Module
- Number
- 35
- Regulatory Genes
- 5
- Module Genes
- 38
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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ctbp-1 | F49E10.5 | WBGene00006424 | 552 |
tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
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T22E7.2 | T22E7.2 | WBGene00020694 | 546 | View | |
nhr-167 | C49F5.4 | WBGene00008208 | 322 | View | |
nhr-7 | F54D1.4 | WBGene00003606 | 202 | View | |
gpa-18 | W03F8.9 | WBGene00020997 | 187 |
gpa-18 encodes a divergent G protein alpha subunit, with roughly as much similarity to fungal as to metazoan homologs.
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CLR Predictions
11 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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acc-3 | F55D10.5 | WBGene00018880 | View | |
amt-3 | M195.3 | WBGene00000135 |
amt-3 encodes one of four C. elegans homologs of AMT1 (AT11_ARATH), a high-affinity ammonium transporter from Arabidopsis thaliana; AMT-3 is closely similar to its paralog AMT-2, with somewhat more distant paralogy to AMT-1 and AMT-4.
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C15B12.2 | C15B12.2 | WBGene00015784 | View | |
C30A5.6 | C30A5.6 | WBGene00016240 | View | |
C32C4.1 | C32C4.1 | WBGene00007862 | View | |
C37C3.11 | C37C3.11 | WBGene00016503 | View | |
C45G9.11 | C45G9.11 | WBGene00016682 | View | |
ceh-45 | ZK993.1 | WBGene00022837 |
ceh-45 encodes a homeodomain-containing protein; loss of ceh-45 activity via large-scale RNAi results in variable embryonic lethality.
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dsc-1 | C18B12.3 | WBGene00001096 | View | |
F23H12.7 | F23H12.7 | WBGene00009095 | View | |
F37A4.6 | F37A4.6 | WBGene00018136 | View | |
F38B6.2 | F38B6.2 | WBGene00018172 | View | |
F44A6.3 | F44A6.3 | WBGene00009675 | View | |
F44G4.7 | F44G4.7 | WBGene00009716 | View | |
F46C5.4 | F46C5.4 | WBGene00009780 | View | |
F57A8.4 | F57A8.4 | WBGene00010179 | View | |
H03E18.2 | H03E18.2 | WBGene00019149 | View | |
K12B6.4 | K12B6.4 | WBGene00019669 | View | |
mod-1 | K06C4.6 | WBGene00003386 |
mod-1 encodes a serotonin-gated chloride channel; MOD-1 activity is required for locomotory behavior, specifically for the experience-dependent behavior of an enhanced slowing response exhibited by food-deprived animals upon encountering a bacterial food source; when expressed in voltage-clamped Xenopus oocytes, MOD-1 is able to form a serotonin-gated ion channel, and when expressed in human tissue culture cells, MOD-1 exhibits behavior consistent with chloride selectivity; a rescuing MOD-1::GFP construct is expressed in the cell bodies and axons (the latter presumably due to overexpression) of neurons in the head, tail, and ventral nerve cord.
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mps-1 | C29F5.4 | WBGene00003403 |
mps-1 encodes single-pass transmembrane proteins that are related to the vertebrate KCNE proteins, also known as MinK-related peptides (MiRPs) that associate with, and regulate, pore-forming ion channels; mps-1 is required for the normal function of several neurons and thus for normal body touch sensation, chemotaxis to select molecules, osmotic avoidance, and nose-touch; when assayed in ASER neurons or in tissue culture cells coexpressing C. elegans KVS-1, MPS-1 is able to alter the activity of this potassium-selective channel, suggesting that MPS-1 functions in vivo to regulate KVS-1 activity in neurons in which the two proteins are coexpressed; mps-1 reporter fusions are expressed in the vulva and in several chemosensory and mechanosensory neurons, including the ADF neuron.
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ncx-10 | Y97E10B.7 | WBGene00003575 |
ncx-10 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-9; NCX-10 may function intracellularly; NCX-10 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-10 has no obvious function in mass RNAi assays.
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pde-5 | C32E12.2 | WBGene00016328 | View | |
R04F11.1 | R04F11.1 | WBGene00011014 |
R04F11.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; R04F11.1 is worm-specific, with obvious homologs only in C. elegans; R04F11.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
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R08A2.5 | R08A2.5 | WBGene00011136 | View | |
R12G8.1 | R12G8.1 | WBGene00011254 | View | |
sra-10 | F44F4.5 | WBGene00005036 | View | |
srab-14 | R10H1.2 | WBGene00019999 | View | |
srd-49 | R04B5.8 | WBGene00005127 | View | |
srd-51 | F15A2.3 | WBGene00005129 | View | |
sro-1 | D1022.6 | WBGene00005641 | View | |
sru-46 | C45H4.5 | WBGene00005709 | View | |
srx-2 | R03H4.2 | WBGene00005893 | View | |
T09B9.3 | T09B9.3 | WBGene00011644 | View | |
T19D12.7 | T19D12.7 | WBGene00020582 | View | |
tag-49 | AC7.1 | WBGene00006428 | View | |
W01B6.3 | W01B6.3 | WBGene00012170 | View | |
Y41D4B.1 | Y41D4B.1 | WBGene00021511 | View | |
ZK112.5 | ZK112.5 | WBGene00022661 | View |