Interactive Phylogenetics Module

Contact Settings

If more than 50 genes/sequences are provided as input, then the associated running time can take some time.
Therefore it is advisable to provide an email-address in case you are running the Interactive Phylogenetics Module with more than 50 genes.
After processing you will be send an email with a link to the created phylogenetic tree.

Data Settings

Reference genes from current instance

The selection modi are exclusive: please choose either Gene selection or Species selection.

Include Gene ID Species Homologous gene family Orthologous gene family E-value Bitscore Alignment Length Identity Percentage
TPR.G26652 Trifolium pratense HOM05D003302 ORTHO05D003785 4.4e-147 524.6 272 100.0
Psat1g190600 Pisum sativum HOM05D003302 ORTHO05D003785 1.0e-103 380.6 217 88.5
Ca_00544_v3 Cicer arietinum L. HOM05D003302 ORTHO05D003785 7.4e-102 374.4 217 87.6
arahy.Tifrunner.gnm1.ann1.JNH5N4 Arachis hypogaea HOM05D003302 ORTHO05D003785 6.3e-101 371.3 217 85.7
arahy.Tifrunner.gnm1.ann1.VBQQ6F Arachis hypogaea HOM05D003302 ORTHO05D003785 1.1e-100 370.5 217 85.3
VMungo0540G2182 Vigna mungo HOM05D003302 ORTHO05D003785 3.1e-100 369.0 217 85.7
Lalb_Chr15g0086841 Lupinus albus HOM05D003302 ORTHO05D003785 5.3e-100 368.2 217 85.3
Glyma.15G094350 Glycine max HOM05D003302 ORTHO05D003785 2.0e-99 366.3 208 86.5
COL.COLO4_29330 Corchorus olitorius HOM05D003302 ORTHO05D003785 9.4e-97 357.5 217 82.0
Gohir.D11G331550 Gossypium hirsutum HOM05D003302 ORTHO05D003785 1.2e-96 357.1 208 84.1
Hma1.2p1_0053F.1_g030960 Hydrangea macrophylla HOM05D003302 ORTHO05D003785 2.1e-96 356.3 208 83.7
Thecc.05G173100 Theobroma cacao HOM05D003302 ORTHO05D003785 4.7e-96 355.1 208 84.1
TWI38G0102 Tripterygium wilfordii HOM05D003302 ORTHO05D003785 4.7e-96 355.1 217 81.1
Duzib128G1415 Durio zibethinus HOM05D003302 ORTHO05D003785 6.1e-96 354.8 216 81.9
QL10p038886 Quercus lobata HOM05D003302 ORTHO05D003785 7.9e-96 354.4 217 80.6
Cfa000950 Carpinus fangiana HOM05D003302 ORTHO05D003785 1.0e-95 354.0 217 80.6
Haze_05590 Corylus avellana HOM05D003302 ORTHO05D003785 1.0e-95 354.0 217 80.6
CiPaw.09G124000 Carya illinoinensis HOM05D003302 ORTHO05D003785 1.8e-95 353.2 217 80.6
CANSAT35G0225 Cannabis sativa HOM05D003302 ORTHO05D003785 3.0e-95 352.4 208 82.7
Gohir.A11G314450 Gossypium hirsutum HOM05D003302 ORTHO05D003785 5.1e-95 351.7 208 83.2
MD05G1284200 Malus domestica HOM05D003302 ORTHO05D003785 5.1e-95 351.7 217 81.1
Cpa.g.sc166.10 Carica papaya HOM05D003302 ORTHO05D003785 8.8e-95 350.9 217 80.6
FvH4_3g05620 Fragaria vesca HOM05D003302 ORTHO05D003785 2.0e-94 349.7 217 79.7
FAN11G3285 Fragaria x ananassa HOM05D003302 ORTHO05D003785 2.0e-94 349.7 217 79.7
FAN21G1953 Fragaria x ananassa HOM05D003302 ORTHO05D003785 2.0e-94 349.7 217 79.7
Sabra04G0085500 Salix brachista HOM05D003302 ORTHO05D003785 2.0e-94 349.7 217 80.2
RcHm_v2.0_Chr5g0014061 Rosa chinensis HOM05D003302 ORTHO05D003785 5.7e-94 348.2 217 79.3
Potri.004G132450 Populus trichocarpa HOM05D003302 ORTHO05D003785 7.4e-94 347.8 217 79.7
Solyc01g112025.1 Solanum lycopersicum HOM05D003302 ORTHO05D003785 7.4e-94 347.8 208 82.2
Sopen01g054090 Solanum pennellii HOM05D003302 ORTHO05D003785 7.4e-94 347.8 208 82.2
Aa31LG6G5650 Aethionema arabicum HOM05D003302 ORTHO05D003785 9.7e-94 347.4 217 78.3
ClCG03G006880 Citrullus lanatus HOM05D003302 ORTHO05D003785 9.7e-94 347.4 217 80.2
Oeu034153.1 Olea europaea HOM05D003302 ORTHO05D003785 9.7e-94 347.4 217 80.2
Dinv30741 Davidia involucrata HOM05D003302 ORTHO05D003785 1.7e-93 346.7 216 80.1
Nitab4.5_0011942g0010 Nicotiana tabacum HOM05D003302 ORTHO05D003785 1.7e-93 346.7 208 81.2
PGSC0003DMG400018655 Solanum tuberosum HOM05D003302 ORTHO05D003785 2.2e-93 346.3 208 82.2
Lj1P1187T27 Lonicera japonica HOM05D003302 ORTHO05D003785 2.8e-93 345.9 217 78.3
MELO3C002733.2 Cucumis melo HOM05D003302 ORTHO05D003785 3.7e-93 345.5 217 79.7
Nn3g20766 Nelumbo nucifera HOM05D003302 ORTHO05D003785 3.7e-93 345.5 208 80.3
unitig_32.g11443 Utricularia gibba HOM05D003302 ORTHO05D003785 3.7e-93 345.5 217 78.8
Nitab4.5_0000165g0160 Nicotiana tabacum HOM05D003302 ORTHO05D003785 4.8e-93 345.1 208 80.8
PGR083G1399 Punica granatum HOM05D003302 ORTHO05D003785 4.8e-93 345.1 208 80.8
CAN.G1235.21 Capsicum annuum HOM05D003302 ORTHO05D003785 6.3e-93 344.7 208 81.7
DCAR_003918 Daucus carota HOM05D003302 ORTHO05D003785 8.2e-93 344.4 217 78.8
Aqoxy1G01714 Aquilegia oxysepala HOM05D003302 ORTHO05D003785 1.4e-92 343.6 217 77.4
CsaV3_1G032460 Cucumis sativus L. HOM05D003302 ORTHO05D003785 1.4e-92 343.6 217 79.3
Manes.17G069108 Manihot esculenta HOM05D003302 ORTHO05D003785 1.4e-92 343.6 217 79.3
Sp1g25890 Schrenkiella parvula HOM05D003302 ORTHO05D003785 2.4e-92 342.8 208 79.8
AL1G43900 Arabidopsis lyrata HOM05D003302 ORTHO05D003785 3.1e-92 342.4 217 78.3
A09p36490 Brassica napus HOM05D003302 ORTHO05D003785 3.1e-92 342.4 217 77.0
BraA09t39172Z Brassica rapa HOM05D003302 ORTHO05D003785 3.1e-92 342.4 217 77.0
AT1G30010 Arabidopsis thaliana HOM05D003302 ORTHO05D003785 4.1e-92 342.0 217 77.9
CARHR029380 Cardamine hirsuta HOM05D003302 ORTHO05D003785 7.0e-92 341.3 217 77.9
Atru.chr10.1237 Acer truncatum HOM05D003302 ORTHO05D003785 9.1e-92 340.9 217 77.9
Os12g0407300 Oryza sativa ssp. japonica HOM05D003302 ORTHO05D003785 9.1e-92 340.9 208 79.8
BcaC05g27013 Brassica carinata HOM05D003302 ORTHO05D003785 1.6e-91 340.1 217 76.5
C05p28800 Brassica napus HOM05D003302 ORTHO05D003785 1.6e-91 340.1 217 76.5
BolC5t31597H Brassica oleracea HOM05D003302 ORTHO05D003785 1.6e-91 340.1 217 76.5
Sc05g0006220 Simmondsia chinensis HOM05D003302 ORTHO05D003785 4.5e-91 338.6 217 77.4
Zm00001eb006520 Zea mays HOM05D003302 ORTHO05D003785 4.5e-91 338.6 208 79.3
TAR629G3501 Trochodendron aralioides HOM05D003302 ORTHO05D003785 1.0e-90 337.4 208 79.8
MBI07_g26352_MAGBIO Magnolia biondii HOM05D003302 ORTHO05D003785 8.5e-90 334.3 208 77.4
THA.LOC104820647 Tarenaya hassleriana HOM05D003302 ORTHO05D003785 2.5e-89 332.8 217 76.5
HPP92_002850 Vanilla planifolia HOM05D003302 ORTHO05D003785 2.5e-89 332.8 208 77.4
CDE11G0149 Ceratophyllum demersum HOM05D003302 ORTHO05D003785 3.2e-89 332.4 208 76.0
Actinidia19525 Actinidia chinensis HOM05D003302 ORTHO05D003785 9.4e-89 330.9 217 76.0
vmacro03962 Vaccinium macrocarpon HOM05D003302 ORTHO05D003785 6.7e-87 324.7 208 76.9
ATR0064G047 Amborella trichopoda HOM05D003302 ORTHO05D003785 1.5e-86 323.6 208 75.5
PSO675G7265 Papaver somniferum HOM05D003302 ORTHO05D003785 9.7e-86 320.9 208 75.0
PSO541G5669 Papaver somniferum HOM05D003302 ORTHO05D003785 8.2e-85 317.8 208 74.5
SHI24871 Sapria himalayana HOM05D003302 ORTHO05D003785 8.2e-85 317.8 217 71.4
Rhsim13G0194800 Rhododendron simsii HOM05D003302 ORTHO05D003785 3.1e-84 315.8 208 75.0
AUR62002753 Chenopodium quinoa HOM05D003302 ORTHO05D003785 4.2e-81 305.4 217 69.1
AUR62030203 Chenopodium quinoa HOM05D003302 ORTHO05D003785 9.4e-81 304.3 217 69.1
EL10Ac4g07785 Beta vulgaris HOM05D003302 ORTHO05D003785 3.0e-79 299.3 217 67.7
Ah.09g232620 Amaranthus hybridus HOM05D003302 ORTHO05D003785 5.2e-79 298.5 216 68.1
HanXRQChr15g0486511 Helianthus annuus HOM05D003302 ORTHO05D003785 1.2e-78 297.4 217 65.0
SGA_v2.0_scaffold1G00170 Striga asiatica HOM05D003302 ORTHO05D003785 2.2e-77 293.1 217 71.0
ATR1091G061 Amborella trichopoda HOM05D003302 ORTHO05D003785 1.1e-76 290.8 208 70.2
ECA232G0620 Erigeron canadensis HOM05D003302 ORTHO05D003785 1.4e-76 290.4 217 64.5
Lsat_1_v5_gn_8_116740 Lactuca sativa HOM05D003302 ORTHO05D003785 1.6e-75 287.0 217 63.1
ATR0827G173 Amborella trichopoda HOM05D003302 ORTHO05D003785 1.9e-73 280.0 217 62.7
Aqoxy3G02548 Aquilegia oxysepala HOM05D003302 ORTHO05D003785 9.4e-73 277.7 217 60.8
Os10g0567500 Oryza sativa ssp. japonica HOM05D003302 ORTHO05D003785 2.1e-72 276.6 217 61.8
Zm00001eb004560 Zea mays HOM05D003302 ORTHO05D003785 2.7e-72 276.2 217 61.3
SEGI_25417 Sequoiadendron giganteum HOM05D003302 ORTHO05D003785 4.7e-72 275.4 217 60.8
HPP92_007162 Vanilla planifolia HOM05D003302 ORTHO05D003785 4.7e-72 275.4 217 59.4
SEGI_34960 Sequoiadendron giganteum HOM05D003302 ORTHO05D003785 6.1e-72 275.0 217 62.7
Zm00001eb210180 Zea mays HOM05D003302 ORTHO05D003785 8.0e-72 274.6 217 60.8
arahy.Tifrunner.gnm1.ann1.HY98G0 Arachis hypogaea HOM05D003302 ORTHO05D003785 1.8e-71 273.5 217 59.9
arahy.Tifrunner.gnm1.ann1.K481AV Arachis hypogaea HOM05D003302 ORTHO05D003785 1.8e-71 273.5 217 59.9
CANSAT11G1544 Cannabis sativa HOM05D003302 ORTHO05D003785 1.8e-71 273.5 217 60.4
Duzib084G0162 Durio zibethinus HOM05D003302 ORTHO05D003785 2.3e-71 273.1 217 59.0
Oeu037876.2 Olea europaea HOM05D003302 ORTHO05D003785 2.3e-71 273.1 217 59.4
Lalb_Chr18g0057931 Lupinus albus HOM05D003302 ORTHO05D003785 3.0e-71 272.7 217 59.4
FAN08G3359 Fragaria x ananassa HOM05D003302 ORTHO05D003785 4.0e-71 272.3 217 59.9
FAN13G0755 Fragaria x ananassa HOM05D003302 ORTHO05D003785 4.0e-71 272.3 217 59.9
FAN18G0007 Fragaria x ananassa HOM05D003302 ORTHO05D003785 4.0e-71 272.3 217 59.9
Nn1g00641 Nelumbo nucifera HOM05D003302 ORTHO05D003785 4.0e-71 272.3 217 59.9
Phvul.006G128900 Phaseolus vulgaris HOM05D003302 ORTHO05D003785 4.0e-71 272.3 208 60.6
RcHm_v2.0_Chr7g0208021 Rosa chinensis HOM05D003302 ORTHO05D003785 4.0e-71 272.3 217 59.9
Prupe.5G048500 Prunus persica HOM05D003302 ORTHO05D003785 5.2e-71 271.9 217 59.4
TWI60G1391 Tripterygium wilfordii HOM05D003302 ORTHO05D003785 5.2e-71 271.9 217 59.0
VMungo0540G1460 Vigna mungo HOM05D003302 ORTHO05D003785 5.2e-71 271.9 208 60.6
QL12p007349 Quercus lobata HOM05D003302 ORTHO05D003785 8.8e-71 271.2 208 60.1
Thecc.03G235300 Theobroma cacao HOM05D003302 ORTHO05D003785 8.8e-71 271.2 217 59.0
TAR375G0955 Trochodendron aralioides HOM05D003302 ORTHO05D003785 8.8e-71 271.2 217 59.4
EL10Ac8g19691 Beta vulgaris HOM05D003302 ORTHO05D003785 1.2e-70 270.8 202 66.3
Glyma.09G023300 Glycine max HOM05D003302 ORTHO05D003785 1.2e-70 270.8 208 60.1
Lj8P288T36 Lonicera japonica HOM05D003302 ORTHO05D003785 1.2e-70 270.8 217 58.5
Ca_00809_v3 Cicer arietinum L. HOM05D003302 ORTHO05D003785 1.5e-70 270.4 208 60.6
FvH4_5g21000 Fragaria vesca HOM05D003302 ORTHO05D003785 1.5e-70 270.4 217 59.4
Glyma.15G129400 Glycine max HOM05D003302 ORTHO05D003785 1.5e-70 270.4 208 60.1
PGR142G3064 Punica granatum HOM05D003302 ORTHO05D003785 1.5e-70 270.4 208 60.1
Gohir.A03G002901 Gossypium hirsutum HOM05D003302 ORTHO05D003785 2.0e-70 270.0 208 60.1
Gohir.D03G169466 Gossypium hirsutum HOM05D003302 ORTHO05D003785 2.0e-70 270.0 208 60.1
MSTRG.1965 Avicennia marina HOM05D003302 ORTHO05D003785 2.6e-70 269.6 208 59.6
Cpa.g.sc29.6 Carica papaya HOM05D003302 ORTHO05D003785 2.6e-70 269.6 208 60.1
Manes.15G171966 Manihot esculenta HOM05D003302 ORTHO05D003785 2.6e-70 269.6 217 58.5
unitig_62.g23447 Utricularia gibba HOM05D003302 ORTHO05D003785 2.6e-70 269.6 217 58.1
Sed0026531 Sechium edule HOM05D003302 ORTHO05D003785 3.4e-70 269.2 217 59.0
COL.COLO4_17129 Corchorus olitorius HOM05D003302 ORTHO05D003785 4.4e-70 268.9 217 59.0
Potri.001G147801 Populus trichocarpa HOM05D003302 ORTHO05D003785 4.4e-70 268.9 217 57.6
ClCG09G012410 Citrullus lanatus HOM05D003302 ORTHO05D003785 5.7e-70 268.5 217 59.0
CsaV3_3G049580 Cucumis sativus L. HOM05D003302 ORTHO05D003785 7.5e-70 268.1 217 59.0
GSVIVG01023127001 Vitis vinifera HOM05D003302 ORTHO05D003785 7.5e-70 268.1 217 58.5
Actinidia03397 Actinidia chinensis HOM05D003302 ORTHO05D003785 9.8e-70 267.7 217 57.6
CAN.G572.44 Capsicum annuum HOM05D003302 ORTHO05D003785 9.8e-70 267.7 217 58.1
MELO3C003368.2 Cucumis melo HOM05D003302 ORTHO05D003785 9.8e-70 267.7 217 59.0
Rhsim04G0067200 Rhododendron simsii HOM05D003302 ORTHO05D003785 9.8e-70 267.7 208 59.1
Solyc08g077385.1 Solanum lycopersicum HOM05D003302 ORTHO05D003785 9.8e-70 267.7 217 58.1
Sopen08g025970 Solanum pennellii HOM05D003302 ORTHO05D003785 9.8e-70 267.7 217 58.1
vmacro00359 Vaccinium macrocarpon HOM05D003302 ORTHO05D003785 9.8e-70 267.7 208 59.1
Nitab4.5_0004832g0030 Nicotiana tabacum HOM05D003302 ORTHO05D003785 1.3e-69 267.3 217 58.1
Nitab4.5_0008694g0030 Nicotiana tabacum HOM05D003302 ORTHO05D003785 1.3e-69 267.3 217 58.1
TPR.G26325 Trifolium pratense HOM05D003302 ORTHO05D003785 1.3e-69 267.3 208 59.6
Duzib205G0194 Durio zibethinus HOM05D003302 ORTHO05D003785 1.7e-69 266.9 208 60.1
Psat1g168040 Pisum sativum HOM05D003302 ORTHO05D003785 1.7e-69 266.9 208 59.1
PGSC0003DMG400001864 Solanum tuberosum HOM05D003302 ORTHO05D003785 1.7e-69 266.9 217 58.1
Sabra03G0056500 Salix brachista HOM05D003302 ORTHO05D003785 2.2e-69 266.5 208 58.7
THA.LOC104798339 Tarenaya hassleriana HOM05D003302 ORTHO05D003785 2.2e-69 266.5 208 59.1
DCAR_005601 Daucus carota HOM05D003302 ORTHO05D003785 2.8e-69 266.2 208 58.7
Aa31LG9G6000 Aethionema arabicum HOM05D003302 ORTHO05D003785 3.7e-69 265.8 208 59.6
A06p45460 Brassica napus HOM05D003302 ORTHO05D003785 3.7e-69 265.8 208 60.1
C07p30510 Brassica napus HOM05D003302 ORTHO05D003785 3.7e-69 265.8 208 60.1
BolC7t43592H Brassica oleracea HOM05D003302 ORTHO05D003785 3.7e-69 265.8 208 60.1
BraA06t27414Z Brassica rapa HOM05D003302 ORTHO05D003785 3.7e-69 265.8 208 60.1
Dinv28907 Davidia involucrata HOM05D003302 ORTHO05D003785 4.9e-69 265.4 217 58.1
Sp2g11710 Schrenkiella parvula HOM05D003302 ORTHO05D003785 4.9e-69 265.4 208 60.1
Atru.chr6.1790 Acer truncatum HOM05D003302 ORTHO05D003785 6.3e-69 265.0 208 59.1
CAN.G289.41 Capsicum annuum HOM05D003302 ORTHO05D003785 6.3e-69 265.0 217 57.6
Sc25g0000590 Simmondsia chinensis HOM05D003302 ORTHO05D003785 8.3e-69 264.6 217 57.6
EL10Ac5g11380 Beta vulgaris HOM05D003302 ORTHO05D003785 1.4e-68 263.8 217 58.1
AUR62025829 Chenopodium quinoa HOM05D003302 ORTHO05D003785 1.4e-68 263.8 208 59.1
PSO063G6934 Papaver somniferum HOM05D003302 ORTHO05D003785 1.4e-68 263.8 208 59.1
PSO782G0278 Papaver somniferum HOM05D003302 ORTHO05D003785 1.8e-68 263.5 208 59.1
Cfa012369 Carpinus fangiana HOM05D003302 ORTHO05D003785 2.4e-68 263.1 208 58.2
Haze_08314 Corylus avellana HOM05D003302 ORTHO05D003785 2.4e-68 263.1 208 58.2
Haze_08315 Corylus avellana HOM05D003302 ORTHO05D003785 2.4e-68 263.1 208 58.2
Lsat_1_v5_gn_4_38500 Lactuca sativa HOM05D003302 ORTHO05D003785 2.4e-68 263.1 217 57.1
Potri.003G086801 Populus trichocarpa HOM05D003302 ORTHO05D003785 2.4e-68 263.1 208 57.7
AUR62029877 Chenopodium quinoa HOM05D003302 ORTHO05D003785 3.1e-68 262.7 208 58.7
HanXRQChr16g0522971 Helianthus annuus HOM05D003302 ORTHO05D003785 3.1e-68 262.7 217 57.1
ECA248G2391 Erigeron canadensis HOM05D003302 ORTHO05D003785 4.1e-68 262.3 217 57.6
SHI07509 Sapria himalayana HOM05D003302 ORTHO05D003785 5.4e-68 261.9 217 58.5
CiPaw.12G059400 Carya illinoinensis HOM05D003302 ORTHO05D003785 7.0e-68 261.5 208 57.7
AL8G11350 Arabidopsis lyrata HOM05D003302 ORTHO05D003785 9.2e-68 261.2 208 58.2
AT5G46920 Arabidopsis thaliana HOM05D003302 ORTHO05D003785 2.7e-67 259.6 208 57.7
MD10G1262500 Malus domestica HOM05D003302 ORTHO05D003785 2.7e-67 259.6 157 82.8
HanXRQChr07g0188531 Helianthus annuus HOM05D003302 ORTHO05D003785 1.3e-66 257.3 217 55.8
FAN04G1622 Fragaria x ananassa HOM05D003302 ORTHO05D003785 5.4e-60 235.3 183 59.6
CDE12G0679 Ceratophyllum demersum HOM05D003302 ORTHO05D003785 5.2e-55 218.8 217 53.5
CDE06G1020 Ceratophyllum demersum HOM05D003302 ORTHO05D003785 1.2e-54 217.6 217 53.0
Nn6g33801 Nelumbo nucifera HOM05D003302 ORTHO05D003785 2.0e-54 216.9 164 64.0
Glyma.13G218051 Glycine max HOM05D003302 ORTHO05D003785 2.2e-45 186.8 98 94.9
arahy.Tifrunner.gnm1.ann1.G4BUBZ Arachis hypogaea HOM05D003302 ORTHO05D003785 3.9e-42 176.0 120 72.5
Actinidia16714 Actinidia chinensis HOM05D003302 ORTHO05D003785 2.8e-40 169.9 172 57.0
unitig_65.g29877 Utricularia gibba HOM05D003302 ORTHO05D003785 6.9e-31 138.7 98 65.3
CAN.G572.50 Capsicum annuum HOM05D003302 ORTHO05D003785 1.4e-28 131.0 98 63.3
CAN.G15328.1 Capsicum annuum HOM05D003302 ORTHO05D003785 3.0e-26 123.2 122 52.5
CAN.G572.51 Capsicum annuum HOM05D003302 ORTHO05D003785 4.3e-25 119.4 92 56.5
Actinidia25937 Actinidia chinensis HOM05D003302 ORTHO05D003785 1.6e-16 90.9 155 30.3
MD06G1041700 Malus domestica HOM05D003302 ORTHO05D003785 1.1e-15 88.2 73 49.3
ATR0665G600 Amborella trichopoda HOM05D003302 ORTHO05D003785 3.5e-11 73.2 57 64.9
Pp3c26_11300 Physcomitrium patens HOM05D003302 ORTHO05D003785 3.0e-10 70.1 208 27.9
BcaC03g16904 Brassica carinata HOM05D003302 ORTHO05D003785 3.1e-07 60.1 51 54.9
AagrBONN_evm.TU.Sc2ySwM_344.5534 Anthoceros agrestis HOM05D003302 ORTHO05D003785 4.0e-07 59.7 87 33.3


User provided reference genes

Program Settings