InterPro domain: IPR001098

General Information

  • Identifier IPR001098
  • Description DNA-directed DNA polymerase, family A, palm domain

Abstract

Synonym(s): DNA nucleotidyltransferase (DNA-directed)

DNA-directed DNA polymerases( 2.7.7.7 ) are the key enzymes catalysing the accurate replication of DNA. They require either a small RNA molecule or a protein as a primer for the de novo synthesis of a DNA chain. A number of polymerases belong to this family [ 1 , 2 , 3 ].


1. An attempt to unify the structure of polymerases. Protein Eng. 3, 461-7
2. Compilation and alignment of DNA polymerase sequences. Nucleic Acids Res. 19, 4045-57
3. Compilation, alignment, and phylogenetic relationships of DNA polymerases. Nucleic Acids Res. 21, 787-802

Species distribution

Gene table