Module
- Number
- 92
- Regulatory Genes
- 1
- Module Genes
- 15
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
Y17G7B.20 | Y17G7B.20 | WBGene00012471 | 758 | View |
CLR Predictions
6 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
acbp-1 | C44E4.6 | WBGene00016655 |
acbp-1 encodes an Acyl-CoA-binding protein; loss of acbp-1 activity via RNAi results in reduced fat content indicating that ACBP-1 plays a role in lipid metabolism.
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atp-4 | T05H4.12 | WBGene00020275 | View | |
cco-2 | Y37D8A.14 | WBGene00012553 | View | |
cts-1 | T20G5.2 | WBGene00000833 |
cts-1 encodes a citrate synthase, predicted to be mitochondrial, that is required for embryonic development.
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cyn-5 | F31C3.1 | WBGene00000881 |
cyn-5 encodes a cyclophilin that is functional in vitro and is predicted to be a secreted protein that is structurally most similar to human cyclophilin B; expressed in the intestine.
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F29B9.11 | F29B9.11 | WBGene00017925 | View | |
F29C4.2 | F29C4.2 | WBGene00017926 | View | |
F36A2.7 | F36A2.7 | WBGene00009454 | View | |
M28.5 | M28.5 | WBGene00010896 | View | |
pdi-1 | C14B1.1 | WBGene00003962 |
pdi-1 encodes a protein disulfide isomerase; loss of function mutations in pdi-1 result in no obvious abnormalities, but animals triply mutant for three C. elegans PDI's, encoded by pdi-1, pdi-2, and pdi-3, display embryonic lethality characterized by loss of vermiform morphology after elongation, suggesting that the pdi genes function redundantly in embryonic morphogenesis; PDI-1 exhibits protein disulfide isomerase activity and protein-glutamine gamma-glutamyltransferase activity in vitro; pdi-1::lacZ reporter fusions are expressed in the hypodermis.
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pdi-3 | H06O01.1 | WBGene00003964 |
pdi-3 encodes a protein disulfide isomerase (PDI) required for normal cuticle collagen deposition and, subliminally, for maintenance of normal body shape; PDI-3 has both PDI and calcium-dependent transglutaminase activity in vitro, crosslinking proteins through a gamma-glutamyl epsilon-lysine dual residue; PDI-3 is homologous to the human PDI ERp60, as well as a homolog in the dog heartworm Dirofilaria immitis that is required for larval molting; the joint PDI/transglutaminase activity of PDI-3 is biochemically conserved in nematodes and mammals; pdi-3 is constitutively and broadly expressed, particularly in gut and hypodermis.
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R04F11.2 | R04F11.2 | WBGene00011015 | View | |
R11A5.4 | R11A5.4 | WBGene00011232 | View | |
tba-2 | C47B2.3 | WBGene00006529 |
tba-2 encodes a tubulin with similarity to the murine alpha-2 chain; in small scale assays tba-1(RNAi) has no phenotype and was found to function redundantly with its isotype tba-1 to form spindle structures in embryos with the tbb-1 and tbb-2 beta-isotypes.
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W09C5.8 | W09C5.8 | WBGene00012354 | View |