InterPro domain: IPR006140

General Information

  • Identifier IPR006140
  • Description D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
  • Number of genes 1619
  • Gene duplication stats Loading...
  • Associated GO terms GO:0051287  

Abstract

A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to bespecific for the D-isomer of their substrate have been shown to be functionally and structurally related. All contain a glycine-rich region located in the central section of these enzymes, this region corresponds to the NAD-binding domain. This domain is inserted into the catalytic domain. The catalytic domain is described in ( IPR006139 ).

Species distribution

Gene table