InterPro domain: IPR044800

This entry represents a group of plant B3 domain-containing transcription factors, including LEC2, NGA1/2/3/4, RAV1/2 and related proteins from Arabidopsis. LEC2 plays a central role in embryo development [ 1 ]. RAV1 binds specifically to bipartite recognition sequences composed of two unrelated motifs, 5'-CAACA-3' and 5'-CACCTG-3' [ 2 , 3 ]. RAV2 has been shown to affect FT expression [ 4 ]. NGA1/2/3/4 regulate lateral organ growth [ 5 ].

1. Genes directly regulated by LEAFY COTYLEDON2 provide insight into the control of embryo maturation and somatic embryogenesis. Proc Natl Acad Sci U S A 103, 3468-73
2. RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants. Nucleic Acids Res. 27, 470-8
3. Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development. Cell Res 14, 8-15
4. The balance between CONSTANS and TEMPRANILLO activities determines FT expression to trigger flowering. Curr Biol 18, 1338-43
5. Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species. Plant Cell 18, 1134-51