InterPro domain: IPR018020
General Information
- Identifier IPR018020
- Description Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
- Number of genes 112
- Gene duplication stats Loading...
Abstract
The proteins in this entry are OHCU decarboxylase, an enzyme of the purine catabolism that catalyses the conversion of OHCU into S(+)-allantoin [ 1 ]; it is the third step of the conversion of uric acid (a purine derivative) to allantoin. Step one is catalysed by urate oxidase ( IPR002042 ) and step two is catalysed by hydroxyisourate hydrolase ( IPR000895 ).
1. Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes. Nat. Chem. Biol. 2, 144-8
Species distribution
Gene table
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