Gene: AT2G20860

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G20860
  • Transcript Identifier AT2G20860.3
  • Gene Type Coding gene
  • Location Chr2 : 8979636-8980983 : positive

Gene Family Information

  • ID HOM05D002331
  • #Genes/#Species 291/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G20860.3
  • symbol LIP1
  • uniprot Q9ZWT1

Descriptions

  • Description lipoic acid synthase 1
  • Computational description LIPOIC ACID SYNTHASE 1 (LIP1); FUNCTIONS IN: lipoic acid synthase activity; INVOLVED IN: lipoic acid biosynthetic process, glycine catabolic process; LOCATED IN: mitochondrion, mitochondrial matrix; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Lipoate synthase (InterPro:IPR003698), Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Radical SAM (InterPro:IPR007197); BEST Arabidopsis thaliana protein match is: lipoic acid synthase family protein (TAIR:AT5G08415.1); Has 5683 Blast hits to 5683 proteins in 1186 species: Archae - 36; Bacteria - 2370; Metazoa - 113; Fungi - 91; Plants - 53; Viruses - 0; Other Eukaryotes - 3020 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009107
IEA
GOA Databaselipoate biosynthetic process
GO:0009107
IGI
IBA
TAS
Gene Ontologylipoate biosynthetic process1 2
GO:0009107
IEA
InterProlipoate biosynthetic process
GO:0009249
IEA
GOA Databaseprotein lipoylation
GO:0006546
TAS
Gene Ontologyglycine catabolic process1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016783
IEA
GOA Databasesulfurtransferase activity
GO:0051536
IEA
GOA Databaseiron-sulfur cluster binding
GO:0051536
IEA
InterProiron-sulfur cluster binding
GO:0051539
IEA
GOA Database4 iron, 4 sulfur cluster binding
GO:0051539
IEA
InterPro4 iron, 4 sulfur cluster binding
GO:0016992
IEA
GOA Databaselipoate synthase activity
GO:0016992
IGI
IBA
Gene Ontologylipoate synthase activity1 2
GO:0016992
IEA
InterProlipoate synthase activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0016740
IEA
GOA Databasetransferase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0102552
IEA
Gene Ontologylipoyl synthase activity (acting on glycine-cleavage complex H protein
GO:0102553
IEA
Gene Ontologylipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IEA
GOA Databasemitochondrion
GO:0005739
IDA
IBA
Gene Ontologymitochondrion1 2
GO:0005759
IDA
Gene Ontologymitochondrial matrix1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR013785 Aldolase-type TIM barrel
IPR003698 Lipoyl synthase
IPR007197 Radical SAM
IPR031691 Lipoyl synthase, N-terminal
IPR006638 Elp3/MiaB/NifB
Mapman id Description
7.15.1 Coenzyme metabolism.lipoic acid biosynthesis.lipoate synthase