Gene: Sopen01g032530

General Information

Structural Information

  • Species Solanum pennellii
  • Gene Identifier Sopen01g032530
  • Transcript Identifier Sopen01g032530.2
  • Gene Type Coding gene
  • Location Spenn-ch01 : 90371442-90374974 : positive

Gene Family Information

  • ID HOM05D006268
  • #Genes/#Species 127/98
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid Sopen01g032530.2

Descriptions

  • Description Encodes a transthyretin-like S-allantoin synthase protein that catalyzes two steps in the allantoin biosynthesis pathway by acting as a hydroxyisourate hydrolase and a 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase. Two alternatively spliced versions of the transcript give rise to a longer peroxisomally-targeted protein (AT5G58220.1 (called TTL1-)) and a slightly shorter cytoplasmic protein (AT5G58220.3 (called TTL2-)). Both have roughly equivalent enzymatic activity in vitro, but, allantoin biosynthesis is believed to occur in the peroxisome suggesting that the cytosolic form may participate in a different process. | transthyretin-like protein (TTL) | FUNCTIONS IN: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity, hydroxyisourate hydrolase activity | INVOLVED IN: regulation of cell growth by extracellular stimulus, brassinosteroid mediated signaling pathway, protein homotetramerization | LOCATED IN: cytosol, extrinsic to internal side of plasma membrane, peroxisome | EXPRESSED IN: 22 plant structures | EXPRESSED DURING: 13 growth stages | CONTAINS InterPro DOMAIN/s: Bifunctional hydroxyisourate hydrolase/2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase , Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase , Hydroxyisourate hydrolase , Transthyretin/hydroxyisourate hydrolase
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006144
IEA
InterPropurine nucleobase metabolic process
GO:0019428
ISO
PLAZA Integrative Orthologyallantoin biosynthetic process AT5G58220
GO:0009742
ISO
PLAZA Integrative Orthologybrassinosteroid mediated signaling pathway AT5G58220
GO:0001560
ISO
PLAZA Integrative Orthologyregulation of cell growth by extracellular stimulus AT5G58220

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0033971
IEA
InterProhydroxyisourate hydrolase activity
GO:0042802
ISO
PLAZA Integrative Orthologyidentical protein binding AT5G58220
GO:0005515
ISO
PLAZA Integrative Orthologyprotein binding AT5G58220
GO:0051997
ISO
PLAZA Integrative Orthology2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity AT5G58220

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005777
ISO
PLAZA Integrative Orthologyperoxisome AT5G58220
GO:0031234
ISO
PLAZA Integrative Orthologyextrinsic component of cytoplasmic side of plasma membrane AT5G58220
GO:0005829
ISO
PLAZA Integrative Orthologycytosol AT5G58220

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR023416 Transthyretin/hydroxyisourate hydrolase domain
IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily
IPR014306 Hydroxyisourate hydrolase
IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily
IPR000895 Transthyretin/hydroxyisourate hydrolase
IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Mapman id Description
6.1.5.6 Nucleotide metabolism.purines.catabolism.S-allantoin synthase (TTL)