Gene: AT1G22940

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G22940
  • Transcript Identifier AT1G22940.1
  • Gene Type Coding gene
  • Location Chr1 : 8122384-8124908 : positive

Gene Family Information

  • ID HOM05D005536
  • #Genes/#Species 139/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G22940.1
  • symbol TH1
  • Alias TH-1,THIE,THIAMINEE
  • full_name THIAMINE REQUIRING 1
  • uniprot Q5M731

Descriptions

  • Description thiamin biosynthesis protein
  • Computational description THIAMINE REQUIRING 1 (TH1); FUNCTIONS IN: phosphomethylpyrimidine kinase activity, thiamin-phosphate diphosphorylase activity, hydroxymethylpyrimidine kinase activity; INVOLVED IN: thiamin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiamine monophosphate synthase (InterPro:IPR003733), Phosphomethylpyrimidine kinase type-2 (InterPro:IPR004399), Aldolase-type TIM barrel (InterPro:IPR013785), Phosphomethylpyrimidine kinase type-1 (InterPro:IPR013749); Has 15989 Blast hits to 15891 proteins in 2548 species: Archae - 338; Bacteria - 12149; Metazoa - 165; Fungi - 331; Plants - 107; Viruses - 0; Other Eukaryotes - 2899 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016310
IEA
GOA Databasephosphorylation
GO:0008152
IEA
GOA Databasemetabolic process
GO:0009228
IEA
GOA Databasethiamine biosynthetic process
GO:0009228
IMP
IBA
Gene Ontologythiamine biosynthetic process1 2
GO:0009228
IEA
InterProthiamine biosynthetic process
GO:0009229
IEA
Gene Ontologythiamine diphosphate biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016740
IEA
GOA Databasetransferase activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0016301
IEA
GOA Databasekinase activity
GO:0008972
IEA
GOA Databasephosphomethylpyrimidine kinase activity
GO:0008972
IGI
IBA
Gene Ontologyphosphomethylpyrimidine kinase activity1 2
GO:0008972
IEA
InterProphosphomethylpyrimidine kinase activity
GO:0004789
IEA
GOA Databasethiamine-phosphate diphosphorylase activity
GO:0004789
IDA, IGI
Gene Ontologythiamine-phosphate diphosphorylase activity1 3
GO:0004789
IEA
InterProthiamine-phosphate diphosphorylase activity
GO:0008902
IEA
GOA Databasehydroxymethylpyrimidine kinase activity
GO:0008902
IGI
IBA
Gene Ontologyhydroxymethylpyrimidine kinase activity1 2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma4
GO:0009536
IEA
GOA Databaseplastid
GO:0009507
IEA
GOA Databasechloroplast
GO:0009507
IDA, HDA
ISM, IBA
Gene Ontologychloroplast1 2 5
GO:0005829
IBA
Gene Ontologycytosol2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR022998 Thiamine phosphate synthase/TenI
IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase
IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase domain
IPR029056 Ribokinase-like
IPR034291 Thiamine phosphate synthase
IPR013785 Aldolase-type TIM barrel
IPR045029 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
IPR036206 Thiamin phosphate synthase superfamily
Mapman id Description
7.2.1.2 Coenzyme metabolism.thiamine pyrophosphate biosynthesis.hydroxymethylpyrimidine diphosphate biosynthesis.bifunctional hydroxymethylpyrimidine kinase and thiamine-phosphate diphosphorylase (Th1)