Gene: AT1G59900

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G59900
  • Transcript Identifier AT1G59900.1
  • Gene Type Coding gene
  • Location Chr1 : 22051368-22053660 : positive

Gene Family Information

  • ID HOM05D001355
  • #Genes/#Species 463/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G59900.1
  • symbol E1 ALPHA
  • Alias AT-E1 ALPHA,pyruvate dehydrogenase complex E1 alpha subunit
  • uniprot P52901

Descriptions

  • Description pyruvate dehydrogenase complex E1 alpha subunit
  • Computational description pyruvate dehydrogenase complex E1 alpha subunit (E1 ALPHA); FUNCTIONS IN: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, pyruvate dehydrogenase (acetyl-transferring) activity; INVOLVED IN: response to cadmium ion, metabolic process; LOCATED IN: cytosol, mitochondrion, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dehydrogenase, E1 component (InterPro:IPR001017), Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y (InterPro:IPR017597); BEST Arabidopsis thaliana protein match is: Thiamin diphosphate-binding fold (THDP-binding) superfamily protein (TAIR:AT1G24180.1); Has 9893 Blast hits to 9890 proteins in 1845 species: Archae - 125; Bacteria - 6023; Metazoa - 522; Fungi - 292; Plants - 213; Viruses - 0; Other Eukaryotes - 2718 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0010468
ISO
PLAZA Integrative Orthologyregulation of gene expression Zm00001eb194780
GO:0006626
ISO
PLAZA Integrative Orthologyprotein targeting to mitochondrion Zm00001eb194780
GO:0006086
IBA
IEA
Gene Ontologyacetyl-CoA biosynthetic process from pyruvate1
GO:0006086
IEA
InterProacetyl-CoA biosynthetic process from pyruvate
GO:0006096
IEA
GOA Databaseglycolytic process
GO:0046686
IEP
Gene Ontologyresponse to cadmium ion2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004739
IBA
IEA
Gene Ontologypyruvate dehydrogenase (acetyl-transferring) activity1
GO:0004739
IEA
InterPropyruvate dehydrogenase (acetyl-transferring) activity
GO:0016624
IEA
GOA Databaseoxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0016624
IEA
InterProoxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0016491
IEA
GOA Databaseoxidoreductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IDA
GOA Databasecytosol
GO:0005829
HDA
Gene Ontologycytosol3
GO:0043231
IEA
Gene Ontologyintracellular membrane-bounded organelle
GO:0043231
IEA
InterProintracellular membrane-bounded organelle
GO:0005739
IDA
IEA
GOA Databasemitochondrion
GO:0005739
HDA
Gene Ontologymitochondrion4
GO:0005634
IDA
GOA Databasenucleus
GO:0005634
HDA
Gene Ontologynucleus5
GO:0005759
IEA
GOA Databasemitochondrial matrix
GO:0009507
ISM
Gene Ontologychloroplast

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001017 Dehydrogenase, E1 component
IPR029061 Thiamin diphosphate-binding fold
IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
Mapman id Description
2.2.1.1.1 Cellular respiration.pyruvate oxidation.mitochondrial pyruvate dehydrogenase complex.component E1 heterodimer.subunit alpha