Gene: AT2G30110
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT2G30110
- Transcript Identifier AT2G30110.1
- Gene Type Coding gene
- Location Chr2 : 12852632-12857369 : negative
Gene Family Information
- ID HOM05D001929
- #Genes/#Species 342/98
- Phylogenetic origin
- ID ORTHO05D002426
- #Genes/#Species 289/99
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT2G30110.1
- symbol UBA1
- Alias ATUBA1,ubiquitin-activating enzyme 1,MOS5,MODIFIER OF SNC1 5
- uniprot P93028
Descriptions
- Description ubiquitin-activating enzyme 1
- Computational description ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0016567 | IDA IBA IEA | Gene Ontology | protein ubiquitination | 1 2 |
GO:0006464 | IEA | GOA Database | cellular protein modification process | |
GO:0006464 | IEA | InterPro | cellular protein modification process | |
GO:0046686 | IEP | GOA Database | response to cadmium ion | |
GO:0032446 | IBA | Gene Ontology | protein modification by small protein conjugation | 2 |
GO:0006974 | IBA | Gene Ontology | cellular response to DNA damage stimulus | 2 |
GO:0006511 | IBA TAS | Gene Ontology | ubiquitin-dependent protein catabolic process | 2 3 |
GO:0051707 | IMP | Gene Ontology | response to other organism | 4 |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0008641 | IEA | GOA Database | ubiquitin-like modifier activating enzyme activity | |
GO:0008641 | IEA | InterPro | ubiquitin-like modifier activating enzyme activity | |
GO:0005524 | IEA | GOA Database | ATP binding | |
GO:0000166 | IEA | GOA Database | nucleotide binding | |
GO:0016874 | IEA | GOA Database | ligase activity | |
GO:0004839 | IEA | GOA Database | ubiquitin activating enzyme activity | |
GO:0004839 | IMP IBA | Gene Ontology | ubiquitin activating enzyme activity | 1 2 |
GO:0004842 | IDA | Gene Ontology | ubiquitin-protein transferase activity | 1 |
Cellular Component
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0009506 | IDA | GOA Database | plasmodesma | |
GO:0009506 | HDA | Gene Ontology | plasmodesma | 5 |
GO:0005829 | IDA | GOA Database | cytosol | |
GO:0005829 | HDA | Gene Ontology | cytosol | 6 |
GO:0005886 | IDA | GOA Database | plasma membrane | |
GO:0005634 | ISM, IBA | Gene Ontology | nucleus | 2 |
GO:0005737 | IBA | Gene Ontology | cytoplasm | 2 |
GO:0005777 | HDA | Gene Ontology | peroxisome | 7 |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR042063 | Ubiquitin-activating enzyme E1, SCCH domain |
IPR038252 | Ubiquitin-activating enzyme E1, C-terminal domain superfamily |
IPR042449 | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 |
IPR032420 | Ubiquitin-activating enzyme E1, four-helix bundle |
IPR035985 | Ubiquitin-activating enzyme |
IPR018965 | Ubiquitin-activating enzyme E1, C-terminal |
IPR000594 | THIF-type NAD/FAD binding fold |
IPR019572 | Ubiquitin-activating enzyme, SCCH domain |
IPR018075 | Ubiquitin-activating enzyme E1 |
IPR000011 | Ubiquitin/SUMO-activating enzyme E1 |
IPR032418 | Ubiquitin-activating enzyme E1, FCCH domain |
IPR042302 | Ubiquitin-activating enzyme E1, FCCH domain superfamily |
Mapman id | Description |
---|---|
19.2.2.1.2 | Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.ubiquitin conjugation (ubiquitylation).ubiquitin-activating E1 protein (UBA) |