Gene: AT1G03090
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G03090
- Transcript Identifier AT1G03090.2
- Gene Type Coding gene
- Location Chr1 : 739715-743819 : positive
Gene Family Information
- ID HOM05D002240
- #Genes/#Species 301/99
- Phylogenetic origin
- ID ORTHO05D002453
- #Genes/#Species 286/99
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT1G03090.2
- symbol MCCA
- uniprot Q42523
Descriptions
- Description methylcrotonyl-CoA carboxylase alpha chain
- Computational description MCCA; FUNCTIONS IN: cobalt ion binding, methylcrotonoyl-CoA carboxylase activity; INVOLVED IN: leucine catabolic process; LOCATED IN: mitochondrion, cytosolic ribosome; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Single hybrid motif (InterPro:IPR011053), Biotin/lipoyl attachment (InterPro:IPR000089), Carbamoyl phosphate synthase, large subunit, N-terminal (InterPro:IPR005481), Carbamoyl phosphate synthetase, large subunit, ATP-binding (InterPro:IPR005479), PreATP-grasp-like fold (InterPro:IPR016185), Biotin-binding site (InterPro:IPR001882), Biotin carboxylation domain (InterPro:IPR011764), Biotin carboxylase, C-terminal (InterPro:IPR005482), ATP-grasp fold (InterPro:IPR011761), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Rudiment single hybrid motif (InterPro:IPR011054), Pre-ATP-grasp fold (InterPro:IPR013817); BEST Arabidopsis thaliana protein match is: acetyl Co-enzyme a carboxylase biotin carboxylase subunit (TAIR:AT5G35360.1); Has 35200 Blast hits to 30603 proteins in 3073 species: Archae - 603; Bacteria - 22615; Metazoa - 922; Fungi - 892; Plants - 784; Viruses - 0; Other Eukaryotes - 9384 (source: NCBI BLink).
- Computational description MCCA; FUNCTIONS IN: cobalt ion binding, methylcrotonoyl-CoA carboxylase activity; INVOLVED IN: leucine catabolic process; LOCATED IN: mitochondrion, cytosolic ribosome; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Single hybrid motif (InterPro:IPR011053), Biotin/lipoyl attachment (InterPro:IPR000089), Carbamoyl phosphate synthase, large subunit, N-terminal (InterPro:IPR005481), Carbamoyl phosphate synthetase, large subunit, ATP-binding (InterPro:IPR005479), PreATP-grasp-like fold (InterPro:IPR016185), Biotin-binding site (InterPro:IPR001882), Biotin carboxylation domain (InterPro:IPR011764), Biotin carboxylase, C-terminal (InterPro:IPR005482), ATP-grasp fold (InterPro:IPR011761), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Rudiment single hybrid motif (InterPro:IPR011054), Pre-ATP-grasp fold (InterPro:IPR013817); BEST Arabidopsis thaliana protein match is: acetyl Co-enzyme a carboxylase biotin carboxylase subunit (TAIR:AT5G35360.1); Has 41492 Blast hits to 34824 proteins in 3674 species: Archae - 718; Bacteria - 26555; Metazoa - 1797; Fungi - 1117; Plants - 802; Viruses - 0; Other Eukaryotes - 10503 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006552 | IDA IEA | Gene Ontology | leucine catabolic process | 1 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005524 | IEA | GOA Database | ATP binding | |
| GO:0005524 | IEA | InterPro | ATP binding | |
| GO:0016421 | IBA | GOA Database | CoA carboxylase activity | |
| GO:0004485 | IBA IEA | GOA Database | methylcrotonoyl-CoA carboxylase activity | |
| GO:0004485 | IDA | Gene Ontology | methylcrotonoyl-CoA carboxylase activity | 1 |
| GO:0000166 | IEA | GOA Database | nucleotide binding | |
| GO:0016874 | IEA | GOA Database | ligase activity | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0050897 | IDA | GOA Database | cobalt ion binding | |
| GO:0050897 | HDA | Gene Ontology | cobalt ion binding | 2 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005759 | IEA | GOA Database | mitochondrial matrix | |
| GO:0005739 | IEA | GOA Database | mitochondrion | |
| GO:0005739 | IDA, HDA ISM, IBA | Gene Ontology | mitochondrion | 1 3 4 |
| GO:0022626 | IDA | GOA Database | cytosolic ribosome | |
| GO:0022626 | HDA | Gene Ontology | cytosolic ribosome | 5 |
| GO:0005576 | HDA | Gene Ontology | extracellular region | 6 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR005482 | Biotin carboxylase, C-terminal |
| IPR016185 | Pre-ATP-grasp domain superfamily |
| IPR011054 | Rudiment single hybrid motif |
| IPR000089 | Biotin/lipoyl attachment |
| IPR005481 | Biotin carboxylase-like, N-terminal domain |
| IPR011053 | Single hybrid motif |
| IPR005479 | Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain |
| Mapman id | Description |
|---|---|
| 4.2.7.5.1.1 | Amino acid metabolism.degradation.branched-chain amino acid.leucine.methylcrotonoyl-CoA carboxylase heterodimer.subunit alpha |