InterPro domain: IPR045003

This family represents Group A Fasciclin-like arabinogalactan proteins (FLAs) from plants, which includes FLAs 6, 7, 9,11,12 and 13 from Arabidopsis [ 1 ]. They are probably cell surface adhesion proteins.Fasciclin-like arabinogalactan proteins (FLAs) proteins from Arabidopsis, a subclass of arabinogalactan proteins (AGPs), can be classified in four groups (A-D) based on pair-wise sequence similarity, domain structure, and phylogenetic analysis [ 2 ]. Group A FLAs are characterised by a single fasciclin domain that is flanked by AGP regions and a C-terminal GPI-anchor signal; group B contain two fasciclin domains flanking an AGP region and lack a C-terminal GPI anchor signal sequence; group C have a variable domain structure with one or two fasciclin domains, one or two AGP regions, and a C-terminal GPI anchor signal; FLAs 4 and 19 to 21 formed group D as they have low similarity to each other or to any of the other FLAs [ 2 ].

1. The fasciclin-like arabinogalactan proteins of Arabidopsis. A multigene family of putative cell adhesion molecules. Plant Physiol. 133, 1911-25