Gene: AT5G08415

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G08415
  • Transcript Identifier AT5G08415.1
  • Gene Type Coding gene
  • Location Chr5 : 2710983-2713101 : negative

Gene Family Information

  • ID HOM05D002331
  • #Genes/#Species 291/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G08415.1
  • Alias LIP1,lipoyl synthase 1
  • uniprot Q8LEE8

Descriptions

  • Description Radical SAM superfamily protein
  • Computational description Radical SAM superfamily protein; FUNCTIONS IN: 4 iron, 4 sulfur cluster binding, lipoic acid synthase activity, iron-sulfur cluster binding, lipoate synthase activity, catalytic activity; INVOLVED IN: lipoic acid biosynthetic process, lipoate biosynthetic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Lipoate synthase (InterPro:IPR003698), Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Radical SAM (InterPro:IPR007197); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009107
IBA
IEA
GOA Databaselipoate biosynthetic process
GO:0009107
ISS
Gene Ontologylipoate biosynthetic process
GO:0009107
IEA
InterProlipoate biosynthetic process
GO:0009249
IEA
GOA Databaseprotein lipoylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0051536
IEA
GOA Databaseiron-sulfur cluster binding
GO:0051536
IEA
InterProiron-sulfur cluster binding
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0051539
IEA
GOA Database4 iron, 4 sulfur cluster binding
GO:0051539
IEA
InterPro4 iron, 4 sulfur cluster binding
GO:0016992
IBA
IEA
GOA Databaselipoate synthase activity
GO:0016992
IEA
InterProlipoate synthase activity
GO:0016740
IEA
GOA Databasetransferase activity
GO:0016783
IEA
GOA Databasesulfurtransferase activity
GO:0102553
IEA
Gene Ontologylipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)
GO:0102552
IEA
Gene Ontologylipoyl synthase activity (acting on glycine-cleavage complex H protein

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IBA
GOA Databasemitochondrion
GO:0009536
IEA
GOA Databaseplastid
GO:0009507
IEA
GOA Databasechloroplast

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR003698 Lipoyl synthase
IPR031691 Lipoyl synthase, N-terminal
IPR006638 Elp3/MiaB/NifB
IPR013785 Aldolase-type TIM barrel
IPR007197 Radical SAM
Mapman id Description
50.2.8 Enzyme classification.EC_2 transferases.EC_2.8 transferase transferring sulfur-containing group