InterPro domain: IPR045053

This family includes mannan endo-1,4-beta-mannosidases from plants and fungi ( 3.2.1.78 ). They catalyse the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans and are crucial for depolymerization of seed galactomannans and wood galactoglucomannans [ 1 , 2 ]. The deconstruction of the plant cell wall has had increasing importance as a key biological process in the development of a sustainable biofuel industry [ 3 ]. In plants, they are related to the process of weakening the tissues surrounding the embryo during seed germination [ 3 ].

This entry also includes cellulase domain-containing proteins from bacteria.

1. An Aspergillus nidulans β-mannanase with high transglycosylation capacity revealed through comparative studies within glycosidase family 5. Appl Microbiol Biotechnol
2. Structural and biochemical analyses of glycoside hydrolase families 5 and 26 beta-(1,4)-mannanases from Podospora anserina reveal differences upon manno-oligosaccharides catalysis. J. Biol. Chem. 74, 767-80
3. Arabidopsis thaliana bZIP44: a transcription factor affecting seed germination and expression of the mannanase-encoding gene AtMAN7. Plant J 98, 10091-104