Gene: Sopen06g034760

General Information

Description Encodes a member of the R protein complex and may represent a virulence target of type III pili effector proteins (virulence factors) from bacterial pathogens, which is guarded by R protein complex (RPM1 and RPS2 proteins). RIN4 physically interacts with RPS2 and RPM1 in vivo. Bacterial avirulence (Avr) effectors AvrB, AvrRpm1, and AvrRpt2 induce a mobility shift in RIN4 and expression of AvrRpt2 induces rapid degradation of RIN4. RIN4 contains 2 sites for AvrRpt2 autocleavage, called RCS1 and RCS2. Overexpression of RIN4 inhibits multiple phenotypes associated with AvrRpt2 function and also inhibits PAMP-induced defense signaling. Attached to the plasma membrane at its carboxyl terminus. Cleaved by AvrRpt2 at two PxFGxW motifs, one releasing a large portion of RIN4 from the plasma membrane and both exposing amino-terminal residues that destabilized the carboxyl-terminal cleavage products by targeting them for N-end ubiquitylation and proteasomal degradation. Major virulence target of the TTSE HopF2Pto. | RPM1 interacting protein 4 (RIN4) | FUNCTIONS IN: protein binding | INVOLVED IN: in 6 processes | LOCATED IN: plasma membrane, membrane | EXPRESSED IN: 22 plant structures | EXPRESSED DURING: 13 growth stages | CONTAINS InterPro DOMAIN/s: RPM1-interacting protein 4, defence response | BEST Arabidopsis thaliana protein match is: defense protein-related

No GO associations found for this gene.

InterPro	Description
IPR008700	RIN4, pathogenic type III effector avirulence factor Avr cleavage site
IPR040387	RPM1-interacting protein 4/NOI4

Mapman id	Description
26.9.2.2.2	External stimuli response.pathogen.effector-triggered immunity (ETI) network.RIN4-RPM1 immune signalling.RPM1-interacting factor (RIN4)