Gene: Sopen03g005140

General Information

Description Encodes a member of the DREB subfamily A-1 of ERF/AP2 transcription factor family (CBF2). The protein contains one AP2 domain. There are six members in this subfamily, including CBF1, CBF2, and CBF3. This gene is involved in response to low temperature, abscisic acid, and circadian rhythm. Overexpressing this gene leads to increased freeze tolerance and induces the expression level of 85 cold-induced genes and reduces the expression level of 8 cold-repressed genes, which constitute the CBF2 regulon. Mutations in CBF2 increases the expression level of CBF1 and CBF3, suggesting that this gene may be involved in a negative regulatory or feedback circuit of the CBF pathway. | C-repeat/DRE binding factor 2 (CBF2) | CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type , Pathogenesis-related transcriptional factor/ERF, DNA-binding | BEST Arabidopsis thaliana protein match is: C-repeat/DRE binding factor 1

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0009414	ISO	PLAZA Integrative Orthology	response to water deprivation	AT1G12610
GO:0050826	ISO	PLAZA Integrative Orthology	response to freezing	AT1G12610
GO:0010628	ISO	PLAZA Integrative Orthology	positive regulation of gene expression	AT4G25480
GO:0019760	ISO	PLAZA Integrative Orthology	glucosinolate metabolic process	AT1G12610
GO:0045893	ISO	PLAZA Integrative Orthology	positive regulation of transcription, DNA-templated	AT4G25490
GO:0048510	ISO	PLAZA Integrative Orthology	regulation of timing of transition from vegetative to reproductive phase	AT1G12610
GO:0009408	ISO	PLAZA Integrative Orthology	response to heat	AT1G12610
GO:0009409	ISO	PLAZA Integrative Orthology	response to cold	AT4G25470
GO:0051510	ISO	PLAZA Integrative Orthology	regulation of unidimensional cell growth	AT1G12610
GO:0009631	ISO	PLAZA Integrative Orthology	cold acclimation	AT4G25470
GO:0009651	ISO	PLAZA Integrative Orthology	response to salt stress	AT1G12610
GO:0010371	ISO	PLAZA Integrative Orthology	regulation of gibberellin biosynthetic process	AT1G12610
GO:0006355	IEA	InterPro	regulation of transcription, DNA-templated

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005515	ISO	PLAZA Integrative Orthology	protein binding	AT4G25470
GO:0003677	IEA	InterPro	DNA binding
GO:0043565	ISO	PLAZA Integrative Orthology	sequence-specific DNA binding	AT1G12610
GO:0000987	ISO	PLAZA Integrative Orthology	cis-regulatory region sequence-specific DNA binding	AT4G25480
GO:0000976	ISO	PLAZA Integrative Orthology	transcription cis-regulatory region binding	AT1G12610
GO:0003700	IEA	InterPro	DNA-binding transcription factor activity

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR016177	DNA-binding domain superfamily
IPR001471	AP2/ERF domain
IPR036955	AP2/ERF domain superfamily

Mapman id	Description
15.5.7.2	RNA biosynthesis.transcriptional regulation.AP2/ERF transcription factor superfamily.transcription factor (DREB)
26.4.3.4.2	External stimuli response.temperature.cold response.ICE-CBF cold acclimation transcriptional cascade.transcription factor (CBF/DREB1)