Gene: AT1G74260

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G74260
  • Transcript Identifier AT1G74260.1
  • Gene Type Coding gene
  • Location Chr1 : 27923005-27927764 : negative

Gene Family Information

  • ID HOM05D003384
  • #Genes/#Species 202/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G74260.1
  • symbol PUR4
  • uniprot Q9M8D3

Descriptions

  • Description purine biosynthesis 4
  • Computational description purine biosynthesis 4 (PUR4); FUNCTIONS IN: phosphoribosylformylglycinamidine synthase activity, catalytic activity, ATP binding; INVOLVED IN: microgametogenesis, pollen development; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PurM, N-terminal-like (InterPro:IPR016188), Phosphoribosylformylglycinamidine synthase, eukaryote/proteobacteria (InterPro:IPR010073), AIR synthase related protein (InterPro:IPR000728), AIR synthase related protein, C-terminal (InterPro:IPR010918), Glutamine amidotransferase type 1 (InterPro:IPR017926); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006189
IEA
GOA Database'de novo' IMP biosynthetic process
GO:0006189
IEA
InterPro'de novo' IMP biosynthetic process
GO:0006541
IEA
GOA Databaseglutamine metabolic process
GO:0006164
IEA
GOA Databasepurine nucleotide biosynthetic process
GO:0009555
IMP
Gene Ontologypollen development1
GO:0055046
IMP
Gene Ontologymicrogametogenesis2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004642
IEA
GOA Databasephosphoribosylformylglycinamidine synthase activity
GO:0004642
TAS
Gene Ontologyphosphoribosylformylglycinamidine synthase activity2
GO:0004642
IEA
InterProphosphoribosylformylglycinamidine synthase activity
GO:0005524
IDA
IEA
GOA DatabaseATP binding
GO:0005524
HDA
Gene OntologyATP binding3
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016874
IEA
GOA Databaseligase activity
GO:0046872
IEA
GOA Databasemetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IEA
GOA Databasechloroplast
GO:0009507
IDA, HDA
ISM
Gene Ontologychloroplast2 4
GO:0009536
IEA
GOA Databaseplastid
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma5
GO:0005739
IEA
GOA Databasemitochondrion
GO:0005739
IDA, HDA
Gene Ontologymitochondrion2 3

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036676 PurM-like, C-terminal domain superfamily
IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily
IPR010918 PurM-like, C-terminal domain
IPR036921 PurM-like, N-terminal domain superfamily
IPR041609 Phosphoribosylformylglycinamidine synthase, linker domain
IPR010073 Phosphoribosylformylglycinamidine synthase PurL
IPR029062 Class I glutamine amidotransferase-like
IPR040707 Phosphoribosylformylglycinamidine synthase, N-terminal
Mapman id Description
6.1.1.4 Nucleotide metabolism.purines.ribonucleotide (RN) anabolism.formylglycinamidine RN synthase