Gene: AT2G27040

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G27040
  • Transcript Identifier AT2G27040.1
  • Gene Type Coding gene
  • Location Chr2 : 11536795-11541503 : negative

Gene Family Information

  • ID HOM05D000234
  • #Genes/#Species 1784/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G27040.1
  • symbol AGO4
  • Alias OCP11,OVEREXPRESSOR OF CATIONIC PEROXIDASE 11
  • full_name ARGONAUTE 4
  • uniprot Q9ZVD5

Descriptions

  • Description Argonaute family protein
  • Computational description ARGONAUTE 4 (AGO4); FUNCTIONS IN: siRNA binding; INVOLVED IN: in 6 processes; LOCATED IN: nuclear euchromatin, nucleolus, Cajal body; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Domain of unknown function DUF1785 (InterPro:IPR014811), Stem cell self-renewal protein Piwi (InterPro:IPR003165), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); BEST Arabidopsis thaliana protein match is: Argonaute family protein (TAIR:AT5G21150.1); Has 1929 Blast hits to 1875 proteins in 205 species: Archae - 0; Bacteria - 0; Metazoa - 1009; Fungi - 290; Plants - 478; Viruses - 0; Other Eukaryotes - 152 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030422
IMP, IGI
Gene Ontologyproduction of siRNA involved in RNA interference1 2
GO:0080188
IMP
GOA Databasegene silencing by RNA-directed DNA methylation
GO:0070919
IMP
GOA Databaseproduction of siRNA involved in chromatin silencing by small RNA
GO:0090502
IEA
GOA DatabaseRNA phosphodiester bond hydrolysis, endonucleolytic
GO:0051607
IDA
Gene Ontologydefense response to virus3
GO:0006417
IEA
GOA Databaseregulation of translation
GO:0006952
IEA
GOA Databasedefense response
GO:0031047
IEA
GOA Databasegene silencing by RNA
GO:0031048
TAS
Gene Ontologyheterochromatin assembly by small RNA4
GO:0006342
IMP
Gene Ontologychromatin silencing5
GO:0051567
IMP
Gene Ontologyhistone H3-K9 methylation6
GO:0006306
IMP
Gene OntologyDNA methylation7
GO:0010495
IMP
Gene Ontologylong-distance posttranscriptional gene silencing8
GO:0042742
IMP
Gene Ontologydefense response to bacterium4
GO:0016458
IMP
Gene Ontologygene silencing9
GO:0019048
IMP
Gene Ontologymodulation by virus of host process10

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004521
IMP
Gene Ontologyendoribonuclease activity2
GO:0035198
IDA
GOA DatabasemiRNA binding
GO:0035197
IMP
GOA DatabasesiRNA binding
GO:0035197
IDA
Gene OntologysiRNA binding11
GO:0003723
IEA
GOA DatabaseRNA binding
GO:0003676
IEA
GOA Databasenucleic acid binding
GO:0003676
IEA
InterPronucleic acid binding
GO:0005515
IPI
Gene Ontologyprotein binding6
GO:0005515
IEA
InterProprotein binding
GO:0003682
IDA
Gene Ontologychromatin binding9

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0015030
IEA
GOA DatabaseCajal body
GO:0015030
IDA
Gene OntologyCajal body6
GO:0005654
IEA
GOA Databasenucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm12
GO:0005730
IEA
GOA Databasenucleolus
GO:0005730
IDA
Gene Ontologynucleolus13
GO:0005634
IEA
GOA Databasenucleus
GO:0000791
IDA
Gene Ontologyeuchromatin6
GO:0005737
ISM
Gene Ontologycytoplasm
GO:0005829
RCA
Gene Ontologycytosol14

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR014811 Argonaute, linker 1 domain
IPR036397 Ribonuclease H superfamily
IPR036085 PAZ domain superfamily
IPR003100 PAZ domain
IPR003165 Piwi domain
IPR032474 Protein argonaute, N-terminal
IPR032473 Protein argonaute, Mid domain
IPR032472 Argonaute linker 2 domain
IPR012337 Ribonuclease H-like superfamily
Mapman id Description
12.5.1.13 Chromatin organisation.DNA methylation.RNA-directed DNA methylation (RdDM) pathway.siRNA-integrating factor (AGO)