InterPro domain: IPR045034

This entry represents O-acyltransferases mainly from plants and bacteria, including WSD1 from Arabidopsis thaliana, a bifunctional wax ester synthase/diacylglycerol acyltransferase, which is involved in cuticular wax biosynthesis and is required to reduce leaf water loss, especially during drought [ 1 , 2 ]. This family also includes tgs1-4 from Mycobacterium tuberculosis, which function as triacylglycerol synthases with very weak or no wax synthase activity [ 3 ].

1. Identification of the wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase WSD1 required for stem wax ester biosynthesis in Arabidopsis. Plant Physiol. 148, 97-107
2. Surface wax esters contribute to drought tolerance in Arabidopsis. Plant J 98, 727-744
3. Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture. J Bacteriol 186, 5017-30