Gene: AT3G25530

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G25530
  • Transcript Identifier AT3G25530.1
  • Gene Type Coding gene
  • Location Chr3 : 9271949-9273514 : negative

Gene Family Information

  • ID HOM05D001008
  • #Genes/#Species 601/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G25530.1
  • symbol GLYR1
  • Alias ATGHBDH,AtGLYR1,GHBDH,GR1,GLYOXYLATE REDUCTASE 1
  • uniprot Q9LSV0

Descriptions

  • Description glyoxylate reductase 1
  • Computational description glyoxylate reductase 1 (GLYR1); FUNCTIONS IN: 3-hydroxybutyrate dehydrogenase activity, phosphogluconate dehydrogenase (decarboxylating) activity; INVOLVED IN: response to oxidative stress; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), 6-phosphogluconate dehydrogenase (InterPro:IPR006183), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: glyoxylate reductase 2 (TAIR:AT1G17650.1); Has 17561 Blast hits to 17531 proteins in 2324 species: Archae - 147; Bacteria - 10853; Metazoa - 400; Fungi - 503; Plants - 354; Viruses - 5; Other Eukaryotes - 5299 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009448
ISO
PLAZA Integrative Orthologygamma-aminobutyric acid metabolic process Solyc09g018790.3
GO:0006979
IMP
Gene Ontologyresponse to oxidative stress1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016616
IBA
Gene Ontologyoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor2
GO:0051287
IEA
Gene OntologyNAD binding
GO:0051287
IEA
InterProNAD binding
GO:0050661
IEA
Gene OntologyNADP binding
GO:0050661
IEA
InterProNADP binding
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0003858
IMP
IBA
Gene Ontology3-hydroxybutyrate dehydrogenase activity1 2
GO:0030267
IEA
Gene Ontologyglyoxylate reductase (NADP+) activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005829
IEA
GOA Databasecytosol
GO:0005829
IDA, HDA
IBA
Gene Ontologycytosol2 3 4
GO:0005634
ISM
Gene Ontologynucleus
GO:0005739
ISM
Gene Ontologymitochondrion

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036291 NAD(P)-binding domain superfamily
IPR013328 6-phosphogluconate dehydrogenase, domain 2
IPR015815 3-hydroxyisobutyrate dehydrogenase-related
IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain
Mapman id Description
4.2.2.3.1 Amino acid metabolism.degradation.gamma-aminobutyrate (GABA).gamma-hydroxybutyrate formation.bifunctional gamma-hydroxybutyrate dehydrogenase and glyoxylate reductase