Gene: AT1G04410

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G04410
  • Transcript Identifier AT1G04410.1
  • Gene Type Coding gene
  • Location Chr1 : 1189418-1191267 : negative

Gene Family Information

  • ID HOM05D001289
  • #Genes/#Species 486/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G04410.1
  • symbol c-NAD-MDH1
  • full_name cytosolic-NAD-dependent malate dehydrogenase 1
  • uniprot Q593N9

Descriptions

  • Description Lactate/malate dehydrogenase family protein
  • Computational description Lactate/malate dehydrogenase family protein; FUNCTIONS IN: in 6 functions; INVOLVED IN: response to cadmium ion, response to zinc ion, response to salt stress; LOCATED IN: in 7 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Malate dehydrogenase, NAD-dependent, cytosolic (InterPro:IPR011274), Lactate/malate dehydrogenase, N-terminal (InterPro:IPR001236), Malate dehydrogenase, NAD/NADP (InterPro:IPR010945), Lactate/malate dehydrogenase, C-terminal (InterPro:IPR022383), NAD(P)-binding domain (InterPro:IPR016040), L-lactate/malate dehydrogenase (InterPro:IPR001557), Malate dehydrogenase, active site (InterPro:IPR001252), Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (InterPro:IPR015955); BEST Arabidopsis thaliana protein match is: Lactate/malate dehydrogenase family protein (TAIR:AT5G43330.1); Has 11998 Blast hits to 11997 proteins in 3022 species: Archae - 169; Bacteria - 7171; Metazoa - 1456; Fungi - 287; Plants - 683; Viruses - 0; Other Eukaryotes - 2232 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006099
IBA
Gene Ontologytricarboxylic acid cycle1
GO:0006108
IEA
GOA Databasemalate metabolic process
GO:0006108
IBA
Gene Ontologymalate metabolic process1
GO:0006108
IEA
InterPromalate metabolic process
GO:0019752
IEA
InterProcarboxylic acid metabolic process
GO:0005975
IEA
Gene Ontologycarbohydrate metabolic process
GO:0005975
IEA
InterProcarbohydrate metabolic process
GO:0006734
IBA
Gene OntologyNADH metabolic process1
GO:0006107
IBA
Gene Ontologyoxaloacetate metabolic process1
GO:0010043
IEP
Gene Ontologyresponse to zinc ion2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016615
IEA
GOA Databasemalate dehydrogenase activity
GO:0016615
IEA
InterPromalate dehydrogenase activity
GO:0030060
IBA
Gene OntologyL-malate dehydrogenase activity1
GO:0030060
IEA
InterProL-malate dehydrogenase activity
GO:0016616
IEA
InterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0003824
IEA
InterProcatalytic activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0003729
IDA
Gene OntologymRNA binding3
GO:0005515
IPI
Gene Ontologyprotein binding4

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISM
Gene Ontologycytoplasm
GO:0005576
HDA
Gene Ontologyextracellular region5
GO:0005829
HDA
RCA
Gene Ontologycytosol6 7
GO:0005794
RCA
Gene OntologyGolgi apparatus8
GO:0009506
HDA
Gene Ontologyplasmodesma9
GO:0048046
HDA
Gene Ontologyapoplast10
GO:0009507
HDA
Gene Ontologychloroplast11
GO:0005886
HDA
Gene Ontologyplasma membrane12
GO:0009570
HDA
Gene Ontologychloroplast stroma13
GO:0000325
HDA
Gene Ontologyplant-type vacuole14
GO:0005634
HDA
Gene Ontologynucleus15

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001236 Lactate/malate dehydrogenase, N-terminal
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR001557 L-lactate/malate dehydrogenase
IPR011274 Malate dehydrogenase, NAD-dependent, cytosolic
IPR036291 NAD(P)-binding domain superfamily
IPR010945 Malate dehydrogenase, type 2
IPR022383 Lactate/malate dehydrogenase, C-terminal
Mapman id Description
1.4.2 Photosynthesis.CAM/C4 photosynthesis.NAD-dependent malate dehydrogenase
5.1.1.3 Lipid metabolism.fatty acid biosynthesis.citrate shuttle.cytosolic NAD-dependent malate dehydrogenase