InterPro domain: IPR044848

This entry includes protein PHOSPHATE STARVATION RESPONSE 1 (PHR1) and its homologues, including PHLs from Arabidopsis thaliana. They belong to a family of MYB-CC transcription factors and are regarded as the key components of the central regulatory system controlling plant transcriptional responses to phosphate (Pi) starvation [ 1 , 2 , 3 ]. PHR1 is a transcription factor and a master regulator of phosphate starvation responses (PSRs) [ 4 ]. PHL1 (PHR1-LIKE 1), PHL2, and perhaps also PHL3, act redundantly with PHR1 to regulate plant Pi starvation responses [ 5 ]. However, PHL4 has only a minor role in the regulation of plant responses to Pi starvation [ 5 ]. PHL10 (also known as MYR1) acts redundantly with PHL9 (also known as MYR2) as a repressor of flowering and organ elongation under decreased light intensity [ 5 ].

1. Arabidopsis PHL2 and PHR1 Act Redundantly as the Key Components of the Central Regulatory System Controlling Transcriptional Responses to Phosphate Starvation. Plant Physiol 170, 499-514
2. Functional Characterization of Arabidopsis PHL4 in Plant Response to Phosphate Starvation. Front Plant Sci 9, 1432
3. Integrative Comparison of the Role of the PHOSPHATE RESPONSE1 Subfamily in Phosphate Signaling and Homeostasis in Rice. Plant Physiol 168, 1762-76
4. SPX1 is a phosphate-dependent inhibitor of Phosphate Starvation Response 1 in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A. 111, 14947-52
5. Methionine-independence, tumorigenicity and oncogene expression of rat hepatocarcinoma cells. Biol Cell 69, 113-8