InterPro domain: IPR044675

This entry represents a group of RING-H2 finger proteins mostly from plants, including RING1 (also known as ATL55, At5g10380) and related proteins from Arabidopsis. RING1 is an E3 ubiquitin-protein ligase that may be involved in positive regulation of programmed cell death (PCD) by facilitating degradation of negative regulators of PCD [ 1 ].

1. RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis. Plant J 56, 550-61