Gene: Sopen08g021990
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen08g021990
- Transcript Identifier Sopen08g021990.1
- Gene Type Coding gene
- Location Spenn-ch08 : 61406375-61432235 : positive
Gene Family Information
- ID HOM05D003889
- #Genes/#Species 179/94
- Phylogenetic origin
- ID ORTHO05D004407
- #Genes/#Species 181/94
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid Sopen08g021990.1
Descriptions
- Description Encodes a homolog of Drosophila MUS308 and mammalian DNA polymerase, which prevent spontaneous or DNA damage-induced production of DNA double strand breaks. Two conserved functional domains: an N-terminal superfamily II DNA/RNA helicase domain and a C-terminal prokaryotic-type DNA polymerase I domain. Required for regulated cell division and differentiation in meristems. Mutant plants show morphological defects, such as short roots, serrated leaves, and fasciation, as well as defective patterns of cell division and differentiation in the meristem. Mutant plants had 2.5 to 4.5-fold higher expression of ATGR1, ATBRCA1 and RAD51 genes. TEB is required for normal progression of DNA replication and for correct expression of genes during development. | helicases, ATP-dependent helicases, nucleic acid binding, ATP binding, DNA-directed DNA polymerases, DNA binding | FUNCTIONS IN: in 6 functions | INVOLVED IN: regulation of gene expression, DNA replication, DNA recombination, photomorphogenesis | EXPRESSED IN: 6 plant structures | EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage | CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal , DEAD-like helicase, N-terminal , DNA-directed DNA polymerase, family A, palm domain , DNA/RNA helicase, C-terminal , DNA polymerase A domain , Helicase, superfamily 1/2, ATP-binding domain | BEST Arabidopsis thaliana protein match is: U5 small nuclear ribonucleoprotein helicase
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006261 | IEA | InterPro | DNA-dependent DNA replication | |
| GO:0006260 | IEA | InterPro | DNA replication | |
| GO:0051301 | ISO | PLAZA Integrative Orthology | cell division | AT4G32700 |
| GO:1990067 | ISO | PLAZA Integrative Orthology | intrachromosomal DNA recombination | AT4G32700 |
| GO:1902749 | ISO | PLAZA Integrative Orthology | regulation of cell cycle G2/M phase transition | AT4G32700 |
| GO:0009640 | ISO | PLAZA Integrative Orthology | photomorphogenesis | AT4G32700 |
| GO:0006310 | ISO | PLAZA Integrative Orthology | DNA recombination | AT4G32700 |
| GO:0010468 | ISO | PLAZA Integrative Orthology | regulation of gene expression | AT4G32700 |
| GO:2000011 | ISO | PLAZA Integrative Orthology | regulation of adaxial/abaxial pattern formation | AT4G32700 |
| GO:0009933 | ISO | PLAZA Integrative Orthology | meristem structural organization | AT4G32700 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0003887 | IEA | InterPro | DNA-directed DNA polymerase activity | |
| GO:0003677 | IEA | InterPro | DNA binding | |
| GO:0003676 | IEA | InterPro | nucleic acid binding | |
| GO:0005524 | IEA | InterPro | ATP binding |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR002298 | DNA polymerase A |
| IPR001098 | DNA-directed DNA polymerase, family A, palm domain |
| IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| IPR011545 | DEAD/DEAH box helicase domain |
| IPR001650 | Helicase, C-terminal |
| IPR036397 | Ribonuclease H superfamily |
| IPR043502 | DNA/RNA polymerase superfamily |
| Mapman id | Description |
|---|---|
| 14.2.2 | DNA damage response.DNA repair polymerase activities.DNA polymerase theta (TEB) |