Gene: AT5G07660

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G07660
  • Transcript Identifier AT5G07660.1
  • Gene Type Coding gene
  • Location Chr5 : 2422839-2429912 : positive

Gene Family Information

  • ID HOM05D004178
  • #Genes/#Species 169/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G07660.1
  • symbol SMC6A
  • uniprot Q9FLR5

Descriptions

  • Description structural maintenance of chromosomes 6A
  • Computational description structural maintenance of chromosomes 6A (SMC6A); FUNCTIONS IN: two-component sensor activity, ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation, response to X-ray, double-strand break repair via homologous recombination; LOCATED IN: chromosome, nucleus, membrane; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395), Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT5G61460.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IEA
InterProDNA repair
GO:0000724
IEA
GOA Databasedouble-strand break repair via homologous recombination
GO:0000724
IMP
IBA
Gene Ontologydouble-strand break repair via homologous recombination1 2
GO:0000724
IEA
InterProdouble-strand break repair via homologous recombination
GO:0051276
IEA
GOA Databasechromosome organization
GO:0051276
IEA
InterProchromosome organization
GO:0006310
IEA
GOA DatabaseDNA recombination
GO:0010165
IMP
Gene Ontologyresponse to X-ray1
GO:0007062
IMP
Gene Ontologysister chromatid cohesion1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016887
IEA
InterProATP hydrolysis activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0005515
IEA
InterProprotein binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0003684
IBA
Gene Ontologydamaged DNA binding2
GO:0003697
IBA
Gene Ontologysingle-stranded DNA binding2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030915
IEA
GOA DatabaseSmc5-Smc6 complex
GO:0030915
IBA
Gene OntologySmc5-Smc6 complex2
GO:0030915
IEA
InterProSmc5-Smc6 complex
GO:0005694
IEA
GOA Databasechromosome
GO:0005694
IEA
InterProchromosome
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM, IBA
Gene Ontologynucleus2
GO:0035861
IBA
Gene Ontologysite of double-strand break2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR003395 RecF/RecN/SMC, N-terminal
IPR036277 SMCs flexible hinge superfamily
IPR027132 Structural maintenance of chromosomes protein 6
Mapman id Description
14.3.6.1.2 DNA damage response.homologous recombination repair (HR).Smc5-Smc6 complex.NSE2-SMC5-SMC6 subcomplex.component SMC6