Gene: AT2G31450

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G31450
  • Transcript Identifier AT2G31450.2
  • Gene Type Coding gene
  • Location Chr2 : 13401318-13404134 : negative

Gene Family Information

  • ID HOM05D004358
  • #Genes/#Species 164/94
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G31450.2
  • symbol ATNTH1
  • uniprot Q9SIC4

Descriptions

  • Description DNA glycosylase superfamily protein
  • Computational description ATNTH1; CONTAINS InterPro DOMAIN/s: Helix-hairpin-helix motif (InterPro:IPR000445), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Endonuclease III, iron-sulphur binding site (InterPro:IPR004035), DNA glycosylase (InterPro:IPR011257), Endonuclease III-like, iron-sulphur cluster loop motif (InterPro:IPR003651), Endonuclease III, conserved site-2 (InterPro:IPR004036), HhH-GPD domain (InterPro:IPR003265); BEST Arabidopsis thaliana protein match is: endonuclease III 2 (TAIR:AT1G05900.2); Has 14067 Blast hits to 14061 proteins in 2669 species: Archae - 367; Bacteria - 9308; Metazoa - 224; Fungi - 193; Plants - 158; Viruses - 0; Other Eukaryotes - 3817 (source: NCBI BLink).
  • Computational description ATNTH1; CONTAINS InterPro DOMAIN/s: Helix-hairpin-helix motif (InterPro:IPR000445), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Endonuclease III, iron-sulphur binding site (InterPro:IPR004035), DNA glycosylase (InterPro:IPR011257), Endonuclease III-like, iron-sulphur cluster loop motif (InterPro:IPR003651), Endonuclease III, conserved site-2 (InterPro:IPR004036), HhH-GPD domain (InterPro:IPR003265); BEST Arabidopsis thaliana protein match is: endonuclease III 2 (TAIR:AT1G05900.2); Has 14133 Blast hits to 14127 proteins in 2683 species: Archae - 365; Bacteria - 9377; Metazoa - 224; Fungi - 192; Plants - 158; Viruses - 0; Other Eukaryotes - 3817 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IEA
InterProDNA repair
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0008152
IEA
GOA Databasemetabolic process
GO:0006284
IEA
GOA Databasebase-excision repair
GO:0006284
IDA
Gene Ontologybase-excision repair1
GO:0006284
IEA
InterProbase-excision repair
GO:0006285
IEA
GOA Databasebase-excision repair, AP site formation
GO:0006285
IBA
Gene Ontologybase-excision repair, AP site formation2
GO:0006296
IBA
Gene Ontologynucleotide-excision repair, DNA incision, 5'-to lesion2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0051536
IEA
GOA Databaseiron-sulfur cluster binding
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0016829
IEA
GOA Databaselyase activity
GO:0016798
IEA
GOA Databasehydrolase activity, acting on glycosyl bonds
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0019104
IEA
GOA DatabaseDNA N-glycosylase activity
GO:0019104
IDA
Gene OntologyDNA N-glycosylase activity1
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0051539
IEA
GOA Database4 iron, 4 sulfur cluster binding
GO:0051539
IEA
InterPro4 iron, 4 sulfur cluster binding
GO:0140078
IEA
Gene Ontologyclass I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0003906
IEA
GOA DatabaseDNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0003906
IDA
IBA
Gene OntologyDNA-(apurinic or apyrimidinic site) endonuclease activity1 2
GO:0000703
IEA
GOA Databaseoxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0000703
IBA
Gene Ontologyoxidized pyrimidine nucleobase lesion DNA N-glycosylase activity2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IEA
GOA Databasechloroplast
GO:0009536
IEA
GOA Databaseplastid
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM, IBA
Gene Ontologynucleus2
GO:0005739
ISM
Gene Ontologymitochondrion
GO:0042644
IEA
GOA Databasechloroplast nucleoid
GO:0042644
IDA
IBA
Gene Ontologychloroplast nucleoid2 3

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR003265 HhH-GPD domain
IPR000445 Helix-hairpin-helix motif
IPR011257 DNA glycosylase
IPR023170 Helix-hairpin-helix, base-excision DNA repair, C-terminal
IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif
Mapman id Description
14.5.11 DNA damage response.base excision repair (BER).bifunctional glycosylase-lyase and endonuclease (NTH)