Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name
R04F11.1  
Sequence Name
R04F11.1  
WB ID
WBGene00011014  
Description
R04F11.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; R04F11.1 is worm-specific, with obvious homologs only in C. elegans; R04F11.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.  


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