Gene: AT4G02460

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G02460
  • Transcript Identifier AT4G02460.2
  • Gene Type Coding gene
  • Location Chr4 : 1077047-1080510 : negative

Gene Family Information

  • ID HOM05D002199
  • #Genes/#Species 305/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G02460.2
  • symbol PMS1
  • Alias AtPMS1
  • full_name POSTMEIOTIC SEGREGATION 1
  • uniprot Q941I6

Descriptions

  • Description DNA mismatch repair protein
  • Computational description POSTMEIOTIC SEGREGATION 1 (PMS1); FUNCTIONS IN: mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, fruit development, seed development, DNA recombination, pollen development; LOCATED IN: nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair, conserved site (InterPro:IPR014762), ATPase-like, ATP-binding domain (InterPro:IPR003594), DNA mismatch repair protein, C-terminal (InterPro:IPR013507), MutL, C-terminal, dimerisation (InterPro:IPR014790), DNA mismatch repair protein, N-terminal (InterPro:IPR014763), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), DNA mismatch repair protein (InterPro:IPR002099), Post Meiotic Segregation 2 (InterPro:IPR015434), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721); BEST Arabidopsis thaliana protein match is: MUTL-homologue 1 (TAIR:AT4G09140.1); Has 10471 Blast hits to 7086 proteins in 2377 species: Archae - 138; Bacteria - 7516; Metazoa - 568; Fungi - 666; Plants - 148; Viruses - 0; Other Eukaryotes - 1435 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000398
ISO
PLAZA Homology (enrichment)mRNA splicing, via spliceosome HOM05D002199
GO:0006396
ISO
PLAZA Homology (enrichment)RNA processing HOM05D002199
GO:0000956
ISO
PLAZA Homology (enrichment)nuclear-transcribed mRNA catabolic process HOM05D002199
GO:0006298
IMP
IBA
IEA
Gene Ontologymismatch repair1 2
GO:0006298
IEA
InterPromismatch repair
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0048316
IMP
Gene Ontologyseed development3
GO:0010154
IMP
Gene Ontologyfruit development3
GO:0009555
IMP
Gene Ontologypollen development3
GO:0006310
IMP
Gene OntologyDNA recombination3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016887
IBA
Gene OntologyATP hydrolysis activity2
GO:0016887
IEA
InterProATP hydrolysis activity
GO:0030983
IEA
Gene Ontologymismatched DNA binding
GO:0030983
IEA
InterPromismatched DNA binding
GO:0005524
IEA
Gene OntologyATP binding
GO:0005524
IEA
InterProATP binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0032300
IBA
IEA
Gene Ontologymismatch repair complex2
GO:0032300
IEA
InterPromismatch repair complex
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
IC
Gene Ontologynucleus3
GO:0032389
IBA
Gene OntologyMutLalpha complex2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR014790 MutL, C-terminal, dimerisation
IPR013507 DNA mismatch repair protein, S5 domain 2-like
IPR036890 Histidine kinase/HSP90-like ATPase superfamily
IPR002099 DNA mismatch repair protein family, N-terminal
IPR037198 MutL, C-terminal domain superfamily
IPR042120 MutL, C-terminal domain, dimerisation subdomain
IPR038973 DNA mismatch repair protein MutL/Mlh/Pms
IPR020568 Ribosomal protein S5 domain 2-type fold
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
Mapman id Description
14.7.2.2 DNA damage response.mismatch repair (MMR).MLH1-PMS1 heterodimer.component PMS1