Gene: AT1G21710

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G21710
  • Transcript Identifier AT1G21710.1
  • Gene Type Coding gene
  • Location Chr1 : 7624439-7625869 : positive

Gene Family Information

  • ID HOM05D002121
  • #Genes/#Species 315/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G21710.1
  • symbol OGG1
  • Alias ATOGG1,ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1
  • uniprot Q9FNY7

Descriptions

  • Description 8-oxoguanine-DNA glycosylase 1
  • Computational description 8-oxoguanine-DNA glycosylase 1 (OGG1); FUNCTIONS IN: oxidized purine base lesion DNA N-glycosylase activity; INVOLVED IN: DNA repair, base-excision repair; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA glycosylase (InterPro:IPR011257), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Transcription factor TFIID, C-terminal/DNA glycosylase, N-terminal (InterPro:IPR012294), 8-oxoguanine DNA glycosylase, N-terminal (InterPro:IPR012904), HhH-GPD domain (InterPro:IPR003265); Has 951 Blast hits to 936 proteins in 417 species: Archae - 106; Bacteria - 332; Metazoa - 176; Fungi - 163; Plants - 46; Viruses - 0; Other Eukaryotes - 128 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051603
ISO
PLAZA Homology (enrichment)proteolysis involved in cellular protein catabolic process HOM05D002121
GO:0043161
ISO
PLAZA Homology (enrichment)proteasome-mediated ubiquitin-dependent protein catabolic process HOM05D002121
GO:0006289
IEA
Gene Ontologynucleotide-excision repair
GO:0006289
IEA
InterPronucleotide-excision repair
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IDA
Gene OntologyDNA repair1
GO:0006281
IEA
InterProDNA repair
GO:0006284
IEA
GOA Databasebase-excision repair
GO:0006284
IEA
InterProbase-excision repair
GO:0008152
IEA
GOA Databasemetabolic process
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006285
IBA
Gene Ontologybase-excision repair, AP site formation2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0008534
IEA
GOA Databaseoxidized purine nucleobase lesion DNA N-glycosylase activity
GO:0008534
IDA
Gene Ontologyoxidized purine nucleobase lesion DNA N-glycosylase activity1
GO:0008534
IEA
InterProoxidized purine nucleobase lesion DNA N-glycosylase activity
GO:0003684
IEA
Gene Ontologydamaged DNA binding
GO:0003684
IEA
InterProdamaged DNA binding
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0016798
IEA
GOA Databasehydrolase activity, acting on glycosyl bonds
GO:0016829
IEA
GOA Databaselyase activity
GO:0034039
IBA
Gene Ontology8-oxo-7,8-dihydroguanine DNA N-glycosylase activity2
GO:0140078
IEA
Gene Ontologyclass I DNA-(apurinic or apyrimidinic site) endonuclease activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019774
ISO
PLAZA Homology (enrichment)proteasome core complex, beta-subunit complex HOM05D002121
GO:0005839
ISO
PLAZA Homology (enrichment)proteasome core complex HOM05D002121
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM, IBA
Gene Ontologynucleus2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR003265 HhH-GPD domain
IPR023170 Helix-hairpin-helix, base-excision DNA repair, C-terminal
IPR011257 DNA glycosylase
IPR012904 8-oxoguanine DNA glycosylase, N-terminal
Mapman id Description
14.5.2 DNA damage response.base excision repair (BER).oxoguanine DNA glycosylase (OGG1)