Gene: AT1G29630
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G29630
- Transcript Identifier AT1G29630.2
- Gene Type Coding gene
- Location Chr1 : 10349587-10353538 : positive
Gene Family Information
- ID HOM05D002606
- #Genes/#Species 262/98
- Phylogenetic origin
- ID ORTHO05D003016
- #Genes/#Species 248/98
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT1G29630.2
- uniprot Q8L6Z7
Descriptions
- Description 5'-3' exonuclease family protein
- Computational description 5'-3' exonuclease family protein; FUNCTIONS IN: nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G18090.2); Has 2289 Blast hits to 1947 proteins in 363 species: Archae - 277; Bacteria - 0; Metazoa - 618; Fungi - 685; Plants - 238; Viruses - 12; Other Eukaryotes - 459 (source: NCBI BLink).
- Computational description 5'-3' exonuclease family protein; FUNCTIONS IN: DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G18090.2); Has 2407 Blast hits to 2171 proteins in 377 species: Archae - 277; Bacteria - 0; Metazoa - 635; Fungi - 677; Plants - 227; Viruses - 36; Other Eukaryotes - 555 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006281 | IEA | GOA Database | DNA repair | |
| GO:0006281 | IEA | InterPro | DNA repair | |
| GO:0006974 | IEA | GOA Database | cellular response to DNA damage stimulus | |
| GO:0090305 | IEA | GOA Database | nucleic acid phosphodiester bond hydrolysis |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0004527 | IEA | GOA Database | exonuclease activity | |
| GO:0003824 | IEA | GOA Database | catalytic activity | |
| GO:0003824 | IEA | InterPro | catalytic activity | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0046872 | IEA | InterPro | metal ion binding | |
| GO:0004518 | IEA | GOA Database | nuclease activity | |
| GO:0004518 | IEA | InterPro | nuclease activity | |
| GO:0035312 | IEA | Gene Ontology | 5'-3' exodeoxyribonuclease activity | |
| GO:0035312 | IEA | InterPro | 5'-3' exodeoxyribonuclease activity | |
| GO:0003677 | IEA | GOA Database | DNA binding | |
| GO:0003677 | IEA | InterPro | DNA binding | |
| GO:0016788 | IEA | GOA Database | hydrolase activity, acting on ester bonds | |
| GO:0004519 | IEA | GOA Database | endonuclease activity | |
| GO:0016787 | IEA | GOA Database | hydrolase activity | |
| GO:0017108 | IBA | Gene Ontology | 5'-flap endonuclease activity | 1 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005634 | IEA | GOA Database | nucleus | |
| GO:0005634 | ISM | Gene Ontology | nucleus |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR037315 | Exonuclease-1, H3TH domain |
| IPR006086 | XPG-I domain |
| IPR006084 | XPG/Rad2 endonuclease |
| IPR044752 | Exonuclease 1-like, PIN-like domain |
| IPR032641 | Exonuclease 1 |
| IPR008918 | Helix-hairpin-helix motif, class 2 |
| IPR029060 | PIN-like domain superfamily |
| IPR006085 | XPG, N-terminal |
| IPR036279 | 5'-3' exonuclease, C-terminal domain superfamily |
| Mapman id | Description |
|---|---|
| 14.3.4 | DNA damage response.homologous recombination repair (HR).exonuclease (EXO1) |