Gene: AT4G30870

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G30870
  • Transcript Identifier AT4G30870.1
  • Gene Type Coding gene
  • Location Chr4 : 15028586-15032461 : positive

Gene Family Information

  • ID HOM05D004944
  • #Genes/#Species 150/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G30870.1
  • symbol MUS81
  • Alias ATMUS81,ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81
  • full_name MMS AND UV SENSITIVE 81
  • uniprot Q5W9E7

Descriptions

  • Description Restriction endonuclease, type II-like superfamily protein
  • Computational description MMS AND UV SENSITIVE 81 (MUS81); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Restriction endonuclease, type II-like (InterPro:IPR011335); BEST Arabidopsis thaliana protein match is: Restriction endonuclease, type II-like superfamily protein (TAIR:AT5G39770.1); Has 631 Blast hits to 481 proteins in 192 species: Archae - 11; Bacteria - 4; Metazoa - 158; Fungi - 249; Plants - 48; Viruses - 0; Other Eukaryotes - 161 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IMP
Gene OntologyDNA repair1
GO:0006310
IEA
GOA DatabaseDNA recombination
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006974
IEP
Gene Ontologycellular response to DNA damage stimulus2
GO:0007049
IEA
GOA Databasecell cycle
GO:0051301
IEA
GOA Databasecell division
GO:0051321
IEA
GOA Databasemeiotic cell cycle
GO:0006302
IEA
GOA Databasedouble-strand break repair
GO:0006302
IEA
InterProdouble-strand break repair
GO:0000737
IEA
Gene OntologyDNA catabolic process, endonucleolytic
GO:0000737
IEA
InterProDNA catabolic process, endonucleolytic
GO:0000724
IMP
Gene Ontologydouble-strand break repair via homologous recombination3
GO:0006312
IMP
Gene Ontologymitotic recombination1
GO:0051026
IGI
Gene Ontologychiasma assembly4
GO:0000723
IMP
Gene Ontologytelomere maintenance5
GO:0007129
IGI
Gene Ontologyhomologous chromosome pairing at meiosis6
GO:0000712
IBA
Gene Ontologyresolution of meiotic recombination intermediates7
GO:0000727
IBA
Gene Ontologydouble-strand break repair via break-induced replication7
GO:0031573
IBA
Gene Ontologymitotic intra-S DNA damage checkpoint signaling7

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004518
IEA
GOA Databasenuclease activity
GO:0004518
IEA
InterPronuclease activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0004519
IEA
GOA Databaseendonuclease activity
GO:0004519
ISS
Gene Ontologyendonuclease activity1
GO:0008821
IEA
Gene Ontologycrossover junction endodeoxyribonuclease activity
GO:0008821
IEA
InterProcrossover junction endodeoxyribonuclease activity
GO:0048257
IBA
Gene Ontology3'-flap endonuclease activity7

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM, IBA
Gene Ontologynucleus7
GO:0005730
IEA
GOA Databasenucleolus
GO:0000794
IDA
Gene Ontologycondensed nuclear chromosome4
GO:0048476
IBA
Gene OntologyHolliday junction resolvase complex7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR006166 ERCC4 domain
IPR036388 Winged helix-like DNA-binding domain superfamily
IPR033309 Crossover junction endonuclease Mus81
IPR042530 EME1/EME2, C-terminal domain
IPR011335 Restriction endonuclease type II-like
Mapman id Description
13.3.5.5.2.1.1.1 Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic crossover.class II interference-insensitive crossover pathway.MUS81-dependent pathway.MUS81-EME1 Holliday junction cleavage heterodimer.component MUS81