InterPro domain: IPR044684

This entry represents a group of rhodanese-like domain-containing proteins from bacteria, archaea and plants, including STR17/STR18/HARC1 from Arabidopsis. HARC1 is an arsenate reductase that reduces arsenate to arsenite in the root, facilitating efflux of arsenic back into the soil to limit both its accumulation in the root and transport to the shoot [ 1 ]. STR17/STR18 are sulfurtransferases [ 2 ]. STR18 catalyses the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds [ 3 ].

1. Genome-wide association mapping identifies a new arsenate reductase enzyme critical for limiting arsenic accumulation in plants. PLoS Biol 12, e1002009
2. Intracellular localization of Arabidopsis sulfurtransferases. Plant Physiol 135, 916-26
3. Identification and characterization of single-domain thiosulfate sulfurtransferases from Arabidopsis thaliana. FEBS Lett 532, 427-31