 | 2 | 1 | 4 | 3 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 1 | 4 | 0 | 6 | 3 |
19.4.5.6.2 | Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M24-class methionyl aminopeptidase (MAP2) | 67 | 35 | 1 | 3 | 1 | 2 | 1 | 1 | 0 | 2 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 0 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 3 | 1 | 4 | 0 | 8 | 5 | 3 | 1 | 2 | 1 | 0 | 1 | 1 |
19.1.6.3 | Protein homeostasis.protein quality control.Hsp90 chaperone system.Hsp90-co-chaperone (SGT1) | 66 | 36 | 2 | 1 | 1 | 2 | 1 | 1 | 4 | 2 | 1 | 4 | 1 | 1 | 3 | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 2 | 2 | 1 | 1 | 3 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 1 | 2 | 2 | 2 | 0 | 2 | 1 |
19.2.3.2.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.SUMO deconjugation.peptidase (DeSI) | 66 | 37 | 2 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 3 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 5 | 5 | 2 | 1 | 2 | 2 | 0 | 1 | 1 |
19.2.2.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).ubiquitin-fold protein (RUB) | 65 | 27 | 0 | 0 | 2 | 2 | 0 | 2 | 0 | 0 | 1 | 1 | 7 | 2 | 2 | 0 | 0 | 0 | 2 | 3 | 2 | 1 | 2 | 0 | 1 | 1 | 3 | 2 | 2 | 1 | 0 | 1 | 1 | 14 | 5 | 1 | 0 | 2 | 0 | 1 | 1 |
19.2.6.1.1.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-1 | 65 | 37 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 4 | 3 | 2 | 1 | 1 | 1 | 1 | 3 | 4 | 3 | 1 | 1 | 2 | 0 | 3 | 1 |
19.2.6.1.2.2 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-2 | 65 | 36 | 2 | 0 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 3 | 1 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 7 | 1 | 2 | 1 | 1 | 2 | 0 | 2 | 1 |
19.3.2.1.2 | Protein homeostasis.autophagy.ATG9-2-18 membrane shuttling complex.components.component ATG2 | 65 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 0 | 2 | 2 | 2 | 3 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 6 | 6 | 5 | 1 | 1 | 2 | 0 | 2 | 2 |
19.2.1.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.Arg/N-recognin activities.type-I-residues E3 ubiquitin ligase (PRT6) | 63 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 10 | 1 | 1 | 1 | 2 | 2 | 1 | 3 | 6 | 4 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.1.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.Arg/N-recognin activities.type-II-residues E3 ubiquitin ligase (PRT1) | 63 | 36 | 1 | 4 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 3 | 1 | 2 | 2 | 1 | 0 | 0 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 5 | 3 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 3 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.2.3.3.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB activating E1 heterodimer.small component AXR1/AXL | 63 | 37 | 1 | 1 | 1 | 2 | 1 | 1 | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 1 | 4 | 6 | 4 | 1 | 1 | 2 | 0 | 2 | 1 |
19.4.2.9.5 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.chaperone component ClpD | 63 | 33 | 2 | 1 | 2 | 1 | 1 | 2 | 0 | 2 | 0 | 1 | 2 | 2 | 2 | 1 | 1 | 0 | 2 | 1 | 2 | 0 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 0 | 1 | 7 | 6 | 3 | 1 | 1 | 2 | 0 | 2 | 1 |
19.1.1.2.1.2 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.ERdj3B-BiP-SDF2 chaperone complex.co-chaperone component ERdj3a | 62 | 36 | 1 | 2 | 1 | 1 | 1 | 1 | 4 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 7 | 3 | 2 | 1 | 2 | 3 | 0 | 3 | 1 |
19.2.2.8.1.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.adaptor protein exchange factor (CAND1) | 62 | 36 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 4 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 8 | 5 | 1 | 0 | 1 | 0 | 1 | 2 |
19.2.3.1.1.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP14) | 62 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 3 | 0 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 4 | 4 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 5 | 3 | 2 | 5 | 2 | 1 | 0 | 1 | 1 |
19.3.2.1.1 | Protein homeostasis.autophagy.ATG9-2-18 membrane shuttling complex.components.component ATG9 | 62 | 35 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 2 | 1 | 0 | 3 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 8 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.3.3.4 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG8-conjugation E2 protein (ATG3) | 62 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 3 | 2 | 1 | 1 | 2 | 1 | 7 | 3 | 2 | 1 | 2 | 5 | 0 | 2 | 1 |
19.2.1.3.1.5 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex.component GID8 | 61 | 34 | 1 | 2 | 1 | 3 | 1 | 1 | 3 | 1 | 1 | 2 | 2 | 3 | 3 | 0 | 2 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 2 | 1 | 1 | 2 | 2 | 1 | 0 | 6 | 4 | 2 | 0 | 1 | 0 | 2 | 1 |
19.2.3.1.1.9 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP23) | 61 | 34 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 0 | 2 | 1 | 2 | 3 | 0 | 1 | 0 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 5 | 6 | 3 | 2 | 1 | 0 | 0 | 1 | 1 |
19.2.6.1.2.7 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-7 | 61 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 5 | 4 | 1 | 2 | 2 | 0 | 2 | 3 |
19.2.1.3.1.1 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex.component GID1 | 60 | 36 | 1 | 1 | 1 | 5 | 1 | 1 | 3 | 1 | 2 | 3 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 3 | 2 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.2.2.8.3.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.core adaptor component DDB1 | 60 | 37 | 1 | 1 | 1 | 2 | 1 | 3 | 2 | 1 | 1 | 2 | 2 | 4 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 5 | 3 | 1 | 1 | 2 | 0 | 2 | 1 |
19.2.4.1.4 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).HRD1 E3 ubiquitin ligase complex.substrate recruitment component OS9 | 60 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 5 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 4 | 1 | 1 | 1 | 2 | 1 | 5 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.4.2.1.7 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT6.2) | 60 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | 1 | 1 | 3 | 4 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 2 | 0 | 2 | 2 | 1 | 1 | 3 | 2 | 1 | 2 | 3 | 2 | 1 | 1 | 3 | 0 | 3 | 2 |
19.1.2.3 | Protein homeostasis.protein quality control.ribosome-associated chaperone activities.co-chaperone (ZRF) | 59 | 36 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 2 | 2 | 1 | 1 | 2 | 1 | 6 | 3 | 2 | 1 | 0 | 4 | 0 | 5 | 2 |
19.2.2.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO activating E1 heterodimer.small component SAE1 | 59 | 36 | 2 | 3 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 0 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 3 | 6 | 4 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.6.2.2.7 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN8 | 59 | 37 | 1 | 2 | 2 | 2 | 1 | 1 | 3 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 2 | 2 | 2 | 0 | 2 | 1 |
19.3.1.3 | Protein homeostasis.autophagy.ATG1-13 autophagosome assembly control complex.multifunctional scaffold component ATG11 | 59 | 36 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 4 | 1 | 6 | 3 | 2 | 1 | 1 | 4 | 0 | 5 | 1 |
19.4.5.5.1 | Protein homeostasis.proteolysis.metallopeptidase activities.M48 families.zinc metalloprotease (PGM48) | 59 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 10 | 0 | 10 | 1 |
19.2.2.8.3.3.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.COP10-DET1 (CDD) subcomplex.regulator component DET1 | 58 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 3 | 1 | 1 | 1 | 1 | 2 | 1 | 6 | 4 | 3 | 1 | 1 | 4 | 0 | 2 | 1 |
19.2.3.1.1.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP6-7) | 58 | 37 | 1 | 1 | 1 | 2 | 1 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 1 | 1 | 1 | 3 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 5 | 2 | 1 | 2 | 2 | 0 | 3 | 1 |
19.2.3.3.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN2 | 58 | 37 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 2 | 1 | 1 | 3 | 2 | 1 | 4 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.2.4.1.3 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).HRD1 E3 ubiquitin ligase complex.adaptor protein component HRD3 | 58 | 36 | 2 | 3 | 1 | 2 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 3 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 2 | 2 | 0 | 3 | 1 |
19.2.4.2.2.2 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction.NPL4-UFD1 CDC48-cofactor heterodimer.component NPL4 | 58 | 36 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 3 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 0 | 3 | 2 | 1 | 2 | 4 | 0 | 6 | 1 |
19.2.2.1.5.4.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-ligase E3 activities.RBR-type E3 ligase activities.E3 ubiquitin ligase (RBR-Helicase) | 57 | 30 | 2 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 0 | 2 | 2 | 2 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 2 | 0 | 2 | 1 | 0 | 2 | 1 | 1 | 2 | 0 | 1 | 4 | 9 | 6 | 1 | 0 | 1 | 0 | 1 | 1 |
19.2.3.1.1.8 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP22) | 57 | 36 | 2 | 2 | 1 | 1 | 1 | 1 | 3 | 1 | 0 | 5 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 1 | 1 | 2 | 2 | 2 | 5 | 3 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.3.3.1.7 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN7 | 57 | 36 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 1 | 2 | 2 | 4 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 2 | 1 | 3 | 0 | 3 | 1 |
19.2.6.1.1.3 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-3 | 57 | 36 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 1 | 3 | 2 | 1 | 1 | 3 | 1 | 3 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 0 | 1 | 2 | 0 | 2 | 1 |
19.4.5.7.2 | Protein homeostasis.proteolysis.metallopeptidase activities.carboxypeptidase activities.M14-class carboxypeptidase (SOL) | 57 | 36 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 4 | 3 | 1 | 3 | 2 | 1 | 1 | 1 | 2 | 1 | 5 | 3 | 1 | 1 | 1 | 3 | 0 | 3 | 1 |
19.1.8.12 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-ER protein | 56 | 28 | 3 | 2 | 2 | 1 | 0 | 2 | 1 | 1 | 0 | 3 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 1 | 2 | 0 | 0 | 1 | 2 | 2 | 3 | 0 | 1 | 2 | 5 | 3 | 1 | 2 | 3 | 0 | 3 | 0 |
19.2.2.3.5.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB ligase E3 activities.RUB ligase E3 protein (DCN1) | 56 | 33 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 0 | 3 | 1 | 3 | 1 | 2 | 2 | 2 | 4 | 2 | 4 | 3 | 2 | 1 | 0 | 0 | 0 | 1 | 1 |
19.1.2.2 | Protein homeostasis.protein quality control.ribosome-associated chaperone activities.co-chaperone (Jjj1) | 55 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 2 | 1 | 1 | 0 | 1 | 1 | 2 | 4 | 1 | 4 | 3 | 2 | 0 | 1 | 4 | 0 | 4 | 1 |
19.2.1.3.1.3 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex.N-recognin component GID4 | 55 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 0 | 2 | 0 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 4 | 3 | 2 | 1 | 0 | 4 | 0 | 4 | 2 |
19.2.4.3.1 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate processing.E4 multiubiquitination enzyme (UFD2) | 55 | 35 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 3 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 4 | 2 | 1 | 1 | 3 | 1 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 1 | 1 | 3 | 0 | 2 | 1 |
19.2.6.3 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.regulation | 55 | 37 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 6 | 5 | 3 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.6.3.1 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.regulation.regulatory protein (PTRE1) | 55 | 37 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 6 | 5 | 3 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.6.1.1.6 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.alpha-type components.component alpha type-6 | 54 | 37 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 3 | 3 | 2 | 1 | 3 | 1 | 0 | 2 | 1 |
19.2.6.1.2.4 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.20S core particle.beta-type components.component beta type-4 | 54 | 36 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 3 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 1 | 1 | 2 | 2 | 0 | 2 | 2 |
19.4.2.9.3 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.plant-specific stabilizing component ClpT | 54 | 35 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 3 | 1 | 1 | 2 | 2 | 1 | 6 | 3 | 2 | 1 | 1 | 2 | 0 | 2 | 1 |
19.4.5.5.2 | Protein homeostasis.proteolysis.metallopeptidase activities.M48 families.zinc metalloprotease (STE24) | 54 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 2 | 0 | 2 | 0 | 1 | 1 | 1 | 1 | 4 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 0 | 3 | 0 | 2 | 1 |
19.1.1.2.3 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.co-chaperone (P58/ERdj6) | 53 | 37 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 2 | 4 | 1 | 1 | 1 | 1 | 0 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.2.8.3.4.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.COP1-SPA substrate adaptor subcomplex.component COP1 | 53 | 33 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 9 | 3 | 1 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 2 | 0 | 1 | 0 | 2 | 2 |
19.3.3.5.2 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG12-ATG5 ATG8-PE-ligase E3 heterodimer.component ATG5 | 53 | 36 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 5 | 5 | 2 | 1 | 2 | 1 | 0 | 1 | 1 |
19.1.1.2.6 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.nucleotide exchange factor (Sil1) | 52 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 3 | 1 | 3 | 2 | 3 | 2 | 1 | 2 | 3 | 2 | 3 | 1 | 1 | 1 | 2 | 0 | 2 | 1 |
19.2.3.2.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.SUMO deconjugation.protease (FUG) | 52 | 28 | 0 | 1 | 0 | 1 | 1 | 3 | 1 | 1 | 0 | 2 | 2 | 4 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 3 | 1 | 0 | 3 | 2 | 1 | 1 | 2 | 0 | 1 | 4 | 7 | 3 | 1 | 0 | 1 | 0 | 0 | 1 |
19.2.3.3.1.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN5 | 52 | 36 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 6 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 0 | 2 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.4.1.5 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).HRD1 E3 ubiquitin ligase complex.associated plant-specific component EBS7 | 52 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 1 | 1 | 4 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 0 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.2.6.2.2.12 | Protein homeostasis.ubiquitin-proteasome system.26S proteasome.19S regulatory particle.non-ATPase components.regulatory component RPN13 | 52 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 4 | 2 | 1 | 1 | 1 | 4 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.2.2.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO chain-forming-ligase E4 enzyme (PIAL) | 51 | 34 | 1 | 2 | 1 | 2 | 1 | 1 | 3 | 1 | 0 | 2 | 0 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 3 | 3 | 2 | 3 | 1 | 1 | 0 | 1 | 2 |
19.2.3.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.SUMO deconjugation.protease (SPF) | 51 | 31 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 0 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 8 | 4 | 1 | 1 | 2 | 2 | 1 | 1 | 3 | 2 | 1 | 0 | 1 | 0 | 0 | 2 |
19.2.3.3.1.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN3 | 51 | 36 | 3 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 1 | 2 | 0 | 2 | 1 |
19.2.4.3.2 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate processing.ubiquitin-binding adaptor (UFD3) | 51 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 4 | 3 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.4.4.2 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).delivery to proteasome.proteasome adaptor protein (DDI1) | 51 | 35 | 1 | 2 | 2 | 1 | 1 | 1 | 3 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 5 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.3.4.1 | Protein homeostasis.autophagy.autophagic cargo receptor activities.adapter protein (TSPO) | 51 | 31 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 2 | 2 | 1 | 0 | 1 | 1 | 2 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 5 | 3 | 1 | 1 | 1 | 6 | 1 | 2 | 3 | 2 | 0 | 0 | 2 | 0 | 1 | 1 |
19.4.5.2 | Protein homeostasis.proteolysis.metallopeptidase activities.M8-class metalloprotease (Leishmanolysin) | 51 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 4 | 2 | 1 | 1 | 1 | 2 | 2 | 3 | 3 | 2 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.1.3.1.4 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex.component GID5 | 50 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 4 | 3 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.2.2.6.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.UFM conjugation.ubiquitin-fold protein (UFM) | 50 | 34 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 0 | 1 | 4 | 1 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 1 | 3 | 3 | 0 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.2.8.2.2.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.BTB/POZ substrate adaptor components.component BPH1 | 50 | 27 | 3 | 0 | 1 | 2 | 1 | 0 | 2 | 1 | 0 | 3 | 1 | 1 | 3 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 3 | 0 | 2 | 1 | 1 | 1 | 0 | 1 | 5 | 5 | 4 | 1 | 0 | 1 | 0 | 0 | 1 |
19.3.1.4 | Protein homeostasis.autophagy.ATG1-13 autophagosome assembly control complex.accessory component ATG101 | 50 | 35 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 3 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 0 | 1 | 2 | 2 | 2 | 1 | 0 | 2 | 0 | 2 | 1 |
19.4.2.9.6 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.adaptor component ClpS | 50 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 2 | 2 | 2 | 0 | 2 | 1 |
19.1.1.2.2 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.co-chaperone (ERdj3a) | 49 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 6 | 3 | 0 | 1 | 1 | 3 | 0 | 3 | 0 |
19.1.1.2.5 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.nucleotide exchange factor (Grp170) | 49 | 34 | 1 | 2 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 2 | 0 | 2 | 0 | 2 | 1 |
19.2.1.1.1.2 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Ac/N-degron pathway.Doa10 E3 ubiquitin ligase complex.E2 ubiquitin-conjugating component Ubc32 | 49 | 35 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 5 | 3 | 2 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.1.2.1.2 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.N-terminal modification.arginyl-tRNA-protein transferase (ATE) | 49 | 36 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 3 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 2 |
19.2.3.1.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.deubiquitinase (OTU1) | 49 | 35 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.2.3.3.1.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN4 | 49 | 36 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 3 | 0 | 1 | 0 | 1 | 1 |
19.2.4.2.3 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate extraction.associated factor (PUX1) | 49 | 34 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 0 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 4 | 2 | 3 | 3 | 2 | 1 | 2 | 2 | 0 | 1 | 1 |
19.2.2.6.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.UFM conjugation.UFM-ligase E3 protein | 48 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 6 | 3 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.3.1.2.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.deubiquitinase (OTU2) | 48 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.3.1.2.5 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.histone deubiquinating protease (OTLD1) | 48 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 1 | 3 | 3 | 1 | 1 | 1 | 2 | 0 | 2 | 1 |
19.2.1.3.1.6 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Pro/N-degron pathway.ubiquitin protein ligase complex.component GID9 | 47 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 4 | 1 | 2 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.2.2.4.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.SUMO conjugation (sumoylation).SUMO E3 ligase activities.E3 ligase (HPY2) | 47 | 34 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 2 | 1 | 1 | 1 | 2 | 0 | 0 | 4 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.2.3.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB maturation.deneddylase (DEN1) | 47 | 33 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 3 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 3 | 5 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.3.1.1.10 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP24) | 47 | 34 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 3 | 3 | 2 | 1 | 0 | 2 | 0 | 2 | 1 |
19.2.3.1.2.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.deubiquitinase (OTU5) | 47 | 35 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 0 | 1 | 0 | 0 | 1 | 1 |
19.1.8.8 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-M-I protein | 46 | 28 | 1 | 0 | 1 | 2 | 0 | 1 | 2 | 1 | 0 | 3 | 1 | 2 | 1 | 0 | 0 | 0 | 1 | 2 | 2 | 0 | 4 | 1 | 1 | 0 | 3 | 1 | 1 | 1 | 0 | 1 | 3 | 3 | 1 | 3 | 1 | 1 | 0 | 1 | 0 |
19.2.1.1.1.3 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Ac/N-degron pathway.Doa10 E3 ubiquitin ligase complex.E2 ubiquitin-conjugating component Ubc33/34 | 46 | 35 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 0 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 3 | 2 | 1 | 0 | 2 | 0 | 2 | 1 |
19.2.2.6.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.UFM conjugation.UFM-activating E1 protein | 46 | 33 | 2 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 0 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 5 | 3 | 1 | 1 | 2 | 1 | 0 | 1 | 1 |
19.2.2.6.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.UFM conjugation.UFM-conjugation E2 protein | 46 | 34 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 2 | 1 | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 3 | 2 | 1 | 2 | 1 | 0 | 2 | 1 |
19.2.3.3.1.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN6 | 46 | 34 | 1 | 0 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 4 | 2 | 2 | 1 | 1 | 2 | 0 | 2 | 1 |
19.2.3.3.1.8 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.RUB deconjugation of neddylated cullin.COP9 signalosome complex.component CSN8 | 46 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 0 | 1 | 3 | 2 | 2 | 1 | 2 | 2 | 0 | 1 | 1 |
19.4.5.7.1 | Protein homeostasis.proteolysis.metallopeptidase activities.carboxypeptidase activities.M14-class carboxypeptidase | 46 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.4.5.8.2.2 | Protein homeostasis.proteolysis.metallopeptidase activities.FtsH endopeptidase activities.FtsH plastidial protease complexes.component FtsH7|9 | 46 | 35 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 1 | 2 | 0 | 2 | 1 |
19.1.1.1.3 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system.alpha-1,2 mannosidase (MNS) | 45 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.3.1.1.12 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP26) | 45 | 32 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 0 | 2 | 1 | 0 | 1 | 0 | 1 | 2 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 2 | 0 | 3 | 2 | 1 | 0 | 2 | 0 | 2 | 1 |
19.2.5.1 | Protein homeostasis.ubiquitin-proteasome system.chloroplast-associated protein degradation (CHLORAD).ubiquitin protein ligase (SP1) | 45 | 34 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 0 | 1 | 0 | 2 | 2 |
19.3.2.2 | Protein homeostasis.autophagy.ATG9-2-18 membrane shuttling complex.ATG9-transport factor (ATG27) | 45 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 4 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.3.3.3 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG8/12-activating E1 protein (ATG7) | 45 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 4 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.4.2.5 | Protein homeostasis.proteolysis.serine-type peptidase activities.S49-class plastidial protease (SppA) | 45 | 34 | 1 | 1 | 0 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 0 | 2 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 2 | 1 | 1 | 0 | 1 | 1 |
19.1.1.1.2 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.calnexin/calreticulin chaperone system.UDP-glucose glycoprotein glucosyltransferase (UGGT) | 44 | 34 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.2.2.3.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.RUB/NEDD8 conjugation (neddylation).RUB activating E1 heterodimer.large component ECR1 | 44 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 2 | 1 | 1 | 1 | 0 | 0 | 1 |
19.2.2.7 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.URM conjugation | 44 | 34 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 0 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 4 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.2.7.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.URM conjugation.ubiquitin-fold protein (URM) | 44 | 34 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 0 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 4 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.4.3.4 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate processing.deglycosylating peptide:N-glycanase (PNG1) | 44 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 5 | 1 | 1 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 2 |
19.4.1.2 | Protein homeostasis.proteolysis.cysteine-type peptidase activities.C2-class calcium-activated protease (Phytocalpain) | 44 | 33 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 0 | 1 | 1 | 0 | 2 | 0 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.1.1.2.4 | Protein homeostasis.protein quality control.ER Quality Control (ERQC) machinery.BiP chaperone system.co-chaperone (ERdj7) | 43 | 35 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 3 | 3 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
19.1.8.6 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-VI protein | 43 | 30 | 2 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 2 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 1 | 0 | 1 | 4 | 3 | 2 | 1 | 2 | 2 | 0 | 2 | 1 |
19.2.2.8.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.scaffold component CUL4 | 43 | 32 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 3 | 2 | 1 | 1 | 2 | 2 | 1 | 1 | 3 | 2 | 1 | 0 | 2 | 0 | 1 | 1 |
19.4.2.1.6 | Protein homeostasis.proteolysis.serine-type peptidase activities.S8-class protease (subtilisin) families.protease (SBT6.1) | 43 | 37 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.4.2.9.7 | Protein homeostasis.proteolysis.serine-type peptidase activities.chloroplast Clp-type protease complex.adaptor component ClpF | 43 | 36 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 1 |
19.2.3.1.1.13 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP27) | 42 | 31 | 2 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 4 | 3 | 2 | 1 | 0 | 3 | 0 | 2 | 1 |
19.3.3.5.1 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG12-ATG5 ATG8-PE-ligase E3 heterodimer.ubiquitin-fold component ATG12 | 42 | 32 | 1 | 1 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 3 | 4 | 1 | 1 | 2 | 1 | 0 | 1 | 1 |
19.4.2.8.1 | Protein homeostasis.proteolysis.serine-type peptidase activities.mitochondrion Clp-type protease complex.proteolytic component ClpP2 | 42 | 34 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 4 | 1 | 1 | 3 | 2 | 1 | 0 | 1 | 0 | 0 | 1 |
19.4.5.4.1 | Protein homeostasis.proteolysis.metallopeptidase activities.M16 families.peptidase (PQQL-like) | 42 | 32 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 3 | 1 | 2 | 0 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 0 |
19.2.1.2.1.4 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.N-terminal modification.Nt-asparagine amidase (NTAN) | 41 | 31 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 3 | 1 | 4 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.2.4.3.3 | Protein homeostasis.ubiquitin-proteasome system.ER-associated protein degradation (ERAD).substrate processing.deubiquinating protease (OTU1) | 41 | 31 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 3 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 4 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.3.3.6 | Protein homeostasis.autophagy.ATG8/ATG12 conjugation system.ATG12-conjugation E2 protein (ATG10) | 41 | 32 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 2 | 1 | 1 | 0 | 1 | 0 | 1 | 2 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 0 | 0 | 1 |
19.1.8.11 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-P protein | 39 | 27 | 2 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 3 | 1 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 2 | 4 | 3 | 1 | 1 | 1 | 0 | 1 | 0 |
19.2.1.2.1.3 | Protein homeostasis.ubiquitin-proteasome system.N-degron pathways.Arg/N-degron pathway.N-terminal modification.Nt-glutamine amidase (NTAQ) | 39 | 33 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 3 | 3 | 1 | 0 | 1 | 0 | 1 | 1 |
19.2.3.4 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.UFM deconjugation | 37 | 33 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 2 | 1 | 1 | 0 | 0 | 1 | 1 |
19.2.3.4.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.UFM deconjugation.UFM1-specific protease | 37 | 33 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 2 | 1 | 1 | 0 | 0 | 1 | 1 |
19.2.3.1.2.6 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.OTU deubiquitinase activities.deubiquitinase (OTU7) | 36 | 31 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 1 |
19.2.2.8.1.4.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.SKP1-CUL1-FBX (SCF) E3 ligase complexes.F-BOX substrate adaptor components.component UFO | 35 | 24 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 3 | 0 | 1 | 0 | 2 | 1 | 1 | 1 | 2 | 0 | 3 | 3 | 1 | 1 | 3 | 2 | 0 | 0 | 1 |
19.2.2.8.2.2.3 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.BTB/POZ substrate adaptor components.component FBL | 35 | 28 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 3 | 4 | 2 | 1 | 0 | 0 | 0 | 1 | 0 |
19.2.5.2 | Protein homeostasis.ubiquitin-proteasome system.chloroplast-associated protein degradation (CHLORAD).protein retrotranslocase (SP2) | 35 | 28 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 2 | 1 | 1 | 1 | 0 | 1 | 3 | 3 | 2 | 1 | 0 | 1 | 0 | 1 | 0 |
19.1.8.10 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-PX protein | 33 | 27 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 0 | 1 | 0 |
19.2.2.8.3.3.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL4-DDB1 ubiquitination complexes.COP10-DET1 (CDD) subcomplex.E2 conjugating component COP10 | 32 | 25 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 3 | 2 | 1 | 0 | 1 | 0 | 0 | 1 |
19.1.8.3 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-III protein | 31 | 26 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 2 | 1 | 3 | 1 | 0 | 1 | 0 |
19.2.2.8.2.2.1 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.BTB/POZ substrate adaptor components.component NPH3 | 31 | 22 | 1 | 1 | 1 | 0 | 1 | 1 | 3 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 2 | 0 | 1 | 0 | 2 | 1 | 1 | 2 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
19.2.3.1.1.11 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein deconjugation.ubiquitin deconjugation.UBP deubiquitinase activities.deubiquitinase (UBP25) | 23 | 18 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 2 | 1 | 0 | 1 | 2 | 0 | 1 | 1 | 2 | 0 | 3 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
19.3.4.4 | Protein homeostasis.autophagy.autophagic cargo receptor activities.adapter protein (ATI3) | 23 | 9 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 0 | 4 | 2 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
19.1.8.5 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-V protein | 18 | 15 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 2 | 2 | 1 | 2 | 0 | 1 | 0 | 1 | 0 |
19.1.8.9 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-M-II protein | 11 | 9 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
19.1.8.4 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-IV protein | 3 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
19.1.8.7 | Protein homeostasis.protein quality control.smallHsp holdase chaperone activities.class-C-VII protein | 3 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |