InterPro domain: IPR044835
General Information
- Identifier IPR044835
- Description Auxin response factor
- Number of genes 3031
- Gene duplication stats Loading...
- Associated GO terms GO:0003677 GO:0006355 GO:0009725
Abstract
The plant hormone auxin (indole-3-acetic acid) can regulate the gene expression of several families, including Aux/IAA, GH3 and SAUR families. Two related families of proteins, Aux/IAA proteins ( IPR003311 ) and the auxin response factors (ARF), are key regulators of auxin-modulated gene expression [ 1 ]. There are multiple ARF proteins, some of which activate, while others repress transcription. ARF proteins bind to auxin-responsive cis-acting promoter elements (AuxREs) using an N-terminal DNA-binding domain. It is thought that Aux/IAA proteins activate transcription by modifying ARF activity through the C-terminal protein-protein interaction domains found in both Aux/IAA and ARF proteins.
1. Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol. Biol. 49, 387-400