Gene: AT5G58220
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT5G58220
- Transcript Identifier AT5G58220.3
- Gene Type Coding gene
- Location Chr5 : 23554546-23555861 : negative
Gene Family Information
- ID HOM05D006268
- #Genes/#Species 127/98
- Phylogenetic origin
- ID ORTHO05D008118
- #Genes/#Species 123/97
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT5G58220.3
- symbol TTL
- Alias ALNS,allantoin synthase
- uniprot Q9LVM5
Descriptions
- Description transthyretin-like protein
- Computational description transthyretin-like protein (TTL); FUNCTIONS IN: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity, hydroxyisourate hydrolase activity; INVOLVED IN: regulation of cell growth by extracellular stimulus, brassinosteroid mediated signaling pathway, protein homotetramerization, allantoin biosynthetic process; LOCATED IN: extrinsic to internal side of plasma membrane, peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Bifunctional hydroxyisourate hydrolase/2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR017129), Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR018020), Hydroxyisourate hydrolase (InterPro:IPR014306), Transthyretin/hydroxyisourate hydrolase (InterPro:IPR000895); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
- Computational description transthyretin-like protein (TTL); FUNCTIONS IN: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity, hydroxyisourate hydrolase activity; INVOLVED IN: regulation of cell growth by extracellular stimulus, brassinosteroid mediated signaling pathway, protein homotetramerization; LOCATED IN: cytosol, extrinsic to internal side of plasma membrane, peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Bifunctional hydroxyisourate hydrolase/2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR017129), Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR018020), Hydroxyisourate hydrolase (InterPro:IPR014306), Transthyretin/hydroxyisourate hydrolase (InterPro:IPR000895); Has 3236 Blast hits to 3236 proteins in 817 species: Archae - 6; Bacteria - 1906; Metazoa - 529; Fungi - 103; Plants - 58; Viruses - 0; Other Eukaryotes - 634 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006144 | IEA | GOA Database | purine nucleobase metabolic process | |
| GO:0006144 | IBA | Gene Ontology | purine nucleobase metabolic process | 1 |
| GO:0006144 | IEA | InterPro | purine nucleobase metabolic process | |
| GO:0008152 | IEA | GOA Database | metabolic process | |
| GO:0019428 | IDA | Gene Ontology | allantoin biosynthetic process | 2 |
| GO:0009742 | IMP | Gene Ontology | brassinosteroid mediated signaling pathway | 3 |
| GO:0001560 | IMP | Gene Ontology | regulation of cell growth by extracellular stimulus | 3 |
| GO:0019628 | IEA | Gene Ontology | urate catabolic process |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0033971 | IEA | GOA Database | hydroxyisourate hydrolase activity | |
| GO:0033971 | IDA | Gene Ontology | hydroxyisourate hydrolase activity | 2 |
| GO:0033971 | IEA | InterPro | hydroxyisourate hydrolase activity | |
| GO:0016787 | IEA | GOA Database | hydrolase activity | |
| GO:0016829 | IEA | GOA Database | lyase activity | |
| GO:0016831 | IEA | GOA Database | carboxy-lyase activity | |
| GO:0003824 | IEA | GOA Database | catalytic activity | |
| GO:0051997 | IEA | GOA Database | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity | |
| GO:0051997 | IDA | Gene Ontology | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity | 2 |
| GO:0042802 | IPI | Gene Ontology | identical protein binding | 4 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 3 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0016020 | IEA | GOA Database | membrane | |
| GO:0005886 | IEA | GOA Database | plasma membrane | |
| GO:0005777 | IEA | GOA Database | peroxisome | |
| GO:0005777 | IDA, HDA | Gene Ontology | peroxisome | 2 5 |
| GO:0005576 | ISM | Gene Ontology | extracellular region | |
| GO:0005829 | IDA | Gene Ontology | cytosol | 2 |
| GO:0031234 | IDA | Gene Ontology | extrinsic component of cytoplasmic side of plasma membrane | 3 |
| GO:0005634 | ISM | Gene Ontology | nucleus |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR018020 | Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase |
| IPR023416 | Transthyretin/hydroxyisourate hydrolase domain |
| IPR036817 | Transthyretin/hydroxyisourate hydrolase domain superfamily |
| IPR014306 | Hydroxyisourate hydrolase |
| IPR036778 | Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily |
| IPR000895 | Transthyretin/hydroxyisourate hydrolase |
| Mapman id | Description |
|---|---|
| 6.1.5.6 | Nucleotide metabolism.purines.catabolism.S-allantoin synthase (TTL) |