Gene: AT1G03190
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G03190
- Transcript Identifier AT1G03190.1
- Gene Type Coding gene
- Location Chr1 : 775822-779863 : positive
Gene Family Information
- ID HOM05D005387
- #Genes/#Species 141/97
- Phylogenetic origin
- ID ORTHO05D006711
- #Genes/#Species 139/97
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT1G03190.1
- symbol UVH6
- Alias ATXPD,ARABIDOPSIS THALIANA XERODERMA PIGMENTOSUM GROUP D
- full_name ULTRAVIOLET HYPERSENSITIVE 6
- uniprot Q8W4M7
Descriptions
- Description RAD3-like DNA-binding helicase protein
- Computational description ULTRAVIOLET HYPERSENSITIVE 6 (UVH6); FUNCTIONS IN: in 6 functions; INVOLVED IN: DNA repair, response to UV, response to heat; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type (InterPro:IPR014013), Xeroderma pigmentosum group D protein (InterPro:IPR001945), Helicase-like, DEXD box c2 type (InterPro:IPR006554), Helicase, ATP-dependent, c2 type (InterPro:IPR006555), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD2 (InterPro:IPR010614), DNA helicase (DNA repair), Rad3 type (InterPro:IPR013020), Protein of unknown function DUF1227 (InterPro:IPR010643); BEST Arabidopsis thaliana protein match is: RAD3-like DNA-binding helicase protein (TAIR:AT1G20720.1); Has 3290 Blast hits to 2576 proteins in 779 species: Archae - 308; Bacteria - 1186; Metazoa - 653; Fungi - 359; Plants - 198; Viruses - 2; Other Eukaryotes - 584 (source: NCBI BLink).
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Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006139 | IEA | GOA Database | nucleobase-containing compound metabolic process | |
| GO:0006139 | IEA | InterPro | nucleobase-containing compound metabolic process | |
| GO:0006289 | IEA | GOA Database | nucleotide-excision repair | |
| GO:0006289 | IEA | InterPro | nucleotide-excision repair | |
| GO:0016070 | ISO | PLAZA Integrative Orthology | RNA metabolic process | Solyc06g008970.4 |
| GO:0006281 | IEA | GOA Database | DNA repair | |
| GO:0006281 | IMP | Gene Ontology | DNA repair | 1 |
| GO:0009408 | IMP | Gene Ontology | response to heat | 2 |
| GO:0009411 | IMP IBA | Gene Ontology | response to UV | 3 4 |
| GO:0006366 | IBA | Gene Ontology | transcription by RNA polymerase II | 4 |
| GO:0033683 | IBA | Gene Ontology | nucleotide-excision repair, DNA incision | 4 |
| GO:0045951 | IBA | Gene Ontology | positive regulation of mitotic recombination | 4 |
| GO:0000717 | IBA | Gene Ontology | nucleotide-excision repair, DNA duplex unwinding | 4 |
| GO:0006979 | IBA | Gene Ontology | response to oxidative stress | 4 |
| GO:0006974 | IEA | GOA Database | cellular response to DNA damage stimulus |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0016818 | IEA | GOA Database | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | |
| GO:0016818 | IEA | InterPro | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | |
| GO:0003677 | IEA | GOA Database | DNA binding | |
| GO:0003677 | IEA | InterPro | DNA binding | |
| GO:0016787 | IEA | GOA Database | hydrolase activity | |
| GO:0000166 | IEA | GOA Database | nucleotide binding | |
| GO:0004386 | IEA | GOA Database | helicase activity | |
| GO:0004386 | IEA | InterPro | helicase activity | |
| GO:0005524 | IEA | GOA Database | ATP binding | |
| GO:0005524 | IEA | InterPro | ATP binding | |
| GO:0003676 | IEA | GOA Database | nucleic acid binding | |
| GO:0003676 | IEA | InterPro | nucleic acid binding | |
| GO:0003678 | IEA | GOA Database | DNA helicase activity | |
| GO:0003678 | IBA | Gene Ontology | DNA helicase activity | 4 |
| GO:0003678 | IEA | InterPro | DNA helicase activity | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0003724 | ISO | PLAZA Integrative Orthology | RNA helicase activity | Solyc06g008970.4 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 5 |
| GO:0003684 | IBA | Gene Ontology | damaged DNA binding | 4 |
| GO:0051539 | IEA | GOA Database | 4 iron, 4 sulfur cluster binding | |
| GO:0051536 | IEA | GOA Database | iron-sulfur cluster binding |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005634 | IEA | GOA Database | nucleus | |
| GO:0005634 | ISM, IBA | Gene Ontology | nucleus | 4 |
| GO:0005634 | IEA | InterPro | nucleus |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR006554 | Helicase-like, DEXD box c2 type |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR006555 | ATP-dependent helicase, C-terminal |
| IPR010614 | DEAD2 |
| IPR001945 | RAD3/XPD family |
| IPR010643 | Helical and beta-bridge domain |
| IPR045028 | Helicase superfamily 1/2, DinG/Rad3-like |
| IPR013020 | ATP-dependent helicase Rad3/Chl1-like |
| Mapman id | Description |
|---|---|
| 14.6.3.2.1 | DNA damage response.nucleotide excision repair (NER).multi-functional TFIIh complex.core module.subunit XPD |
| 15.3.3.5.1.1 | RNA biosynthesis.RNA polymerase II-dependent transcription.transcription initiation.TFIIh basal transcription factor complex.core module.component RAD3/XPD |