Gene: AT4G12740

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G12740
  • Transcript Identifier AT4G12740.2
  • Gene Type Coding gene
  • Location Chr4 : 7494711-7497596 : negative

Gene Family Information

  • ID HOM05D006570
  • #Genes/#Species 122/94
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G12740.2
  • uniprot F4JRF4

Descriptions

  • Description HhH-GPD base excision DNA repair family protein
  • Computational description HhH-GPD base excision DNA repair family protein; FUNCTIONS IN: hydrolase activity, catalytic activity; INVOLVED IN: DNA repair, base-excision repair; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), DNA glycosylase (InterPro:IPR011257), NUDIX hydrolase domain (InterPro:IPR000086), HhH-GPD domain (InterPro:IPR003265); Has 55833 Blast hits to 29061 proteins in 2861 species: Archae - 372; Bacteria - 10631; Metazoa - 17750; Fungi - 4523; Plants - 1695; Viruses - 834; Other Eukaryotes - 20028 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IEA
InterProDNA repair
GO:0006284
IEA
GOA Databasebase-excision repair
GO:0006284
IBA
Gene Ontologybase-excision repair1
GO:0006284
IEA
InterProbase-excision repair
GO:0008152
IEA
GOA Databasemetabolic process
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006298
IBA
Gene Ontologymismatch repair1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051536
IEA
GOA Databaseiron-sulfur cluster binding
GO:0003677
ISO
PLAZA Homology (enrichment)DNA binding HOM05D006570
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0016798
IEA
GOA Databasehydrolase activity, acting on glycosyl bonds
GO:0016798
IEA
InterProhydrolase activity, acting on glycosyl bonds
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0000701
IBA
IEA
Gene Ontologypurine-specific mismatch base pair DNA N-glycosylase activity1
GO:0051539
IEA
GOA Database4 iron, 4 sulfur cluster binding
GO:0034039
IBA
Gene Ontology8-oxo-7,8-dihydroguanine DNA N-glycosylase activity1
GO:0035485
IBA
Gene Ontologyadenine/guanine mispair binding1
GO:0032357
IBA
Gene Ontologyoxidized purine DNA binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM, IBA
Gene Ontologynucleus1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR003265 HhH-GPD domain
IPR023170 Helix-hairpin-helix, base-excision DNA repair, C-terminal
IPR044298 Adenine/Thymine-DNA glycosylase
IPR029119 MutY, C-terminal
IPR011257 DNA glycosylase
IPR015797 NUDIX hydrolase-like domain superfamily
Mapman id Description
35.1 not assigned.annotated