Gene: AT1G17745

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G17745
  • Transcript Identifier AT1G17745.1
  • Gene Type Coding gene
  • Location Chr1 : 6101157-6104979 : positive

Gene Family Information

  • ID HOM05D001181
  • #Genes/#Species 527/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G17745.1
  • symbol PGDH
  • Alias PGDH2,phosphoglycerate dehydrogenase 2
  • full_name 3-phosphoglycerate dehydrogenase
  • uniprot O04130

Descriptions

  • Description D-3-phosphoglycerate dehydrogenase
  • Computational description 3-phosphoglycerate dehydrogenase (PGDH); FUNCTIONS IN: phosphoglycerate dehydrogenase activity, protein binding; INVOLVED IN: L-serine biosynthetic process; LOCATED IN: cytosol, nucleus, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: D-3-phosphoglycerate dehydrogenase (InterPro:IPR006236), D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (InterPro:IPR006139), D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (InterPro:IPR006140), D-3-phosphogylcerate Dehydrogenase (InterPro:IPR015508), Amino acid-binding ACT (InterPro:IPR002912), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: D-3-phosphoglycerate dehydrogenase (TAIR:AT4G34200.1); Has 30450 Blast hits to 30444 proteins in 2726 species: Archae - 473; Bacteria - 18179; Metazoa - 739; Fungi - 1175; Plants - 595; Viruses - 5; Other Eukaryotes - 9284 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006564
IEA
GOA DatabaseL-serine biosynthetic process
GO:0006564
TAS
Gene OntologyL-serine biosynthetic process1
GO:0006564
IEA
InterProL-serine biosynthetic process
GO:0008652
IEA
GOA Databasecellular amino acid biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016616
IEA
GOA Databaseoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016616
IEA
InterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004617
IEA
GOA Databasephosphoglycerate dehydrogenase activity
GO:0004617
IGI
IBA
Gene Ontologyphosphoglycerate dehydrogenase activity1 2
GO:0004617
IEA
InterProphosphoglycerate dehydrogenase activity
GO:0051287
IEA
Gene OntologyNAD binding
GO:0051287
IEA
InterProNAD binding
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0005515
IPI
Gene Ontologyprotein binding3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IEA
GOA Databasechloroplast
GO:0009507
IDA, HDA
ISM
Gene Ontologychloroplast1 4
GO:0009536
IEA
GOA Databaseplastid
GO:0005634
IDA
GOA Databasenucleus
GO:0005634
HDA
Gene Ontologynucleus5
GO:0005829
IDA
GOA Databasecytosol
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
IBA
Gene Ontologychloroplast stroma2 6

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
IPR002912 ACT domain
IPR029009 Allosteric substrate binding domain superfamily
IPR036291 NAD(P)-binding domain superfamily
IPR006236 D-3-phosphoglycerate dehydrogenase
IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Mapman id Description
4.1.4.1.1 Amino acid metabolism.biosynthesis.serine family.non-photorespiratory serine.phosphoglycerate dehydrogenase