Gene: Sopen07g034150

General Information

Structural Information

  • Species Solanum pennellii
  • Gene Identifier Sopen07g034150
  • Transcript Identifier Sopen07g034150.1
  • Gene Type Coding gene
  • Location Spenn-ch07 : 78738089-78747202 : positive

Gene Family Information

  • ID HOM05D001876
  • #Genes/#Species 351/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid Sopen07g034150.1

Descriptions

  • Description Encodes VCS (VARICOSE). Involved in mRNA decapping. VCS forms a mRNA decapping complex with DCP1 (At1g08370) and DCP2 (At5g13570). Unlike DCP2, VCS itself does not have mRNA decapping activity in vitro. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. VCS is also required for leaf development. | VARICOSE (VCS) | FUNCTIONS IN: protein homodimerization activity, nucleotide binding | INVOLVED IN: mRNA catabolic process, deadenylation-independent decapping of nuclear-transcribed mRNA, leaf morphogenesis | LOCATED IN: cytosol, nucleus, cytoplasmic mRNA processing body | EXPRESSED IN: whole plant, guard cell, cultured cell | CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain , WD40 repeat 2 , WD40-repeat-containing domain , WD40/YVTN repeat-like-containing domain , WD40 repeat , WD40 repeat, subgroup | BEST Arabidopsis thaliana protein match is: varicose-related
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031087
IEA
InterProdeadenylation-independent decapping of nuclear-transcribed mRNA
GO:0010071
ISO
PLAZA Integrative Orthologyroot meristem specification AT3G13300
GO:0071365
ISO
PLAZA Integrative Orthologycellular response to auxin stimulus AT3G13300
GO:0010072
ISO
PLAZA Integrative Orthologyprimary shoot apical meristem specification AT3G13300
GO:0009791
ISO
PLAZA Integrative Orthologypost-embryonic development AT3G13300
GO:0006402
ISO
PLAZA Integrative OrthologymRNA catabolic process AT3G13300
GO:0009965
ISO
PLAZA Integrative Orthologyleaf morphogenesis AT3G13300

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IEA
InterProprotein binding
GO:0042803
ISO
PLAZA Integrative Orthologyprotein homodimerization activity AT3G13300
GO:0003729
ISO
PLAZA Integrative OrthologymRNA binding AT3G13300

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
PLAZA Integrative Orthologynucleus AT3G13300
GO:0000932
ISO
PLAZA Integrative OrthologyP-body AT3G13300
GO:0005829
ISO
PLAZA Integrative Orthologycytosol AT3G13300

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR044938 Enhancer of mRNA-decapping protein 4, conserved C-terminal domain
IPR036322 WD40-repeat-containing domain superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamily
IPR001680 WD40 repeat
IPR032401 Enhancer of mRNA-decapping protein 4, WD40 repeat region
IPR045152 Enhancer of mRNA-decapping protein 4-like
Mapman id Description
16.4.2.2.4 RNA processing.RNA surveillance.mRNA deadenylation-dependent decay.mRNA decapping complex.scaffold component VCS